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30 Cards in this Set

  • Front
  • Back

what are the desired outcomes in treating menopause?

alleviate menopausal symptoms


improve quality of life


minimize adverse effects of therapy

what things should you screen for before you recommend a therapy?

CHD risk


breast cancer


hysterectomy

what type of nonpharmacological therapies can you offer for menopause?

smoking cesation, limit alchohol and caffeine, limit hot beverages and spicy foods

how can you treat dyspareunia?

painful sex- use water based lubricants

when would you use topical estrogen?




would you ever need a progestin?

if no vasomotor symptoms andvulvovaginal atrophy




use progestin if its a high dose of estrogen, the progestin would be oral

when should you consider nonhormonal therapy for vasomtor symtoms?




how often do you asses HRT or ERT therapy?

if patient is not interested in hrt or if they hit a contraindication, chd, or breast cancer




6-12 months

what are the benefits of HRT in menopause?




what is an alternative to using HRT for osteoporosis?

effective for treatment of vasomotor symptoms, treats vulvovaginal atrophy, prevents osteoporosis, may lower colon cancer




bisphosphonates



what are the risks of HRT?

cardiovascular disease, breast cancer, venous thromboembolism

what should a women with an intact utureus get if considering HRT?




why?

progestin and estrogen




to decrease risk of endometrial hyperplasia or cancer

what are the benefits of transdermal products

good if high LDL, LFT abnormalities, adherence, possibly less vte compared to oral

what are the contraindications to HRT?

CVD like MI or stroke, breast cancer, DVT or history of, genital bleeding, liver disease, estrogen dependent cancer, pregnancy

what are some common side effects of estrogens?




serious side effects?

nausea, headache, bloating




stroke, VTE, breast cancer

what are some common side effects of progestins?




serious side effects?

nausea, headache, weight gain




VTE decreased BMD

describe the administration in cyclic hrt




is their withdrawal bleeding?

estrogen daily and progestin for days 15-28 with estrogen




yes, period returns

describe the adminsitration in a continuous hrt




is there withdrawal bleeding?




how long until spotting resolves?

estrogen and progestin daily for 28 days




not with this one, but there is spotting




6-12 months

if a patient is taking a COC and experineces bleeding, what can you do?

reduce estrogen dose and/or increase progestin dose

how often should you asses a patient on birth control?




what are the non hormonal therapies for hot flushes?




what treatments really arent used?

every 6-12 months




paroxetine 7.5 mg, clonidine, gabapentin




isoflavones, black cohosh, vitamin E

when would you use osphena?




is it oral or topical?




what are some of the risks?

after patient fails lubircant or topical estrogen or who doest want touse vaginal estrogen




oral




endometrial cancer w/ estrogens alone, cva and dvt

what should you monitor in a patient taking COC?

symptoms, breakthrough bleeding, could check BP, lipids, TSH, breast exam

what are the goals of coc?

prevent pregnancy, regulate menstrual cycle, reduce premenstrual symptoms, treat acne

are monophasic or biphasic/triphasic regimens better?




is there a difference between drospirenone and levo?

no evidence




more vte in drospirenone

what are some of the non contraceptive benefits of COCs?

reduction in endometrial cancer, ovarian cancer, improved regulation of menstruation, prevention of breast and ovarian cysts, reduce risk of pelvic inflammatory disease, improve ancne

what are some of the risks of COC

STD, hypertension, vte, glucose intolerance, breast cancer, cervical cancer, gallbladder disease

what are the 3 ways you can initiate a COC?




which ones should you use a back up method?

first day of period, no back up




quick start aka the day you pick up rx, back up




start 1st sunday following period, back up for 7 days

contraindications for cocs?

heavy smoker, liver disease, vte, stroke, breask cancer, uterine bleeding

what are the side effects of estrogen excess?




how do you fix this

nausesa, weight gain, headache, dysmenorrhea, edema




decrease estrogen, use nsaid for dysmenorrhea

what are side effects of estrogen deficiency?




how do you fix it?

wasomotor, early cycle days 1-9 break through bleeding and spotting, amenorrhea




increase estrogen

what are the symptoms of progestin excess?




decrease progestin

increased appetite, weight gain, bloating, ance, depression




decrease progestin content

what are the symptoms of progestin defieincy?

dymenorrhea or late cycle day 10-21 breakthrough bleeding and spotting




increase progestin, nsaid for dsymenorrhea

what are some early warning signs of COCs?

abdominal pain, chest pain, headaches, eye problems, leg pain