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17 Cards in this Set
- Front
- Back
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Glargine |
Long-lasting insulin(2 Arginines to B chain carboxyl terminal) |
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determir |
Long-lasting insulin(Myristic acid + lysine amino acid at position B29) |
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Ultralente |
Long-lasting insulin( entirely crystalline Zinc) |
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Lente |
intermediate insulin ( 30% semilente + 70% ultralente insulin) |
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NPH |
intermediate insulin( insulin + protamine) |
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Human regular insulin |
Short acting ( Hexameter ard Zinc ion) |
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Lispo |
ultra-short insulin (Proline28,lysine 29) |
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Aspart |
ultra-short insulin( aspartic acid B28) |
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Adverse effect |
Hypoglycema,lipodystrophy at injection site |
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Orlistat |
Inhibit gastric and pancreatic lipases |
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Sulfonylureas(secretagogues) |
Pancreatic ß cells (stimulate insulin secretion)肥 |
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Meglitinide analogs(secretagogues) |
Pancreatic ß cells (stimulate insulin secretion)肥,less %hypoglycemia |
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Biguanides |
Liver(insulin sensitizer)inhibit glucose production X B12,lactic acidosis,肥 |
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Thiazolidinediones TZD |
Adipose tissue,muscle liver(bind PPAR increae sensitivity) |
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a-glucosidase inhibitors |
Gut,decrese glucose absortion (abdominal cramping) |
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GLP agonist |
Pancreatic a ß cells(increase insulin production but block glucagon secretion)GI |
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DPP-4 inhibitors |
Gut(increase GLP-1 levels by inhibiting DPP-4 -mediated degradation(infection) |
