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36 Cards in this Set
- Front
- Back
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What is the most pathogenic strain on Influenza? |
Influenza A (undergoes antigenic drift --> shift) |
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What is unique to Influenza? |
Replicates in the Nucleus
ssRNA Can cause secondary pneumonia |
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What is unique to influenza A? |
most pathogenic strain strain based on surface proteins (hemaglutinin (H 1-7) and Neuraminidase (N 1 -9) Hemaglutinin Binds Sialic Neuraminidase Cleaves Sialic |
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What is unique about Paramyoxyviruses? |
Non- segemented Group V - ssRNA (RSV, Measles, Mumps, Hpiv) |
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Unique to RSV (respiratory syncitail virus) |
- most children under 3 will get RSV (in adults - common cold) - Have F protiens on surface that make F proteins on the membrane of other cells to merge and form Syncitail. - Major cause of LOWER RESP. Infection. |
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What is unique to Hpiv? (human parainfluenza virus) |
NOT INFLUENZA - 2nd most common (1st cause is RSV) cause of hospitalization in kids (upper and lower in kids) - upper resp. (in adults) - have F proteins too - Causes Croup (larynx, trachea, bronchi) - barking cough |
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What is unique to Measles? |
Also called Rubeola highly contagoues >104F fever, rhinorritis, pink eye 30% result in complications (in adults more) diarrhea, encephalitis, blindess. Get Kopliks spots (white on tongue) |
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What is unique to Mumps? |
Highly contageous swelling of PAROTID gland Can lead to deafness, inflammation of testicles/ infertility and meningitis, encephalitis NO TREATMENT. |
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What is unique about Rubella? |
Group IV + ssRNA Can cross the placenta (give baby congenital rubella syndrome CRS) pink rash on SIDE of face, then spread. TRIAD: Deafness, Eye abnormalities, Congenital health problems |
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What is unique to Adenovirus? |
LARGEST non-enveloped virus Group 1 dsDNA Many strains(ppl can get more than 1 strain) common cold, rhinitis, pink eye, gastroenteritis. Spread via respiratory but also oral - fecal. Early genes - needed to produce resy Late genes - structural |
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What is unique about Rhinoviruses? (Picornoviridae) |
Group IV ssRNA Common cold proliferates in 91-95 degrees F (nose temperature) |
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Which viruses replicate in the nucleus? |
Influenza Herpes |
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What is unique about Herpes I and II |
Group I, dsDNA, forms Episomes, replicates in the NUCLEUS. I - cold sore (trigeminal ganglia) II - genital (sacral ganglia) |
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What is unique about EBV (Epstein barr virus)? |
latency occurs in B cell 90% cause of Mono in adults who dont aquire it when theyre young. Can cause B cell cancers (Berkitts lymphoma) |
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What is unqiue about CMV (Cytomegalovirus)? |
Latency in T cells and monocytes. It is congenital, passed on during pregnancy. Canhave many complications |
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What is Roseola? |
6th disease rash on babies but can occur in adults fever first then rashs on legs, back and trunk. |
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What is unique about Kaposis sarcoma associated herpes virus? (KSAH) |
It can be in ppl but healthy ppl wont even show symptoms and will fight it unknowingly. Kaposi's sarcoma = soft tissue cancer AID defying illness. It kills ppl with AIDS because it causes cancer and they are immunocompromised. |
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What is significant about Poxviridae? |
LARGE virus (can't fit in the nucleus) occurs in CYTOPLASM Group 1, dsDNA Has its own DNA dependant RNA poly. Brick shaped or oval. |
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What is unqiue about Variola Virus (Poxviridae)? |
SMALL POX (in mouth, and turns into blisters) Variola major - severe, high martality rate Variola minor - less sever, low mortality rate. Has a live vaccine (dangerous) causes flue like symptoms. 1st eradicated virus |
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what is unique to HPV? |
In Nucleus group 1, dsDNA Genital warts, cancer, tree man affects non-differentiated basal cells and keratinocytes. |
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What is the subtype for genital warts? |
HPV 6, HPV 11 |
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What is the subtype for HPV cancer? |
HPV 16, HPV 18 |
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What is the baltimore system for hepatits? |
Hep A, C, D, E: ssRNA Hep B: dsDNA -RT |
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What is unique about Hepatitis A? |
Picorniviridae Group IV ssRNA IN cYTOPLASM food and water LINEAR NON ENVELOPED (B and C are enveloped) |
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What is unqiue about Hepatitis B? |
Group VII, ssDNA - RT In nucleus from blood/ bodily fluids. Circular MOST COMMON HEPATITIS WORLDWIDE. |
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What is unique about hepatitis C? |
Group IV (like A), ssRNA Flavirius gorup JAUNDICE is rarely seen 80% will develop chronic. Extrahepatic issues can develop. |
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What is significant about hep D? |
Deltavirus family Group V is a Satellite virus = needs hep B to replicate only infects cells infected with hep B |
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What is unique about hepatitis E? |
Hepevirus family group IV, non enveloped ss rna Isocohedral structure (like hep A) water/ meat pregnant women and immunocompromised ppl can die and get sick from hep E |
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whch hepatitis groups are non enveloped? |
Hep A Hep E |
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Which hepatitis are group IV? |
Hep A Hep C Hep E |
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Which hep viruses have an isochodral shape?
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hep A and hep E |
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What is unique about parvovirus B19 virus? |
5th disease in children (rash on cheeks then spread to extremities) flu in adults group II |
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Rotavirus |
Enteric virus non enveloped group III isocahedral shape most common cause of diarrhea in children |
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Norovirus |
Stomach flu (viral gastroenteritis) group IV |
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What are the diff polio viruses in order from least occuring to most occuring? |
non paralytic paralytic bulbo bulbo spinal spinal |
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eNTEROVIRUSES ARE A GENUS OF WHAT? |
Picornoviridae. (polio, coxsackiveridae, entervirus D68) |
