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66 Cards in this Set

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How many people with serious mental illness have a substance use disorder at some point in their lives?
Approximately 50% of people

55% of schizophrenic clients and 62% of bipolar clients had a comorbid substance use disorder
clients with comorbid mental illness or dual diagnosis often experience more..?
experience more severe and chronic medical, social, and emotional problems. Because they have 2 or more disorders they are vulnerable to both substance abuse relapse and worsening of psychiatric problems.
Substance abuse relapse leads to
psychiatric decompensation, and worsening of psychiatric problems often leads to substance abuse relapse.
Examples of common dual disorders are:
Common examples of dual disorders include the combination of major depression with cocaine addiction, alcohol addiction with general anxiety disorders, alcoholism and polydrug addiction with schizophrenia, and borderline ppd with episodic polydrug abuse
What is the most prevalent of the substance abuse disorders?
Alcohol abuse.
Therefore, alcohol related medical problems are the comorbidities most commonly seen in medical settings. Alcohol can effect all organs, in particular the
CNS: Wernicke’s encephalopathy and Korsakoff’s psychosis (lack of vit B).
GI system (esophagitis, gastritis, pencreatitis, alcoholic hepatitis, and cirrhosis of the liver.
Effects of cocaine users:
experience extreme weight loss and malnutrition, MIs, and stroke
IV drug users have severe...?
infections and sclerosing of veins.
Intranasal users have..?
sinusitis and perforated nasal septum
Biological Theory of chemical dependency:
Substance use problems seem to run in families. Alcoholism is 3-4 times more likely to occur in children of alcoholic parents than in children of non-alcoholic parents
Biological theories of chemical dependancy:
It has been demonstrated more recently that alcohol and drug use has specific effects on selected neurotransmitter systems.
1. Opiods:
2. Alcohol and CNS depressants:
3. Cocaine and amphetamines:
1. Opiods: act on opioid receptors
2. Alcohol and CNS depressants: act on GABA receptors. This findings help to explain the addictive and cross tolerance effects that occur when the use of alcohol is combined with use of barbiturates and benzodiazepines
3. Cocaine and amphetamines: act on the dopamine system.
Psychological Theories of chemical dependacy:
Although no known addictive personality type exists, associated psychodynamic factors have been identified, including the following:
lack of tolerance for frustration and pain,
lack of success in life,
lack of affectionate and meaningful relationships,
low self-esteem,
lack of self-regard,
risk taking propensity.
Psychodynamic Theories view substance use as a? (3)
defense against anxious impulses,
a form of oral regression (dependency),
or self-medication for depression
Persons who are polysubstance abusers are more likely to report..?
Persons who are polysubstance abusers are more likely to report an unstable childhood and self-medication than are persons who abuse alcohol.
What therapy focuses on positive reinforcement effects of drug-seeking behavior?
Behavioral therapy
What is a need for higher doses to achieve the desired effect?
Tolerance
What occurs after a long period of continued use, so that stopping or reducing use results in specific physical and psychological s/s?
Withdrawal
Phenomenons frequently associated with substance abuse are (5)
Tolerance
Withdrawal
flashbacks,
synergistic effects,
antagonistic effects.
What are transitory recurrences of perceptual disturbance caused by person’s earlier hallucinogenic drug use when he/she is in a drug-free state
Flashbacks
Flashbacks can be experienced as:
visual distortions,
time expansion,
loss of ego boundaries
intense emotions
Flashbacks are typically like what?
Often flashbacks are mild and pleasant, but other times individuals experience repeated recurrences of frightening images or thoughts.
What drugs taken together have serious synergistic effects and intensify or prolong effects of drug?
1. alcohol and benzodiazepine,
2. alcohol and opiate
3. alcohol and barbiturates

Taking two of these drugs results in far greater CNS depression than the simple sum of the effects of each drug.
Many people combine drugs to weaken or inhibit the effect of one of the drugs (I.e. for antagonistic effects).

What is an example of this?
1. Cocaine with heroin(speedball). Heroin (CNS depressant) is meant to soften the intense letdown of withdrawal from cocaine (CNS stimulant).
What is an opiate antagonist that is often given to people who have overdosed on heroin to reverse respiratory and CNS depression?
Naloxone (Narcan)
Assessment:Current alcohol and/or other drug problems can be detected by asking two questions that are easily integrated into a clinical interview, which are:
1. In the last year, have you ever got drunk or used drugs more than you meant to?
2. Have you felt you wanted or needed to cut down on your drinking or drug use in the last year?

