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24 Cards in this Set
- Front
- Back
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What is an SSRI?
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Selective Serotonin Reuptake Inhibitor.
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What are SSRIs used for?
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First choice treatment for depression.
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List SSRIs used.
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fluoxetine (Prozac)
citalopram (Celexa) escitalopram oxalate (Lexapro) praoxetine (Paxil) sertrline (Zoloft) |
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What are tricyclics?
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The oldest class of antidepressants. They are still prescribed fairly frequently.
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List Tricyclics used
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amitriptylin (Elavil)
imipramine (Tofranol) doxepin (Sinequan) nortriptyline (Aventyl) |
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What are MAOIs?
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Monoamine oxidase inhibitors. Thery are second or third choice due to their many adverse effects and food-medication interactions.
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List MAOIs used.
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phenelzine (Nardil)
isocarboxazid (Marplan) tranylcypromine (Parnate) |
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What is an atypical antidepressant?
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They are a newer generation of antidepressants. Each one has differing mechanisms
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List the atypicals and their mechanism
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buproprion (Wellbutrin) - inhibits dopamine reuptake (increases dopamine)
venlafaxine (Effexor) inhibits reuptake of seotonin and norepinephrine. mirtazapine (Remeron) increases the release of serotonin and morepinephrine. trazpdpme (Desyrel) inhibits moderate, selective reuptake of serotonin. |
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How long can it take antidepressants for symptom relief?
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1-3 weeks
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How long until full benefits of antidepressants are reached?
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2-3 months.
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Explain fluoxetine and give name
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Prozac - SSRI. Blocks the reuptake of serotonin. This increases the amount within the synaptic space and enhances the effects that can be produced.
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What are the therapeutic uses of fluoxetine?
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Depressive disorders. Anxiety, social phobias, OCD, Generalized Anxiety Disorder, PTSD, Bulemia nervosa
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What are some of the adverse effects of fluoxetine?
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Sexual dysfunction, Weight gain, serotonin syndrome, withdrawal syndrome, hyponatremia, rash, sleepinessq
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What are some contraindications of fluoxetine. Also, what is the brand name.
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Prozac.
DO NOT TAKE WITH MAOIs. Use with caution in patients with liver and renal issues, cardiac disease, Seizures, diabetes, ulcers, or a Hx of GI bleeds. |
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What may happen if a patient on Warfarin takes fluoxetine?
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The Warfarin that is bound to proteins, may be separated from those proteins. This will increase the amount of Warfarin that is circulating.
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If there is an increased amount of Warfarin in system, what should a nurse monitor for?
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Increased PT/INR. Potential bleeding. A dosage adjustment may be required.
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Should fluoxetine be taken with, or without, meals?
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With meals and daily.
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Older adults may experience hyponatremia. What can a nurse do?
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Advise client and monitor sodium levels.
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What is the brand name for amitriptyline, and what is the pharmacological action?
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Elavil - amitriptyline blocks the reuptake of monoamine neurotransmitters norepinephrine and serotonin in the synaptic space. Thereby intensifying the effects produced.
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What are the therapeutic uses of amitriptyline?
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Dpressive disorders and the depressive episodes of bipolar disorders.
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What are some adverse effects of amitriptyline?
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Orthostatic hypertension, anticholinergic effects, cardiac toxicity, sedation.
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What are anticholinergic effects?
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Dry mouth, blurred vision, photophobia, acute urinary retention, constipation, tachycardia.
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What are some contraindications of amitriptyline?
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It is a pregnancy class C medication.
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