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30 Cards in this Set

  • Front
  • Back
benign melanocyitc tumors
cafe au lait macules
melanocytic (nevocellular)nevus
a flat brown to black pigmented spot with INCREASED NUMBERS OF MELANOCYTES in basal cell layer
fancy word for freckle
numerous lightly pigmented macules that darken on exposure to sun, with the SAME NUMBER of melanocytes, but INCREASED AMOUNTS OF MELANIN
presence of more than 6 cafe au lait macules exceeding 1.5 cm each suggests
three classification of nevi
Spitz nevus
special nevus
sindle and epithelioid cell nevus
slightly elevated deep blue or black lesion with dendritic melanocytes in dermis
blue nevus
clinical findings of melanoma
assymetry, border, color, diameter
first stage of malignant melanoma
abnormal proliferation of melanocytes WITHIN THE EPIDERMIS (in situ)
second stage of malignant melanoma
radial growth phase, net growth is in radial direction
third stage of malignant melanoma
verticle growth phase
verticle growth o f melanoma signifies
increased biologic potential for mets
classification of malignant melanoma
superficial spreading mal mel (70%)
lentigo maliga mel
nodular mal mel (short radial growth phase, nodule from the start)
acral lentiginous melanoma
most common variety of melanoma ocurring in blacks, hispanics, asians and american indians
acral lentiginous melanoma
single most useful histopathologic indicator of prognosis of melanoma
thickness measurement by breslow
<.75 mm almost never mets
>4.0 mm met over 60%
exposure to tobaki causes
rhinits, pharyngitis, wheezing, eye irritation, asthma, snoring for kids, middle ear effusion
doubles incidence of pneumonia, bronchitis and bronchiolitis in kids
abruptio placentae, placenta previe,
exposure to asbestos causes
asbestosis, mesothelioma, lung cancer
exposure to lead causes
acute: anorxia, constipation, abdomina pain, vomiting, ataxia, clumsiness, convulsions, kids the same but with hyperactivity and then lethargy
chronic: non specific, aches and pains, kids have neuropathy and slowing of development
exposure to volatile agents
eyes, nose, throat irritation
headache, skin, dyspnea, DECLINE IN SERUM CHOLINESTERASE, nauseua, emesis, epistaxis, fatigue
exposure to organophosphate insecticides,
cholinesterase inhibitors
unopposed cholinergic stimulation
salivation, lacrimation, diarrhea, N/V, LOC, bradycardia, seizures, resp depression
targets lungs
tobacco, radiation inhaled, asbestos,
targets liver
iron, zinc
targets kidney
cadmium, chromium, aluminum,
targets hetaopoiesis
arsenic, zinc, lead
targets nervous system
arsenic (PNS), mercury, iron, lead, pyrethroids pesticide (CNS)
Dx of lead toxicity
whole blood level, versus assesing whole body burden
Tx of lead toxicity
chelation and rebound
which type of asbestose is BAD
amphibole because of long slender shape can get in
serpentine cant
treatment of organophosphate toxicity
oxygen and atropine