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5 Cards in this Set
- Front
- Back
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Pathophysiology
Etiology |
• Cancer of melanocyte (under basal layer)
Risk: Appears mostly on: • fair skinned people who burn easily, • people who have a family history, • people with 3 or more blistering burns before they reach 20, and • if they have actinic keratosis, it is already present |
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Clinical Manifestations
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• Can spontaneously arise or appear from a existing mole that transforms
• Appear as: A- Asymmetrical, B- Borders are irregular, C- Color varies within the mole (Brown, Black, bleeding), D- Diameter of 5mm or larger, E- Enlarging or evolving • Also, appears as: Inflammation surrounding skin (of the mole), possible bleeding, ulceration, itching or tenderness (of the mole) |
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Diagnosis
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• Physical / Skin Examination with History (personal / family)
• Physical Examination of Lymph Nodes • Skin Biopsy and possible • Sentinel Node(s) Biopsy, and/or • Imaging Studies, and/or Blood Tests |
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Treatment
Prognosis |
• Treatment: Surgical removal, Cryotherapy, radiation, imiquimod (drug)
Prognosis: • Stage 1 = 89-95% 5 year survival rate • Stage 5 = 19% • 5 year survival rate • Ulcerated = poor prognosis |
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Prevention
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• Decrease exposure to sunlight (use sunscreen with an SPF of 30** or greater, dress in long sleeve clothing, wear a hat/sunglasses, and stay in the shade as much as possible)
• Keeping an eye on moles using the ABCD and E acronym: A - asymmetrical B - borders are irregular C - colour varies within the mole (brown, black, can even bleed) D - diameter 5 mm or larger usually (but can be small at first!) E - enlarging or evolving (used to be elevation, but not all are raised) |
