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3 Cards in this Set
- Front
- Back
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Local Therapy of Metastatic Breast Cancer |
Role of surgery or radiation (often stereotactic) • Chest wall lesion • Isolated pulmonary nodule • Hepatic metastases, but unlike GI cancer, role is far more questionable Brain metastases • Survival advantage associated with local therapy • Surgery • Radiosurgery • Coordinated multidisciplinary management is key Treatment of oligometastatic disease (? |
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When Else to Consider Local Therapy |
Disease is truly localized, Local symptoms are present and low chance of palliation with systemic rx, Impending localized complication (spinal cord compression, fracture), |
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Breast Surgery in Metastatic Disease |
Multiple retrospective, a few prospective studies –remains controversial
Patients who undergo breast surgery typically live longer than those who do not –but many uncontrolled variables
Underlying hypothesis is the breast serves as a site of ongoing tumor cell dissemination
Recently completed randomized trial in U.S.
RECOMMENDATION: option but not standard. Consider if local complications exist or oligometastatic. |
