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957 Cards in this Set
- Front
- Back
Next step if elevated anion gap
|
Get ABG
|
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How would you manage pulmonary edema from systolic heart failure if lasix and nitro didn’t work
|
Use an inotrope: dobutamine > reduces pre load and forces blood into vasculature
|
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Elevated urine coporphyrins dx
|
Rotor syndrome
|
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How to tell the difference between gilberts and rotor/dubin johns
|
Gilberts is unconjugated, rotor/dj are primarily conjugated
|
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When is mitral stenosis valve repaired with ballon
|
Area of valve <1.5
|
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What is sipple syndrome
|
MEN2A
|
|
MEN 2A triad
|
Medullary
Pheo PTH |
|
MEN2B triad
|
Medullary
Pheo Skin neuromas |
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MEN1 TRIAD
|
Pituitary
Parathyroid Pancreas |
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How does amiodarone affect warfarin levels
|
Increases the levels
|
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Major cause of morbity and death in polycythemia vera
|
Thrombosis
|
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Back pain that is relieved by sitting forward
|
Spinal stenosis
|
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Severe mitral stenosis with evidence of regurg tx
|
Valve replacement
|
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Treatment of acute ulcerative colitits
|
Topical mesalamine derivatives
|
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You are thinking VWF deficinecy but there is no correction with normal plasma
|
Bernard soulier
|
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What tests will yield normal platelet aggregation in bernarnd soulier
|
1. ADP
2. Epinephrine |
|
What is the tx in stable WPW
|
First line : procainamide
Second: amiodarone |
|
How to tell the difference between DIC and TTP
l |
DIC ptt and pt are elevated
Ttp ptt and pt are normal |
|
Abx Tx for diverticulitis
|
Quinolone with metro
|
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Cheapest way to test for eradication of h pylori
|
Urea breath
|
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Sun exposed blistering of skin dx:
|
Porphyria cutanea tardea
|
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Anemia, jaundice, splenomegaly triad dx
|
Hereditary sphero
|
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Treatment for ttp:
|
Plasampheresis to remove adams3 antibodies
|
|
Anemia, low platelets, shistocytes, normal pt, ptt
|
Ttp
|
|
Anemia, low platelets, shistocytes, elevated pt, ptt
|
Dic
|
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Anemia, low platelets, no shistocytes, normal pt, ptt
|
Itp
|
|
Non alcoholic woman with pleural effusion and ascites dx
|
Meigs syndrome
|
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Hepatomegaly, ascites and abdominal pain in a patient with polycythemia vera. Dx?
|
Budd chiari due to thrombosis of hepatic vein
|
|
tinnitus, decreased hearing, and vertigo
|
menieres
|
|
tinnitues, decreased hearing vertigo, facial weakness, numbness
|
acoustic schwanoma
|
|
65 y.o.
Dull, persistent abdominal pain with radiation to the back 20 lb weight loss in last three months Decreased appetite Exam reveals mid epigastric tenderness Swollen tender calf Blood glucose 280 mg |
pancreatic cancer
|
|
why swollen calf >
|
cancer is hypercoag leading to dvt
|
|
58 y.o. woman - Persistent joint aches affecting hands and hips in a asymmetric
distribution. Pain is aggravated by activity. She notes about 10 mins of morning stiffness relieved by heat and movement |
osteoarthritis
|
|
what is the key point >
|
<10 minutes morning stiffness indicated non inflammatory
|
|
21 y.o. man 4 months low back pain that improves with exercise and does not
improve with rest. Also notes posterior thigh pain. What’s the diagnosis? |
ankylosing sponylitis
|
|
where can the sacroiliac pain be referred to>
|
posterior thigh
|
|
what will xr show:
|
bamboo spine
|
|
key point in ankylosing spondylitis
|
> pain that gets better with excercise.
