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25 Cards in this Set

  • Front
  • Back

Primary amenorrhea

Menarche has never occurred but patient is 16+

Secondary amenorrhea

Loss of menstruation for 3 consecutive months or more

Most common cause of ovarian insufficiency

Turner syndrome

Mullerian agenesis

Failure of uterus, Fallopian tubes and vagina to develop

Hypothalamic dysfunction

Leads to secondary amenorrhea



Excessive stress, excessive weight loss, excessive exercise, eating disorder



Suppresses entire ovarian axis


Low levels of fsh and lh

Hyperprolactinemia

Side effect of dopamine lowering meds, pituitary tumor and hypothyroidism

FSH > 40 on two occasions

Confirms ovarian failure in younger patients

Tx of premature ovarian failure

Hormones until normal age of menopause to reduce risk of osteoporosis and heart disease

Rotterdam criteria

Clinical or lab hyperandrogenism


Oligo-ovulation or anovulation


Polycystic ovaries

Total testosterone >50

Diagnostic of PCOS

Common findings in PCOS

Obesity


Central adiposity


Insulin resistance


Acanthodians nigricans


Skin tags and acne


Abnormal LH:FSH ratio

Common cause of infertility

PCOS

PCOS treatment

Weight loss


Combined contraceptives


Metformin


Spironolactone - for hirsutism


Clomiphene- induce ovulation

Menorrhagia

Menses that last 8+ days or is gushing


Causes of menorrhagia

Fibroids


Adenomyosis


Endometrial hyperplasia


Von willebrands


Thrombocytopenia

Metrorrhagia

Irregular menstrual cycles


Due to oligo-ovulation



Regular menstrual cycles with spotting

Anovulatory pattern

Thyroid dysfunction


PCOS


Hyperprolactinemia


Uncontrolled DM


Hypothalamic dysfunction


First 1-2 yrs after menarche


Pregnancy

Ovulating pattern but excessive flow

Thyroid dysfunction


Coagulation defects


Fibroids


Advanced liver disease

Tests ordered to evaluate menstrual irregularities

Pregnancy


TSH


Prolactin level

Tests ordered to evaluate menstrual irregularities

Pregnancy


TSH


Prolactin level

Endometrial hyperplasia

Simple proliferation turns to abnormal proliferation that involves glandular and stromal elements of endometrium

Endogenous estrogen

Obese women


Excess adipose tissue


Seen in PCOS

Endogenous estrogen

Obese women


Excess adipose tissue


Seen in PCOS

Exogenous estrogen

Estrogen hormone replacement therapy without progesterone



Seen in menopausal and perimenopausal women

Atypical hyperplasia

Changes in cellular structure of endometrial cells