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10 Cards in this Set
- Front
- Back
Neisseriae gonococcus attach via
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pili to mucosal epithelia of male urethra or female cervix; also surface proteins, and lipooligosaccharide
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disseminated gonococcal infection (DGI)
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localized gonococcal invades bloodstream and can cause acute dermatitis, arthritis, tenosynovitis
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what immune mechanism is effective against gonococcal infection
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late complement components via MAC
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what causes systemic signs of meningococcemia, DIC, and shock
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endotoxin released in blebs from organisms aka lipooligosaccharide (POS); induces release of TNF-a
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Neisseria specs
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gram-neg cocci; capsule (only N. meningitis); aerobes, but can grow anaerobically; cell envelopes; grow best with increased CO2; obligate human pathogens; twitching motility
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common microorganisms that use antigenic variation
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African trypanosomes, Borrelia species (relapsing fever), and N gonorrhoeae
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examples of on-off expression in microbes
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flagellar types in salmonella, pilus expression in gram-neg, E coli type I fimbriae expression
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Gonococcal copacity-associated proteins (Opa) are associated with
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PID, DGI, and arthritis; not engulfed by neutrophils
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agar used to grow gonococci
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chocolate agar (Thayer-Martin medium and Martin-Lewis medium=contain antibiotics to prevent growth of other bacteria)
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oxidative positive organisms
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member of Neisseria or close relative
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