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9 Cards in this Set
- Front
- Back
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Define Equilibrium potential
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A unique potential difference created to oppose the concentration gradient
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The Nerst equation for Sodium
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ENa = Rt/zf x In [Na]o/[Na]i
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The electrochemical gradient
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accounts for concentration difference of the ions and its tendency to diffuse across the membrane
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Why is resting membrane potential ~ -60mV
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K membrane potential is -90mV the membrane has a greater permeability for potassium ions creating the negative value
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Indirect significance of the NaKATPase
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maintains the distribution of sodium and potassium ions across the membrane
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Contribution of different ions on the membrane potential
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Membrane potential is a compromise between equilibrium potentials the ion with greatest permeability has the largest effect
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Resting channels...
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Non-regulated permanently open the movement of ions depends on their concentration and permeability
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Gated channels...
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Are regulated, an example is voltage gated channels where there openess depends on an action potential
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The nerst equation gives
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A value proportional to the ratio of ions going into and out of the cells
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