Ask specific questions. Specific names of drugs, route, quantity, time of last use, and usual pattern of use.
Assessment: Responses that serve as red flags indicating the need for further assessment are:
1. rationalizations (“you’d use dope to if. . . );
2. automatic responses as if the question were predicted,
3. slow, prolonged responses, as if the person were being careful about what to say.
If the person is not able to provide a drug hx assess for indications for substance abuse, such as:
1. dilated or constricted pupils,
2. abnormal v/s,
3. needle marks,
4. tremors, and
5. alcohol on the breath.
Assessment: There is a consistent and significant association between alcohol and/or drug use and ..what?
the occurrence of injury.

significant association between alcohol and/or drug use and the occurrence of injury.
Substance abuse can go undetected in those who are:
1. depressed,
2. suicidal, or
3. anxious unless a thorough hx is taken.
Assessing the psychological changes: Certain psychological characteristics are associated with substance abuse, like:
1. denial,
2. depression,
3. low self-esteem,
4. dependency, and
5. hopelessness.

It is often hard to determine which comes first, psychological changes or substance abuse
Some people self-medicate to cope with psychiatric symptoms. For these people, symptoms of psychological difficulty.... do what?
For these people, symptoms of psychological difficulty remain, even after months of abuse.
Assessment: Substance abusing people are threatened on many levels in their interactions with nurses.
How are they? #1
1. They are acutely aware that not all nurses are equally willing to care for addicted people, and in fact, many clients have experienced instances of rejection in past encounters with nursing personnel.
Assessment: Substance abusing people are threatened on many levels in their interactions with nurses.
How are they? #2
2. Substance abusers may be anxious about recovering because to do so they must give up the substance they think they need to survive.
Assessment: Substance abusing people are threatened on many levels in their interactions with nurses.
How are they? #3
3. Addiction is a chronic relapsing condition. In fact, relapse is one of the criteria for diagnosing addiction. Most addicts tried recovery at least once before and have experienced relapse. As a result, many become discouraged about their chances of ever succeeding.
Assessment: Substance abusing people are threatened on many levels in their interactions with nurses.
how? --Summary of all three
1. past rejection of care from nurses.
2. they think they need the substance to survive.
3. They have tried and failed before, and are discouraged.
These three concerns have what kind of effect on the patient?
These concerns can threaten the addict’s sense of security and sense of self, increasing anxiety levels.
How do addicts protect themselves from these feelings?
To protect against these feelings, the addict establishes a predictable defensive style with various defense mechanisms (3), thought processes (2), and behaviors (3) like:
1. Defense mechanisms: denial, projection, rationalization
2. thought processes: all or non thinking, selective attention.
3. behaviors: conflict minimization and avoidance, passivity, and manipulation.
Substance abuser is not able to give up these defenses until:
Substance abuser is not able to give up these defenses until more functional coping styles are learned.
Assessing s/s of intoxication:
CNS depressant drugs please see text (table 27-2, pg. 553). Withdrawal rxns to alcohol and other CNS depressants are associated with severe morbidity and mortality, unlike withdrawal from other drugs.
Alcohol withdrawal: The early s/s of withdrawal develop within ?
a few hours after cessation or reduction of alcohol (ethanol) intake.
Alcohol withdrawal: The early s/s of withdrawal peak after?
24-48 hours and then rapidly and dramatically disappear, unless the withdrawal progresses to delirium.
Alcohol withdrawal: the person may appear...?
The person may appear hyper-alert, jerky movements, experience illusions, hallucinations, shakiness, grand mal seizures.
Alcohol withdrawal: what kind of environment can the nurse create for the addict that will be therapeutic?
1. A kind, warm and supportive environment by the nurse can decrease anxiety and provide a sense of security.
2. Orient them to time and place.
3. Encourage family members to stay with them (one at a time).
Alcohol withdrawal: If a person is argumentative, hostile, or demanding it is often because of ?
What can the nurse do?
Often because of deep-seated anxiety and shame. The nurse can help relief and give hope by demonstrating an accepting attitude.
This is considered a medical emergency and can result in death even if treated.
Alcohol Withdrawal Delirium
Death from Alcohol Withdrawal Delirium is usually due to?
due to
1. sepsis,
2. MI,
3. fat embolism,
4. peripheral vascular collapse,
5. electrolyte imbalance, and
6. aspiration pneumonia.
The state of delirium usually peaks in?
peak 2-3 days (48-72 hours) after cessation or reduction of intake (although it can occur later) and lasts 2-3 days.
Alcohol withdrawal s/s
1. anxiety, insomnia, anorexia, and delirium
2. Tachycardia, diaphoresis, High BP
3. Fluctuating level of consciousness (ranging from hyperexcitablity to lethargy)
4. Delusions, paranoid, agitated behavior and fever of 100F). They need immediate medical action.
CNS stimulants (please see text pg. 555, table 27-4). All stimulants accelerate the normal functioning of the body and affect the CNS. Common s/s of stimulant abuse include:
1. dilation of the pupils,
2. dryness of the oronasal cavity, and
3. excessive motor activity.
When a person who has ingested a stimulant experiences:
1. chest pain,
2. irregular pulse and has a
3. hx of heart problems need to be taken to ER immediately.
Chemically Impaired Nurse. Nurses have a WHAT% higher rate of chemical dependency than the general population.
32-50%
Estimates of proportion of practicing nurses who are chemically dependent range from ??%.
range from 10-20%.
Chemically Impaired Nurse: What behaviors would they have?
1. Often they will volunteer to work additional shifts to be nearer to the source of drug.
2. They may spend a lot of time in the bathroom.
3. When they are on duty more clients may complain that their pain is not relieved.
Chemically Impaired Nurse: Intervention is the responsibility of who?
responsibility of the manager and the administration. However, the co-workers need to document the dates and specific times. Some state boards allow them to avoid disciplinary action if they seek tx.