|
|
what is the best test to order for rheumatoid factor:
|
anti citriulinated protein (anti cccp)
|
|
33 y.o. man presents with recurrent right knee pain and swelling of 4 years
duration. x-ray film shows speckling of the articular cartilage with increased joint space. Joint tap shows pos birefringent, rhonboidal intracellular crystals. Whats the diagnosis? |
pseudogout
|
|
what are the 2p's of pseudogout
|
1. postive bifringent
2. polygon crystals |
|
Older patients > 55, female, fever, anemia, and headaches, next step
|
ESR THEN corticos if elevated
|
|
Adult > 50 years old, Aching & Morning stiffness in neck, shoulders and hip
girdle. No evidence of destructive joint disease. Elevated sed rate. Rheum factor negative. Diagnosis |
polymyalgia rheumatica
key point > hip and shoulder girdle stiffness, RH negative |
|
what vasculitis is pmr associated with:
|
temporal arteritis
|
|
cancer that stains with pap:
|
squamous cell
|
|
peripheral vascular disease, Severe mid abdominal pain 30 mins after eating
|
mesenteric ischemia
|
|
pain out of proportion to exam
|
mesenteric ischemia
|
|
chest pain underwent cardiac cath. 3 Hours later he developed severe mid
abdominal paincomplains of vomiting and diarrhea dx |
mesenteric ischemia due to emboli
|
|
thumbprint sign of axr indicative of
|
ischemic colitis
|
|
45 y.o.with Chronic myelogenous leukemia develops renal failure after
chemotherapy.UA shows crystals. What is the cause of renal failure? |
tumor lysis syndrome
|
|
what type of crystals in urine will you see in tumor lysis
|
uric acid and calcium phosphate
|
|
how would you prevent renal failure due to tumor lysis
|
give allopurinal
|
|
Draining sinus underneath chin – dental extraction of an abscess tooth 6 wks ago
|
actinomyces
what are they famous for > head and neck infection |
|
20 year old woman c/o dysuria, increased urinary frequency, suprapublic pain.
Dipstick negative for nitrites |
staph saprophyticus
|
|
20 year old woman c/o dysuria, increased urinary frequency, suprapublic pain.
Dipstick positive for nitrites |
e coli
|
|
56 y.o. woman whose hobby is gardening Presented with red swelling in right
middlle finger, dx and tx |
sporotrichosis, itraconazole
|
|
dog bite <24 hours after gets with fever swelling dx
|
pasturella
|
|
dog bite >24 hours after gets with fever swelling dx
|
capycytophagia carnivorous
|
|
what 4 organisms are present in a human bite
|
1. Strep
2. Staph 3. Eikenella 4. Fusobacterium |
|
obese pt has hip pain, is able to localize the pain with one finger is is worse when
lying on that side: |
trochanteric bursitis
|
|
shoulder pain but normal shoulder exam should indicate:
|
referred pain to shoulder
|
|
what does xr show in RA?
|
Marginal joint erosions
|
|
Person has bloody diarrhea and arthritis
|
Enteropathic arthritis
|
|
Treatment of lupus nephritis
|
High dose corticos
|
|
What is the leading cause of death associated with dermatomyositis and
polymyositis |
Interstitial lung fibrosis
|
|
How would neuromusclular weakness present on pft
|
Rv increased
Tlc increased fev/fvc normal dlco normal |
|
breathing that worsens when sitting up, better when lying down
|
hepatopulmonary syndrome
|
|
what is the pft finding in vocal cord dysfunction
|
decreased lung volumes
|
|
how to tell difference between pneumonia and pleural effusion on exam
|
tactile fremitus increased in pneumonia
|
|
how to distinguish mesenteric ischemia from ischemia colitis
|
ischemia colitis > due to hypoperfusion > MI or cardiac failure
AMI > emboli and pain out of proportion to exam |
|
best screening test for aperson with cirrhosis for cancer
|
ultrasound now, AFP later
|
|
what two tests confirm primary biliary cirrhosis
|
1. ama
2. way elevated ALK PHOS |
|
most common skin manifestation of IBS (crohsn or uc)
|
erythema nodosum
|
|
thinking viral meningitis, but high WBC, what organism
|
cocksacki
|
|
meningitis with lp pointing towards bacterial, but hx of rodent exposure
|
lymphocytic choriomeningitis
|
|
coved st in V1, v2, V3
|
brugada syndrome
|
|
how to dx radiation colitis
|
flexible sigmoidoscopy
|
|
person with UC, when doy ou do screening colonoscopy
|
after 8-10 years
|
|
cat scratch fever presentation but swollen painful lymph node
|
Yersinia
|
|
how to calculate A-a gradient;
|
alveolar - arterial o2
alveolar o2 = FIo2*(Patm-pH2O) aka 150 - (Co2/.8) arteriolar = the abg O2 level |
|
if person has neurofibromatosis, what other diease is linked to it
|
pheochromocytoma
|
|
