Mfii Pharmacology Drugs

Front 1

atropine

Back 1

antagonist muscarinic receptors affecting the parasympathetic nervous system

Hint 1

useful for dangerously low heart rate

Front 2

metoprolol

Back 2

beta-1 adrenergic receptor antagonist affecting the sympathetic nervous system

Hint 2

useful for blood pressure, protective effect after heart attacks

Front 3

succinylcholine

Back 3

depolarizes NMJ, causing spastic paralysis - Tx prior to surgery

Hint 3

Cholinomimetic
Mimics Ach in the motor system - binds N1

Front 4

bethanechol

Back 4

to treat 'lazy gut'; causes GI and bladder contraction

Hint 4

Cholinomimetic
Mimics Ach in the parasympathetic system, specifically gut

Front 5

Physostigmine

Back 5

Acetycholine esterase inhibitor

Hint 5

Crosses blood brain barrier
Used to treat atropine OD

Front 6

Organophosphates (ex Parathion)

Back 6

Irreversible acetylcholine esterase inhibitor

Hint 6

Nerve gas
Rodent poison
TREAT with atropine and Pralidoxine

Front 7

Pralidoxine

Back 7

treat organophosphate poisoning

Front 8

Carbidopa

Back 8

Blocks decarboxylation of dopa to dopamine

Hint 8

Cannot cross blood brain barrier to prevents overproduction of dopamine, epi, and NE in rest of body when delivering L-dopa to parkinson's patients

Front 9

Tricyclics

Back 9

block reuptake of NE, serotonin

Hint 9

anti-depressant

Front 10

SSRIs

Back 10

block reuptake of serotonin

Hint 10

anti-depressant

Front 11

amphetamine

Back 11

blocks reuptake of NE/E

Hint 11

Catecholaminomimetics (sympathomimetic)

Front 12

cocaine

Back 12

blocks reuptake of NE/E

Hint 12

Catecholaminomimetics (sympathomimetic)

Front 13

ephedrine

Back 13

Blocks reuptake of NE/E/Ser
Works similarly to tri-cyclic antidepressants

Hint 13

Catecholaminomimetics

Front 14

MAOi

Back 14

Catecholaminomimetics - blocks the breakdown of NE in the cytoplasm after reuptake, increasing its concentration

Hint 14

Do not give with false transmitter. leads to excess NE in cleft and hypertensive crisis

Front 15

Clonidine

Back 15

alpha-2-receptor agonist

Hint 15

reduce hypertension by preventing release of NE/E
But reduction of release of NE/E in brain will make depression worse in depressed patients, contraindication
Sympatholytic

Front 16

Sympathomimetic

Back 16

stimultes post-synaptic excitatory alpha receptors only, will not bind pre-synaptic inhibitory alpha receptors

Front 17

Albuterol

Back 17

beta-2 agonist

Hint 17

bronchodilator in asthma

Front 18

Dopamine

Back 18

D1=D2>Beta-2>Beta1>alpha agonist

Hint 18

congestive heart failure - beta-1 agonist to force the heart to keep moving the blooding

Front 19

Dobutamine

Back 19

Beta-1>Beta-2 agonist

Hint 19

congestive heart failure- beta-1 agonist to force the heart to keep moving the blooding

Front 20

Atenolol

Back 20

beta-1 antagonist

Hint 20

post-MI protection to reduce stress on heart

Front 21

Lobetalol

Back 21

alpha-1>beta-1 antagonist

Hint 21

control hypertension

Front 22

Propranolol

Back 22

beta-1=beta-2 antagonist

Hint 22

control hypertension, but cannot use in an asthmatic patient

Front 23

Ergot alkaloids

Back 23

serotonin mimickers
Peripheral vasoconstrictors
CNS stimulators ("convulsive ergotism")

Hint 23

Like being treated with LSD

Front 24

Bromocriptine maleate

Back 24

serotonin agonist
parkinsonism
gynecomastia

Front 25

Melatonin

Back 25

serotonin agonist
resets biological sleep clock

Front 26

Ergonovine maleate

Back 26

serotonin agonist
stop postpartum bleeding by inducing oxytoxic effects