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18 Cards in this Set
- Front
- Back
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Leading cause of disability |
Depressive Disorders |
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How long does it take for antidepressant medications to begin to work? |
Four weeks.
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Four main groups of antidepressants |
1. Tricyclic Antidepressant 2. Selective Serotonin Reuptake Inhibitors 3. Monoamine oxidase inhibitors 4. Atypical Antidepressants |
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6 Medications in the TCA family |
1. amitriptyline 2. imipramine (Tofranil) 3. doxepin (Prudoxin) 4. nortriptyline (Aventyl, Pamelor) 5. amoxapine 6. trimipramine (Surmontil) |
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Expected pharmacological action of TCA's |
Block reuptake of norepinephrine and serotonin which intensifies the effects of the neurotransmitters. |
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Therapeutic uses for TCA's |
Depressive Disorders |
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Other uses for TCA's |
1. Neuropathic pain 2. Fibromyalgia 3. Anxiety disorders 4. Insomnia |
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Adverse effects of TCA's |
1. Orthostatic hypotension 2. Anticholinergic effects 3. Sedation 4. Toxicity 5. Decreased seizure threshold 6. Excessive sweating |
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Amitriptyline is a pregnancy category risk of what? |
Category C |
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Amitriptyline is contraindicated whith patients who have ________ disorders. |
Seizure |
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Medication and Food Interactions with TCA's #6 |
1. MAOIs can cause severe hypertension 2. Antihistamines 3. Direct and Indirect sympathomimetics 4. Alcohol 5. Benzos 6. Opiods |
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MAOI's - Name four medications |
1. phenelzine (Nardil) 2. isocarboxazid (Marplan) 3. tranylcypromine (Parnate) 4. selegiline (Emsam) patch |
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Expected pharmacological action of MAOIs? |
block MAO in the brain, increasing the amount of norepinephrine, dopamine and serotonin. |
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Therapeutic uses for MAOIs? |
Depression and Bulimia Nervosa
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Complications/ adverse effects of MAOI's |
CNS stimulation, Orthostatic Hypotension, Hypertensive crisis resulting from tyramine, local rash from patch.
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Phenelzine is a category ____ pregnancy? |
C category. |
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MAOI's are contraindicated in clients taking ______. |
SSRIs |
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Transdermal selegiline is contraindicated for clients taking, _______________- |
carbamazepine (Tegretol), oxcarbazepine (Trileptal), will increase blood levels. |