what is a side effect of metformin and linezolid , isoniazid
|
metabolic lactic acidosis
|
|
tx for uremia platelet dysfunction
|
ddavp
|
|
how to dx vwf deficiency:
|
1. ristocetin assay
2. vwf multimer distribution |
|
Best choice for uncontrolled diabetes in hospitalized pt
|
Basal and short acting insulin
|
|
What combination of drugs reduces the risk of hypoglycemia in a pt on insulin
|
Basal and short acting combo
|
|
What is required for the dx of dka
|
Blood glucose > 250
Anion gap acidosis Ketones in urine |
|
Woman has hypothyroid, on levothyroxine, at what level do you want the t4 to be
|
1.5x normal
|
|
Sick person with low TSH and free T3 levels with a free T4 level in the normal to
low-normal range, dx |
Sick euthyroid syndrome
Next step Repeat tsh/t4 in 6 weeks |
|
What should you do with an incidentally found adrenal adenoma
|
Investigate it always> VMA/MVA/overnight cortisol
|
|
What is the best screening test for hyperaldo state
|
Aldo:renin ratio (normal 20:to one)
|
|
Pt has osteoporosis, cant tolerate oral bisphos, what to do next
|
Iv biphoshonate
|
|
One day after sustaining a laceration of the right hand. Temp 3.4 HR 110 RR 20
Intense pain, erythema and edema of upper extremity with epidermal necrosis and desquamation. What’s the next step? what is it |
surgical exploration
> necrotizing fascitis due to > group a strep |
|
how to tell primary sclerosing cholangitis from primaru biliary cirrhosis
|
psc - ama negative
pbc -ama postive |
|
25 y.o. woman with recurrent sinopulmonary infection. eceives transfusion for post
partum hemorrhage. and goes into anaphylaxis, dx |
iga deficiency
|
|
Pt with cirrhosis due to hepatitis C developed worsening jaundice, increased ascites,
encephalopathy and vague right upper quadrant pain. CT reveals presence of a large tumor mass in the liver. next test to order |
afp
|
|
what arteries are most commonly involved in htn hemorrhage
|
lenticulostriate
|
|
dizzyness, facial pain, trouble swallowing, dx
|
lateral wallenburg syndrome
|
|
what is the tx for svt
|
1. valsalva
2. carotid massage 3. adenosine/verapimil/beta blocker |
|
68 y.o. unexplained falls (loss of balance while walking), vertical gaze palsy
(blurring of vision) tremor, bradkinesia, rigidity. Diagnosis? |
psp
|
|
how to tell from parkinsons
|
no eye involvement in parkinsons
|
|
flushing, diarrhea, murmur
|
carcinoid syndrome
|
|
Systolic murmur increased on inspiration. No evidence of pulmonary hypertension.
? Likely diagnosis? |
tricuspid regurg
|
|
Sickle cell patient who works as a daycare worker. evelops Temp 38.1 C,
palpitations, dizziness, Hb 6.0 g/dL. Howell jolly bodies and absence of reticulocytes. What is the Diagnosis & likely pathogen? |
transient aplastic crisis due to B19 infection
|
|
acute illness, infiltrate and cavity in left LOWER LOBE >
|
anaerobic abscess
|
|
28 y.o. IV drug user presents with fever, chills, malaise, nausea, headaches. Exam
reveals loud holosytolic murmur. next step; |
1.blood cultures x2
2. echo 3. start antibiotics for endocarditis |
|
non stemi, what antiplatelet to give after
|
1. aspirin
2. plavix |
|
bp 230/140 , optic disk edema, dipstick positve for protein, tx
|
nitroprusside
|
|
first line tx fo r gout
|
indomethiacin
|
|
22 y.o. C/O chronic weakness and fatigue. He notes dizziness when he stands up in
the morning. He notes cold intolerance, facial puffiness, coarsening of his hair and hoarseness. Na 125, K 5.5, Bicarb 25, BUN 22 Glucose 380 and TSH 9.5, Diagnosis? |
polyglandular autoimmuine syndrome type 2
|
|
what disease is specific to PAS type 1
|
hypoparathyroid
and candida |
|
what disease is specific to PAS type 2
|
hypothyroid
no candida |
|
what age group to suspect pas type 1 and 2
|
1 > kids
2 > older than kids |
|
Patient with inflammatory bowl disease develops a pustule on his skin that
progresses to an inflammatory ulcer with ulceration, necrosis and purulence. Diagnosis? What do you expect to find on skin biopsy? |
pyoderma gangrenosum
will see neutrophilic infiltrate |
|
A patient with acute myelogenous leukemia whose disease has been stable
developed tender, inflamed papules, plaques and nodules on her arms and legs. She notes a new lesion occurred at the site of a blood draw. She has also noted irritation of her eyes. She has also developed fever to 39 degrees. Diagnosis? What do you expect to find on skin biopsy. |
dx is > sweet syndrome
biopsy > neutrophilic infiltrate |
|
Sores on lip and scrotum. Photophobia.
