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5 Cards in this Set

  • Front
  • Back
Penicillins
Mechanism:Bind PBPs; inhibit formation of bridges in peptidoglycan.
Antimicrobial Action: Bactericidal.
Spectrum: Gram positive.
Inhibition:Beta-lactamases;
Efflux of drug;
Porin size (Gm -).
Notes: PenG=IV, IM
PenV=PO
1st gen.;
effective vs. growing bacteria.
Methicillin
Mechanism: Bind PBP's, Antimicrobial Action: Bacteriocidal
Inhibition: Same as Penicillin.Spectrum:Gram Positive
Notes: Beta Lactamases, Resistant to inactivation by penicillinase of CA-MRSA.
Ampicillin
Amoxicillin
Mechanism: Bind PBP's, Microbial Action: Bacteriocidal
Spectrum: Gm+; growing E. coli, Proteus.
Inhibition: Same as Penicillin.Notes: PO 2nd Generation.
Carbenicillin
Ticarcillin
Mechanism: Bind PBP's, Microbial Action: Bacteriocidal
Spectrum: Gm+ &
Gm-, incl. Pseudomonas.
Inhibition: Resistant to B-lactamases.
Notes:Narrow spectrum
given to those allergic to penicillin.
Monobactams
(Aztreonam)
Microbial Action: Bacteriocidal
Spectrum: Aerobic Gm-;
Enterobac-teriaceae.
Inhibition: Same as Penicillin.
Notes: PO 3rd Generation.