The aim is to:
The aim is to protect pts and to keep the nurse in active practice maybe with limitations.
Chemically Impaired Nurse:
The aim of tx is?
The aim of tx is self-responsibility. Safe detox and referral to an inpatient and outpatient chemical dependency program. Please see the communication guidelines in text, pg. 562.
A useful tool for helping the resistant addict develop a willingness to change in tx is known as
substance-abuse intervention.
Table 27-4, pg. 563.

The concept behind this is that addiction is a ...?
progressive illness and rarely goes into remission without outside help.
Relapses are common during the person’s recovery. The goal of relapse prevention is to ?
To help the client learn from these situations so sobriety can be lengthened. Relapse can result in renewed and refined effort toward change.
Other addict-recovery programs include:
1 self help groups (AA),
2. Al-Anon, Alateen,
3. Twelve step programs (views alcoholism as a disease),
4. outpatient drug-free programs and
5. employee assistance programs.
Psychopharmacology: Alcohol withdrawal tx. Not all people who stop drinking require management. It depends on:
1. llength of time and the amount the client has been drinking,
2. prior hx of withdrawal complications,
3. overall health status.
Psychopharmacology: Alcohol withdrawal tx:
Medication should not be given until ?
the s/s of withdrawal are seen. See text, pg. 568, table 27-9.
What is an agent used for narcotic addiction-is sometimes used in the tx of alcoholism, especially for those with high levels of ??
Naltrexone (Trexan, Revia)
--for those with high levels of craving and somatic symptoms
Naltrexone works by
Works by blocking opiate receptors, thereby interfering with the mechanism of reinforcement and reducing or eliminating the alcohol cravings.
(Antabuse) Disulfiram works by?
creates unpleasant physical effects when alcohol is consumed: facial flushing, swaeting, throbbing h/a, neck pain, tachycardia, respiratory distress, serious decrease in BP, & n/v.

Most effective in early recovery.
What is a synthetic opiate that blocks the craving for and effects of heroin?
Methadone (Dolophine)

How often does it need to be taken?
It has to be taken every day, is highly addicting, and when stopped produces withdrawal.
For methadone to be effective, the client must:
the client must take a dose that will prevent withdrawal symptoms, block drug craving, and block any effects of illicit use of short-acting narcotics.

Should include counseling and job training.
Methadone is the only medication currently approved for the tx of ?
tx of the pregnant opioid addict.
Other Tx for Opioid Addiction:
Please read text, pg 569 on LAAM, Naltroxone, and Clonidine.
Please see workbook pgs. 233-256.