Knee pain. Elevated Sed Rate Diagnosis? |
bechet disease
waht is it > vasculitis of all size blood vessels will invovle: 1. eye ulcers 2. mouth/tongue ulcers 3. genital ulcers |
|
left pupil constricts with light on right, no constriction with light on left, dx
|
left central retinal artery occlusion
|
|
50 y.o. presents with 5 yr history of arthralgias who was suspected of having
rheumatoid arthritis. She now notes progressive dyspnea on exertion. On exam she has erythematous patches over the knuckles, a mild malar rash andviolaceous discoloration to the eyelids. Crackles at lung bases. There are no joint deformities. CXR show patchy infiltrates. What antibody do you expect to be in high titer. |
anti ribonucleoprotein
its mixed connective tissue disease = |
|
mononucleosis, he asks when he can return to playing. On exam you detect
no splenomegaly. What do you tell him? |
4 weeks
|
|
what ekg change will you see in a myeloma pt:
|
qt shortneing due to hypercalcemia
|
|
in May a boy scout who went camping in in Oklahoma last week is seen for C/O
fever, severe headache, malaise and nausea and a petechial rash involving palms and soles. What test for Dx before Tx? |
rocky mountain spotted fever - biopsy
Treatment doxy |
|
A sheep and Goat farmer in Upstate NY with recent (2 wks ago) good fortune of
several births of lambs and kids presents with a flu like illness, pneumonia and hepatitis. What zoonotic infection should be considered. |
q fever coxiella burnetti
|
|
`
what are the indications for intubation in asthma |
1. acidosis
2. hypoxemia |
|
patient is younger than 45 years and has bilateral basilar emphysema, what to look for
|
a1at
|
|
what is similar between Cryptogenic organizing pneumonia and idiopathic
pulmonary fibrosis |
- both are in older patients with no smoking or exposure history
|
|
how to tell the difference between COP and IPF
|
COP will be more acute, develops over 2 months or so,
- will basically resemble a pneumonia that hasn’t resolved with tx IPF will be longer course, over months to yerars |
|
Leukocyte/wbc casts indicate what two things
|
Acute interstitial nephritis
pyelonephritis |
|
How to tell blood in urine is from glomerular or other sources
|
Glomerular dysmorphic RBC with casts
Non glomerular regular RBC, no casts Workup in non glomerular : cystoscopy |
|
Treatment of hypercalcemia due to sarcoid
|
Prednisone
|
|
Triad of right ventricle MI
|
. hypotension
2. elevated central venous pressure 3. clear lung fields |
|
what is the tx of right ventricle MI
|
fluids
|
|
what type of heart block is associated with lyme
|
3rd degree
|
|
chronic stable angina that gets worsening symptoms tx
|
increase bb dose
|
|
presence of new murmur after MI could be 2 things:
|
. Acute mitral regurg
2. vsd rupture |
|
treatment of lung abscess
|
zosyn or unasyn
|
|
tx of uncomplicated cystitis in non pregnant woman
|
bactrim
|
|
tx pyelo in non pregnant woman
|
ciprofloxacin
|
|
when to do ppx for mac in aids and
what to give |
<50 , azythromycin
|
|
if a person gets recurrent zoster what do you have to look for
|
hiv
|
|
sinus bradycardian plus sinus arrests dx
|
sick sinus syndrome
|
|
when should dig be added to chf
|
when ejection fraction worsens, stage 3 or 4 ny heart with limitations in activity
|
|
pt has typical chest pain then develops chf like picture, best dx step
|
angio
|
|
what heart murmur will increase p2
|
mitral stenosis
why - increased pulmonary artery pressure |
|
how to dx familial mediterrian fever
|
periods of 1-3 days of fever with serositis (can be mis dx as appendicitis)
|
|
treatment for asymptomatic bacturia in non pregnant woman
|
none
|
|
treatment for asymptomatic bacturia in pregnant woman
|
