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11 Cards in this Set
- Front
- Back
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What are some ways needed to propagate viruses
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They need viable cells for viral replication
So 1. Live animals 2. Embryonated eggs 3. Tissue/Cell culture |
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Plaques
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Used for enumeration of viruses in initial suspension
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Generalized effect on host
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Virus does not have predilection for just one cell type and can find receptors to bind to on many cells in different organs
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Specific effect on host
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They have tropism for specific system or organs
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Tropism
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Affinity of the virus to infect specific systems or organs
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What properties are common to viruses
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Genome
Protein Capsid Multiply only in living celsl After entering host cells, the initial step of viruses is to separate genome from capsid |
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Uncoating
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Separating genome from capsid
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Virion
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Infectious virus
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What are some features to distinguish viruses from bacteria
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Viruses cannot grow on artificial media
They don't divide by binary fission They don't contain both RNA and DNA They don't have a cell wall but a capsid instead |
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How can you classify viruses
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Type of nucleic acid in capsid
Double or single stranded Molecular weight Linear or circular (All DNA viruses are linear) Continuous or segmented Polarity of single stranded genome - positive or negative |
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Polio virus is a positive stranded RNA. What does that mean?
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It means that when they inject their genome into the cell it is recognize as mRNA and goes right to the ribosomes of the host cell to direct protein synthesis
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