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10 Cards in this Set
- Front
- Back
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the three classifications of IBD
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UC
Crohn's intermittent colitis - which just means we don't now if it's UC or Crohn's |
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symptoms of IBD
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Ab pain
diarrhea wt loss/ failure to grow (in kids) fever family Hx of IBD |
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extraintestinal manifestations of IBD
6 sites name one from each or just get the common ones |
arthritis - periphral or central (axial)
Skin lesions - erythema nodosum, pyoderma gangrenosum eye lesion - uvitis liver lesions - sclerosing cholangitis, cholangiocarcinoma |
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common lab abnormalities in IBD
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anemia - due to terminal ileum dysfunciton or occult blood loss
elevated CRP decreased albumin (negative acute phase reactant, or poor nutrition) fecal leukocytes |
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definition of ulcerative colitis
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mucosal ulceration (limited to mucosa)
rectum always involved inflammation extends in a continuous fashion (good indicator of prognosis) variable amount of colon involved |
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complications of UC
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bleeding
toxic megacolon (toxic refers to pt - fever, dehydration, hypotension) perforation strictures (either from UC or cancer |
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the 2 patterns of Crohn's
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inflammatory
stenotic fistulizing |
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colonic characteristics of Crohn's
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can effect anywhere in GI tract
ulcerations are linear effect all layers of the GI tract so can cause fistulas small bowel involvement and chronic presentation can cause malnutrition |
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distinguishing features of Crohn's
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small bowel involvement
rectal sparing perianal disease skip lesions fistulas granulomas |
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treatment for IBD
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5-ASA agents - Mesalazine (useful in UC)
steroids (useful in short term) immnosuppressives biologics (anti-TNF) surgery (can cure UC, used for complications of Crohn's) |
