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22 Cards in this Set

  • Front
  • Back
What are the gross changes seen 0-6 hrs after an MI?
None
What are the gross changes seen 12 hrs after an MI?
None
What are the gross changes seen 12-24 hrs after an MI?
Swelling and color change
What are the gross changes seen 24 hrs after MI?
Tan or red-brown infarct surrounding hyperemia
What are the gross changes seen 3 days after MI?
Increasingly yellow color of infarct
What are the gross changes seen 7 dyas after MI?
Yellow infarcted area surrounded by congested red border
What are the gross changes seen 10 days after MI?
Red. mewly formed vascular CT that encircles and gradually replaces yellow necrotic tissue
What are the gross changes seen 5 weeks after MI?
Increasing pallor of infarct b/c of progressive fibrosis
What are the gross changes seen 3-6 months after MI?
Well developed gray-white scar
What microscopic changes are seen 0-6 hrs after MI?
Slight swelling and cellular congestion
Vascular congestion surrounding lesion
What microscopic changes are seen 12 hrs after MI?
Neutrophils first appear in viable tissue adjacent to lesion
What microscopic changes are seen 12-24 after MI?
Cytoplasm becomes more acidophilic
Striations are lost
Nuclei disappear
Neutrophils infiltrate the lesion
What microscopic changes are seen 24 hrs after MI?
Well developed changes of coagulative necrosis
Progressive infiltration of neutrophils
What microscopic changes are seen 3 days after MI?
Neutrophils are replaced by macrophages
Phagocytosis of debris begins
What microscopic changes are seen 7 days after MI?
Beginning of growth of young fibroblasts and newly formed vessels into the lesion
REplacement of neutrophils by macrophages and phagocytosis continues
What microscopic changes are seen 10 days after MI?
Fibrovascular tissue growth continues
Almost complete replacement of neutrophils by macrophages
Phagocytosis almost complete
What microscopic changes are seen 2-4 weeks after MI?
Progressive synthesis of collagen and other intracellular matrix proteins
What microscopic changes are seen 5 weeks after MI?
Progressive fibrosis
What microscopic changes are seen 3-6 months after MI?
Mature fibrous tissue replaces area of infarction
When is arrhythmia most likely to occur following MI?
0-6 hrs (most common cause of death in early hours following MI)
What is the clinical risk during 4-7 days after MI?
Myocardial rupture --> cardiac tamponade
What is the clinical risk 3-6 months after MI?
Ventricular aneurysm can occur in scarred area