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7 Cards in this Set

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GENERAL CONCEPTS
A. Definition of "Anaerobe" Bacteria
require a reduced oxygen tension for growth and fail to grow on the surface of solid media in 10% C02 in air
MAJOR ANAEROBIC INFECTION SYNDROMES
A. Head and Neck Chronic sinusitis, chronic otitis, space infections, Ludwig's angina, periodontal abscess, brain abscess, subdural empyema

B. Pulmonary Aspiration pneumonia, necrotizing pneumonia, lung abscess, empyema

C. Intraabdominal Peritonitis and abscesses, liver abscess

D. OB-Gyn Salpingitis, tub ovarian abscess, vulvovaginal abscess, septic abortion, and endometritis

E. Skin and soft tissue
Cellulitis, necrotizing fasciitis, myonecrosis, decubitis ulcers, diabetic foot ulcers, vascular insufficiency ulcers, bite wounds
II. GENERAL CLINICAL CLUES TO ANAEROBIC INFECTION
A. Infections contiguous to mucosal surfaces

B. Foul smell (only 50%)

C. Severe tissue necrosis with fasciitis, abscesses, and gangrene

D. Gas in tissue

E. Gram-stain appearance of multiple forms, or unique anaerobic forms

F. Failure to grow organisms by aerobic techniques

G. Lack of response to antibiotics ineffective against anaerobes
SPECIFIC ORGANISMS
Bacteroides

Fusobacterium species
-2. Common infections occur primarily in the head and neck: chronic sinusitis, otitis
Anaerobic cocci
common infections
Peptococcus / Peptostreptococcus.

Common infections include postoperative wounds, orofacial, skin, pleuropulmonary, intraabdominal, and pelvic infections, brain abscess, and diabetic foot ulcers.
LABORATORY METHODS FOR ANAEROBES
Acceptable methods of collection
(a) Needle and syringe aspirate of abscesses and normally sterile body fluids
(b) Transtracheal aspirate or direct lung aspirate of pulmonary sources
(c) Culdocentesis and possibly double-lumen-protected swabs of endometrial contents.
(d) Suprapubic aspiration of urine
(e) Biopsies of normally sterile tissue
Specimens that are unacceptable
(a) Pus from superficial or open wounds (includes decubiti, other ulcers)
(b) Lower genital tract in women and urethra in both sexes
(c) Pharyngeal, oral, nasal, dental, eye, ear, sputum, nasotracheal aspiration cultures
(d) Stool, gastric contents
(e) Clean catch and catheter obtained urines
(f) Specimens taking longer than 2-3 hours to reach laboratory