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3 Cards in this Set
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- Back
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Process of mac recognition to activation
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1) mac eats a pathogen, knows its bad, becomes activated
2) Activation = more costimulators (ex.CD40) 3) In addition to TCR-MHC, CD40-CD40 ligand on CD4 cell. 4) CD4 > activated > INF-gama 5) mac binds INF gama and becomes better killer. |
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Delayed type hypersensitivity (DTH)
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24-48 hours after injection of a previously exposed antigen into the skin, memory t cells home to site, causing inflammation and ect. Is basis of the TB test.
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What do NK inhibatory receptors bind?
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MHC 1 (so it dosent kill self)
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