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48 Cards in this Set
- Front
- Back
Sleep complaints usually fall into what 4 categories
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-Difficulty initiating/staying asleep (insomnia)
-Difficulty staying awake during the day (hypersomnia) -Abnormal movements/behaviors during sleep (parasomnia) -Timing of sleep (circadian rhythm disorders) |
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What is a key element in the sleep history
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Sleep diary
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Do sleep complaints need to be managed by a non-specialist
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No
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what conditions require a referral to a sleep disorder center
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-Sleep apnea
-Limb movements during sleep -Narcolepsy -Parasomnias w/ potential for injury -Intractable insomnia |
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Recording the pt's sleep overnight in the sleep lab is referred as
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Nocturnal polysomnography (PSG)
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REM sleep is also called
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Paradoxical sleep
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This stage of sleep is defined by presence of sleep spindles and K complexes.
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Stage 2
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Stage 3 and 4 sleep is also called ____ or ____
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Delta sleep or slow-wave sleep
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What is more common, chronic insomnia or transient difficulty sleeping
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Transient difficulty sleeping
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Diagnosis if this disorder involves c/o difficulty in initiating or maintaining sleep or of nonrestorative sleep for one month
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Chronic insomnia
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T or F: insomnia is more common with age and often associated w/ medical and psychiatric disorders or abuse of ETOH, drugs, and meds
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TRUE
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Primary insomnia in its "pure" form comprises a very small proportion because…
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It most often occurs as a comorbid dx
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What are the most widely used sedative-hypnotics
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Benzodiazepines
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What effects to benzos have on sleep
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-Shortening sleep latency
-Improvement of sleep continuity -Decreased slow-wave sleep -Decreased REM sleep |
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Abuse of benzos is more often associated with simultaneous use of what substances
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ETOH and stimulants
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T or F: short-term use of benzos to treat insomnia nd long-term use to treat anxiety disorders are usually not associated with serious clinical problems
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TRUE
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What drugs are safer, benzodiazepines or barbiturates
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Benzodiazepines
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Small doses of these antidepressants have been helpful in treating insomnia
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Amitryptyline and Trazodone
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Withdrawal from prolonged administration of high dose benzos is associated with:
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-Insomnia
-Anxiety -Seizures -Psychosis -Delirium tremens |
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How can you reduce withdrawal sx of benzos
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Carefully tapering the dose
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Before complete discontinuation of benzos, pt should be kept on what % of initial dose for some days to weeks
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25% of initial dose
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Withdrawal sx from benzos can be treated w/ what drugs
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beta blockers - propranolol
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This condition has many forms, from atypical depression when person sleeps 14 hrs a day to a pt with narcolepsy
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Hypersomnia
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In hypersomnia, it is important to differentiate between what 3 states
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-Fatigue
-General tiredness -Excessive daytime sleepiness (EDS) -MI -Sudden death |
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What is the most common cause of EDS in the general population
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Chronic lack of sleep
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Conditions such as PLMS and obstructive sleep apnea may often present with what chief complaint
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EDS
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In this condition, respiratory drive "shuts off"
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Central sleep apnea
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What is the most common disease that causes EDS
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Obstructive sleep apnea
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What are general risks associated with EDS
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-Fatigue related accidents
-Inc. risk of pulmonary HTN -Right sided heart failure -Stroke -MI -Sudden death |
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Obstructive sleep apnea (OSA) is most common in whom
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Overweight, middle aged men
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T or F: Snoring may disrupt sleep and lead to EDS
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TRUE
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Snoring can be controlled with what procedure
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Laser assisted uvulo-palatoplasty (LAUP)
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Uncontrollable sleep attacks where the pt abruptly falls asleep in inappropriate, embarrassing, and even dangerous situations is called
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Narcolepsy
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Most narcoleptics experience related symptoms including:
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-Cataplexy (sudden loss of muscle tone)
-Hypnagogic hallucinations (dreamlike experiences while falling asleep but not yet asleep) -Sleep paralysis (brief paralysis w/ onset of sleep or wakefulness) |
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T or F: Narcolepsy results from defective REM sleep regulation
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TRUE
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What is the treatment of OSA
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-Nasal continuous positive airway pressure (NCPAP)
-Bilevel positive airway pressure (BiPAP) |
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Although some narcoleptics achieve reasonable control of their sleep attacks by structuring their days w/ scheduled naps, many require stimulants such as:
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-Methylphenidate
-Pemoline -Modafinil |
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Unusual events or behaviors occurring either during sleep or during sleep-wake transitions are called:
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Parasomnias
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Parasomnias associaed w/NREM sleep include
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-Sleep terrors
-sleepwalking -sleep bruxism -Confusional arousals |
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Parasomnias associated w/ REM sleep include:
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-Nightmares
-Sleep paralysis |
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What is another name for Jet Leg
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Asynchronosis
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Does eastward travel or westward travel take longer to adjust to and why
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Eastward due to a phase ADVANCE (of the biological clock)
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Alcohol initially increases _____ sleep and decreases _____ sleep
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(increases) Slow wave sleep; (decreases) REM sleep
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T or F: ETOH may exacerbate sleep-related respiratory disorders by potentiating sleep-related atonia during sleep
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TRUE
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Heavy alcohol dependence is associated w/ this sleep disorder
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Chronic Insomnia
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T or F: Alcohol induced sleep is usually characterized by shortened and framented sleep
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TRUE
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Benzos exhibit cross-tolerance with this substance, bearing the risk of abuse, and not likely to be helpful on a long-term basis
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Alcohol
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In the treatment of alcohol related insomnia, sedating antidepressants such as ___, ___, and ___ might be administered at low dosaged, but their therapeutic value has not been evaluated
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-Doxepin
-Trazodone -Amitriptyline |