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10 Cards in this Set

  • Front
  • Back
Each year infectious diseases account for what proportion of deaths worldwide?
1/3
Explain the difference between Developing country diseases and U.S. health diseases
The most frequently encountered serious infectious diseases in developing countries are not common health problems in the U.S.
How many colds do children normally contract each year?
5-6
What factors increase the frequency of common colds?
Day care center exposure
family members who smoke
Allergies and Asthma
Cystic Fibrosis
Congenital Immune Defects
Ciliary Dyskinesia
Name 4 viruses that can cause the Common Cold
Rhinoviruses
Influenza
Adenovirus
RSV
What does protective immunity to Influenza A virus depend on?
Neutralizing antibodies to HA and NA
What gives rise to Antigenic Drift?
gradual changes in the N and H serotypes by mutation
What gives rise to Antigenic Shift?
Reassortment of genomes between different strains
List the 6 Category A bioterrorism infectious agent threats
1. Bacillus anthracis
2. Clostridium botulinum toxin
3. Yersinia pestis
4. Variola major (smallpox)
5. Francisella tularensis
6. Viral hemorrhagic fever agents (i.e. Ebola virus)
Vaccines that can theoretically induce T-cell mediated immunity
DNA vaccines -> direct microbial protein synthesis in the host cell cytoplasm