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13 Cards in this Set
- Front
- Back
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Glycolysis regulation: major enzyme
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PFK-1
+AMP +F2,6BP -ATP, citrate Liver: ^ cAMP, v F2,6BP Muscle: ^ CAMP, ^ F2,6BP |
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Glycolysis reg: minor enzymes
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Pyruvate kinase, Pyruvate dehydrogenase, hexokinase, glucokinase (liver only)
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Pyr. kinase reg of g-colysis
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Liver: -cAMP dep de(P)
All: +F1,6BP -ATP |
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Pyr DH reg of g-colysis
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+CoA, NAD+
-acetyl CoA, NADH -non cAMP dep (P) |
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Gneogen.: where and major control
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-liver, kidney: mito and cytosol
-Major: F1,6B(P)tase -AMP -F2,6BP +ATP, citrate |
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Gneo: minor controls
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pyr carboxylase + acetyl CoA
ask |
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glycogen: important enzymes
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glyc phosphorylase and synthase
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glycogen phosphorylase
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-active with cAMP dependent phosphorylation via (P)ase kinase
^ Ca2+ activates kinase |
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glycogen synthase
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-inactive with cAMP dependent (P)ation
^Ca2+ increases (P)ation |
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Fatty acid degradation: location and important steps
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-mito
-Malonyl CoA inhibits carnitine acyl xferase I -hormone sensitive TG lipase in adipose + cAMP dep (P)ation |
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FA synthesis: location and major parts
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-cytosol
-acetyl CoA carboxylase +citrate -palmitoyl CoA -cAMP dep (P)ation |
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FA: cholesterol: location and enzyme
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cytoplasm
HMG-CoA reductase -cholesterol -cAMP dep (P)ation |
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FA: Ketogenesis: location and enzyme
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liver, mito
HMG-CoA synthase |
