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38 Cards in this Set

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It is no longer necessary to have all three criteria: ___, ___, and ___
for dependence.
tolerance, withdrawal, compulsion
CNS depressants:

___, ____, ____, ____
alcohol, sedatives, hypnotics, anxiety agents
Opioids are known as ___.
narcotics
Stimulants: ___, ___
cocaine, amphetamines
Hallucinogens: ___, ___
LSD, PCP
What syndrome is seen in chronic alcoholics?
Korsakoff's syndrome
Wernicke's encephalopathy:

1. Symptoms: ___, ___, ___, ___

2. Caused by ___ deficiency

3. Seen with ___

4. May coexist with ___
1. double vision, involuntary and rapid eye movements, lack of muscular coordination, mild or severely decreased mental function

2. thiamine

3. chronic alcoholism

4. Korsakoff's syndrome
FACT:
6 GI effects of alcohol
1. cirrhosis
2. pancreatitis
3. gastritis/ulcer/GI bleeding
4. inflammatory processes with malabsorption
5. esophageal varices/rupture
6. vitamin B, magnesium and thiamine deficiencies
Overdose of alcohol can cause ___, ___, ___.
coma, respiratory depression, aspiration
___ decrease symptoms and prevent seizures by preventing CNS hyperexcitability.
Benzodiazepines
2 common benzodiazepines?
1. Valium
2. Ativan
___ is taken in rehabilitation treatment program for alcohol. It inhibits aldehyde dehydrogenase causing increase of acetaldehyde if ETOH is ingested.
Antabuse (disulfiram)
2 types of sedatives/hypnotics/anti-anxiety agents?
1. barbiturates
2. benzodiazapines
Effects of sedatives/hyponotics/anti-anxiety agents?
-drowsiness, sedated appearance
-lack of coordination
-euphoria
-labile emotions
-irritability, anxiety
-impaired attention
-working memory loss
2 antidotes for benzodiazapines?
1. Anexate
2. Romazicon
2 designer drugs that are sedatives/hypnotics/anti-anxiety agents?
1. Rohypnol
2. GHB
Examples of opioids:
-morphine
-heroin
-codeine
-dilaudid
-demerol
-percocet
-vicodin
Effects of opioids:
-respiratory depression
-suppresses cough
-inhibits GI motility
-
Withdrawal symptoms of opioids:
-craving
-muscle aches, backaches,
-severe abdominal cramps, diarrhea
-watery eyes, runny nose, yawning
-tremors
-chills, sweating
-crawling sensation on skin
Symptoms of opioid overdose:
-clammy skin
-shallow respirations
-pinpoint pupils (may be dilated with hypoxia)
-death from respiratory depression or pulmonary edema
___ is a given to reverse respiratory depression and coma caused by opioids.
narcan
Complications of cocaine:
-constriction of coronary and cerebral vessels, leading to cardiac and cerebral infarcts
-loss of sense of smell
-pulmonary damage
-hepatitis
Speedballing is cocaine mixed with ___ and injected IV.
heroin
Space-basing is crack cocaine with ___.
PCP
Withdrawal symptoms of cocaine:
-severe craving
-depression
-fatigue, irritability
-vivid, unpleasant dreams
Symptoms of cocaine overdose:
-euphoria, grandiosity, anger, combativeness, impaired judgment
-tachycardia, cardiac arrhythmias, elevated BP
-perspiration, chills
-N/V
-seizures, respiratory depression
-hyperpyrexia
-death
Nystagmus may indicate ___ in alcoholism.
Wernicke's encephalopathy
Alcohol withdrawal delerium is characterized by:
-confusion, disorientation, hallucinations
-tachycardia
-hypertension or hypotension
-extreme tremors
-agitation
-diaphoresis
-fever
-death may result from cardiovascular collapse or hyperthermia
This drug is taken in rehab treatment program for alcoholism.
antabuse
Sedatives/hypnotics/
antianxiety agents ehances action of ___ in limbic system.
GABA
8 opioids:
-morphine
-heroin
-codeine
-Dilaudid
-Demerol
-methadone
-Percocet
-Vicodin
Symptoms of opioid withdrawal:
-craving
-muscle aches, backaches
-severe abdominal cramps, diarrhea
-watery eyes, runny nose, yawning
-tremors
-chills, sweating
-crawling sensation on skin
Symptoms of opioid overdose:
-clammy skin
-shallow respirations
-pinpoint pupils (may be dilated withy hypoxia)
-death from respiratory depression or irreversible pulmonary edema
___, a narcotic antagonist, is given to reverse respiratory depression.
narcan
Cocaine binds to DA transporters resulting in accumulation of DA.
cocaine
Complications of cocaine:
-Constriction of coronary and cerebral vessels which can cause cardiac and cerebral infarcts
Withdrawal symptoms of cocaine:
-severe craving
-depression
-fatigue, irritability
-vivid, unpleasant dreams
Cocaine overdose:
-euphoria, grandiosity, anger, combativeness, impaired judgment
-tachycardia, cardiac arrhythmias, elevated BP
-perspiration, chills
-N/V
-seizures, respiratory depression
-hyperpyrexia
-death