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30 Cards in this Set
- Front
- Back
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benign melanocyitc tumors
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lentigo
cafe au lait macules melanocytic (nevocellular)nevus |
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a flat brown to black pigmented spot with INCREASED NUMBERS OF MELANOCYTES in basal cell layer
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lentigo
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fancy word for freckle
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ephelis
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numerous lightly pigmented macules that darken on exposure to sun, with the SAME NUMBER of melanocytes, but INCREASED AMOUNTS OF MELANIN
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ephelis
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presence of more than 6 cafe au lait macules exceeding 1.5 cm each suggests
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neurofibromatosis
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three classification of nevi
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junctional
compound intradermal |
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Spitz nevus
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special nevus
sindle and epithelioid cell nevus |
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slightly elevated deep blue or black lesion with dendritic melanocytes in dermis
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blue nevus
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clinical findings of melanoma
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ABCD
assymetry, border, color, diameter |
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first stage of malignant melanoma
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abnormal proliferation of melanocytes WITHIN THE EPIDERMIS (in situ)
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second stage of malignant melanoma
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radial growth phase, net growth is in radial direction
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third stage of malignant melanoma
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verticle growth phase
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verticle growth o f melanoma signifies
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increased biologic potential for mets
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classification of malignant melanoma
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superficial spreading mal mel (70%)
lentigo maliga mel nodular mal mel (short radial growth phase, nodule from the start) acral lentiginous melanoma |
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most common variety of melanoma ocurring in blacks, hispanics, asians and american indians
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acral lentiginous melanoma
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single most useful histopathologic indicator of prognosis of melanoma
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thickness measurement by breslow
<.75 mm almost never mets >4.0 mm met over 60% |
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exposure to tobaki causes
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rhinits, pharyngitis, wheezing, eye irritation, asthma, snoring for kids, middle ear effusion
doubles incidence of pneumonia, bronchitis and bronchiolitis in kids abruptio placentae, placenta previe, |
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exposure to asbestos causes
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asbestosis, mesothelioma, lung cancer
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exposure to lead causes
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acute: anorxia, constipation, abdomina pain, vomiting, ataxia, clumsiness, convulsions, kids the same but with hyperactivity and then lethargy
chronic: non specific, aches and pains, kids have neuropathy and slowing of development |
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exposure to volatile agents
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eyes, nose, throat irritation
headache, skin, dyspnea, DECLINE IN SERUM CHOLINESTERASE, nauseua, emesis, epistaxis, fatigue |
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exposure to organophosphate insecticides,
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cholinesterase inhibitors
unopposed cholinergic stimulation salivation, lacrimation, diarrhea, N/V, LOC, bradycardia, seizures, resp depression |
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targets lungs
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tobacco, radiation inhaled, asbestos,
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targets liver
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iron, zinc
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targets kidney
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cadmium, chromium, aluminum,
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targets hetaopoiesis
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arsenic, zinc, lead
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targets nervous system
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arsenic (PNS), mercury, iron, lead, pyrethroids pesticide (CNS)
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Dx of lead toxicity
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whole blood level, versus assesing whole body burden
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Tx of lead toxicity
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chelation and rebound
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which type of asbestose is BAD
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amphibole because of long slender shape can get in
serpentine cant |
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treatment of organophosphate toxicity
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oxygen and atropine
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