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26 Cards in this Set

  • Front
  • Back
Anabolism or catabolism?
Anabolism or catabolism?
Catabolism
Does oxidation of carbon compounds release or require energy?
Release
Oxidation is loss of an electron or a...
hydrogen atom
Oxidation or reduction?
Oxidation or reduction?
Reduction
Give examples of 3 redox coenzymes
NAD, FAD, NADP
What is the ultimate electron acceptor?
Molecular oxygen
(hence why we need oxygen, ultimate stage of reactions)
What is a redox pair?
While one thing is oxidised, another is reduced
In what way are coenzymes electron carriers?
They are reduced
What does glycolysis break glucose down into?
Pyruvate (3C)
How many molecules of ATP are formed from glycolysis?
2 ATP
How many NAD molecules are used in glycolysis?
2
In the aerobic and anaerobic parts of respiration what happens to NAD?
Regenerated in mitochondria or in anaerobic, regenerated by formation of lactate
How much ATP does anaerobic glycolysis produce?
2 ATP
What is the energy production like in anaerobic respiration?
Faster energy production
Short duration of energy
e.g. white muscle fibres
Which organ converts lactate back to pyruvate?
Liver
Where does the citric acid cycle occur?
Inner matrix of mitochondria
What is the carbon input to the citric acid cycle?
Acetic acid bound to coenzyme A = acetyl coA
What other inputs apart from pyruvate may be used for acetyl coA?
Acetate, butyrate - ruminants and hindgut fermenters
Acetoacetate - (ketones in starvation)
Amino acids - carnivores
What is the electron transport chain?
Electrons are transported from reduced coenzymes to oxygen -> water
Regenerates oxidised coenzymes
What are the respiratory complexes found on the inner membrane of mitochondria?
I-IV + coenzyme Q and cytochrome C
Proton pumps which use energy from each redox reaction to pump hydrogen ions from the matrix to the intermembrane space
What is the result of pumping hydrogen into the intermembrane space?
Proton gradient - Creates positive electrochemical potential
What is the proton gradient used for?
ATP synthase uses the gradient to produce ATP
Oxidative phosphorylation
Oxidative phosphorylation
Regenerates oxidative coenzymes
Oxygen reduced to water
ATP produced from proton gradient
What is respiratory control?
When ADP is low and ATP is high, can turn off whether electrons are transported to oxygen

ADP low/ATP high
ATP synthase stops
Proton gradient builds up
ETS stops
NADH oxidation stops
TCA cycle stops
What is an uncoupling protein?
Can dissipate the proton gradient before it's used for oxidative phosphorylation (i.e. energy formation, energy lost as heat instead)
Give an example of a mitochondrial uncoupler
Cyanide, DNP slimming drug