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20 Cards in this Set
- Front
- Back
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Staphylococcus aureus characteristics
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-GPC tetrads, clusters
-circular, opaque, smooth, butyrous -white to yellow or golden -often hemolytic -catalase (H2O2) + -coagulase + |
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Coagulase - Negative Staphylococci
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-GPC
Staphylococcus epidermidis -white non hemolytic -catalase (H2O2) + -coagulase = Staphylococcus saprophyticus -same -sticky -novobiocin resistance test -UTI in young females |
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Staphylococcus aureus virulence
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-Enterotoxins
A&D Food Poisoning TSST-1 (toxic shock syndrom toxin) -Exfoliative toxin -Cytolytic toxins Hemolysins P-V leukocidin -Enzymes Coagulase Hyaluronidase Lipase Staphylokinase (Fibrinolysin) -Protein A (Allows Ig binding in the reverse direction) |
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Staphylococcus aureus infections
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Skin -Boils (Furnucle) Carbuncles Impetigo Wound
Respiratory -Pneumonia Urinary -Pyelonephritis Gastrointestinal -Food Poisoning -Protein Foods & salty Enterocolitis Osteomyelitis Systemic -Bacteremia Endocarditis Others -Scalded skin syndrome Toxic Shock Syndrome Nosocomial (Hospital acqired) |
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MRSA
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Methicillin-Resistant Staphylococcus aureus
Resistance via altered Penicillin Binding protein (PBP2a) PBP2a production encoded by mecA gene |
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Infections with coag negative Staphylococci
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Indwelling Foreign devices
tubes-catheters artificial implants (knees, hips, heart valves) |
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Micrococcus
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-GPC
Ubiquitous organisms Not associated w/ human infection GPC in clusters Resembles Staphylococcus, slow growing often pigmented -Catalase + -Coagulase = -Oxidative Glucose Utilization -Modified Oxidase + -Bacitracin Sensitive -Furazolidone Resistant |
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Stomatococcus
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-GPC
Found in Upper Respiratory Tract Resembles Staphylococcus on GS -Catalase = or weak + Rare infections of compromised hosts ie. endocarditis in IV drug users. |
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Staphylococcus Gram Stain
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GPC in pairs clusters and tetrads
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Streptococcus Gram Stain
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GPC in pairs and chains
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Streptococcus pyogens
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Group A Beta Strep
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M protein
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Major virulence factor of Group A Strep
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Streptolysin O
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Oxigen Labile
Lysis of RBCs Antigenic |
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Streptolysin S
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Oxigen Stabile
Lysis of RBCs Non Antigenic |
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Streptokinase
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Fibrinolysin of Streptococcus
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Erythrogenic toxin
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Exotoxin-Scarlet fever of Streptococcus
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Group A Strep characteristics
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-GPC in chains
-small, transparent, smooth -well defined area of beta hemolysis -some strains are mucoid |
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Group A Strep identification
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-catalase =
-Bacitracin (0.04U) susceptible -PYR + -Antigen typing |
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Group A Strep infections
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Strep throat
Scarlet Fever Impetigo Erysipelas Cellulitis Puerperal Fever Strep TSS (necrotizing fasciitis) |
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Group A Strep Sequelae
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Rheumatic Fever
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