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42 Cards in this Set
- Front
- Back
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The pathogens most responsible for secondary bacterial infections prior to flu are?
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Strep Pneu, Staoh A. and Pseudo
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The env gene is glycosylated to gp160 and
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Cleaved within the ER and Golgi to form gp120 and Gp41
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Formed from gp 160 from env what do gp120 and gp41 do?
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Gp120 mediates viral adsorption by binding to the cd4 receptor while transmembrane gp41 and chors 120 thorugh noncovalent interactions mediating FUSION
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Pulmonary blasto is characterized by a …
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Granulomatous infection
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Sputum stain with KOH is diagnostic for what.?
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….Broad baste Blastomycosis
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fungal hyphae branching in a V-shped pattern?
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…aspergillosis
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nonseptate hyphae branching at right angles?
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….mucormycosis…
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India ink stain of the CSF reveals a wide clear zone around the nucleus?
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….Cryptococcus neoformans…
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noninfective glycoprotein that forms spheres and tubules,infected hepatocytes may secrete enormous quantities of this glycoprotein?
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….HBsAg…
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nocleocapsid core protein of HBV that assembles virions ?
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…HBcAg
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precore protein that is a marker for high infectivity in hep B?
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…HBeAg
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the measles/rubeola virus is?
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…enveloped nonsegmented negative sense RNA virus…
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In typical measle/rubeola the cough coryza and koplik spots herald the development of a ?
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…cutaneous maculopapular rash…
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what precedes the rash in measles/rubeola?
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…koplic spots in the mouth…
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The Thayer martin VCN medium is?
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…a selective medium that kills Gram positives with vanc, other gram negs with colistin and fungi with nystatin to allow gonorrhea to grow…
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The Thayer martin VCN medium is?
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a selective medium that kills Gram positives with vanc, other gram negs with colistin and fungi with nystatin to allow gonorrhea to grow…
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Organisms that ferment lactose will appear purple on the mackokey agar and what on EMB?
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…black…
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In hepatitis B this antigen first appears before the onset of symptoms, peaks when the patients is most ill and then becomes undetectable at 3-6 months
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…HBsAg…
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Shortly after HbSAg appears?…
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HBeAg and HBV DNA can be detected in the serum and are markers of active replication….
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Appears shortly after HBeAg vanishes and suggests subsiding viral activity?
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…Anti-HBeAg…
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what suggests an acute Hep B that has pregressed to a highly infectious chronic hep B?
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…the persistence of HBeAg despite the coexistance of anti HBeAg
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persistent low levels of HbEAg?
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…chronic low infectivity HBV
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PArvo viruses are what?
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…nonenveloped single stranded DNA viruses
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Hep C is a single stranded?
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….positive sense RNA virus just like the HIV…
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important negative sense enveloped RNA viruses include?
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the flu (orthomyxo), measles mumps (paramyxo) and rabies…
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what other virus besides mycoplasma is associated with cold agglutinins?
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EBV…
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The BK virus is a DNA virus that causes one of two diseases?
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posttransplant nephropathy and a hemorrhagic cystitis
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what type of exonuclease activity is important in allowing enzymes such as DNA polymerase I to replace nucleotides in the repair of a growing strand of DNA?
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…5-3… for the Poly I…
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what type of exonuclease is proofreading?
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3-5…(p in proofreading comes before R in the alphabet so 3-5)…
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Is important in base-excision repair as it removes the nitrogenous base from the sugar-phosphate backbone?
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…DNA glycosylase…
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also given as a part of tetanus boosters in adults?
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diptheria toxoid…
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the conjugated Strep pneumo vaccine contains polysacharride antigens that are coupled with protein in order to ?
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stimulate a T-cell independent response…
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Hep B vaccine is what type?
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…recombinant surface protein vax
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Live attenuated bacterial vax?
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BCG and typhoid vax (salmonella)
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Live attenuated viral vaccines?
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Measles mumps rotavirus, Varicella as well as the sabin polio vax…
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inactivated toxoid vaccines include?
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Diptheria and tetanus
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Strep pneu cannot grow in the prescence of?
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…optochin or bile…
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etiologic agent of Q fever a mild pneumonia-like illness resulting from the inhalation of spores that commonly contaminate animal hides?
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C burnetti (a rickettsiae)….
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Hepatitis D virus is a what?
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…replicative defective RNA virus that is only capable of causinginfection with encapsulated HBsAg
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membranous glomerulopathy and cryoglobulinemia are two examples of?
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HCV
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When HAV contamination is a concern the virus can be inactivated via
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water chlorination, 1:1000 bleach, formalin, UV, or boiling to 85 celsius for a munute…
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what is the most important bacterial factor in the development of this infection (E. Coli meningitis)?
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…capsule so the K antigen…
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