ampicillin or nitro
|
|
Highly specific test when negative means what
|
Rules disease in
|
|
Highly sensitive test when postive means what
|
Rules disease out
|
|
What is the probability that a positive test result is a true positive result asking for
|
Postive predicitive value
|
|
Postive LR of 2, 5, 10 increase post test odds by how much
|
15%,30%,45% respecitively
|
|
Negative LR of .5,.2,.1 decrease post test odds by how much
|
15%,30%,45% respecitively
|
|
All pts with hemoptysis should receive
|
Ct scan
|
|
Pt with heavy menstrual bleeding tx
|
Medroxyprogesterone
|
|
The next step in the evaluation of this patient with secondary amenorrhea after stopping her oral contraceptive pill is
|
a progestin withdrawal challenge
|
|
progestin withdrawal challenge yields no bleeding, next step
|
ultraasound to assess pevlic anatomy
|
|
abnormal uterine bleeding in pt >35 next step
|
endometrial biopsy
|
|
demarcated, eczematous, crusted, erythematous papulovesicular plaques and excoriations that characteristically are pruritic and involve the antecubital and popliteal fossae and flexural wrists.
|
Atopic dermatitis
|
|
itchy, red, edematous, weepy, and crusted, sometimes with vesicles or bullae
|
alllergic contact dermatitis
|
|
Contact dermatitis can usually be differentiated from cellulitis by the
|
presence of pruritus and the absence of fever
|
|
itchy Lesions that are erythematous, with dry or greasy scales and crusts
|
sebhorric dermatitis
|
|
Erythema with telangiectasias, pustules, and papules
|
Rosacea
|
|
What infection is erythema multiform associated with
|
Hsv
|
|
Treatment of acute herpes zoster
|
oral acyclovir, valacyclovir, or famciclovir
|
|
elderly pt with htn, which drug to start off on
chlorthalidone person found to have bp >160 on two occasions what to start on |
2 drugs!! Ace and diurtetic
|
|
pt with fevers of unknown origin, low cd4 for a while, hv to check for what
|
lymphoma
how: marrow biopsy |
|
sausage veins on fundoscopic exam, increased plasma cells in marrow dx
|
waldenstrom
|
|
person gets transfusion, then develops hypoxemia and respiratory distress, dx
|
transfusion related acute lung injury
|
|
how is trali different form transfusion rx ==>
|
no hypoxemia in a regular transfusion rxn
|
|
what is the tx for dvt in pregnancy
|
heparin until 6 weeks post partum
|
|
sustained v tac without symptoms tx
|
1. Amio
or 2. lidocaine |
|
sustained v tact with symptoms tx
|
synchronized cardiovert
|
|
what type of insulin to give in dka
|
regular
|
|
when do you give k in dka
|
when less than 5.3 and HAVE URINATED
|
|
why do you give dextrose in dka
|
to prevent cerebral edema
|
|
person has mi, 4 weeks later develops jvd, ascites, shortness of breath, dx
|
left ventricle aneurysm
|
|
tx of right ventricle mi
|
fluids
|
|
what are the following in primary hypognonadism
|
LH: increased
FSH: increased Total testosterone: decreased Free testosterone; decreased Sex hormone binding globulin: increased |
|
Hexagonal crystals in ua indicate:
|
Cysteine
|
|
next test if cysteine crystals in urine
|
Cyanide nitroprusside test
|
|
Atypical lymphocytes seen in skin biopsy
|
Either
1. Sezary 2. mycosis fungoides |
|
jvd, hepatomegaly, ascites, lvh with low voltage
|
amyloidosis
|
|
tx of primary amyloidosis
|
steroids and lenolidomide
|
|
transfusion, fever, no hemolysis, dx
|
non allergic transfusion rxt
due to what: cytokines in transfused blood |
|
transfusion, fever, hemolysis, what type of hypersensitivity
|
type 2
|
|
flu or mono like picture, rash two days later, have to look for what
|
hiv
|
|
what is hiv ppx <200 and for what
|
Bactrim or, atovaqunoe, dapsone for PCP
|
|
Hiv ppx <100 and for what
|
Bactrim, or atovaqunoe, dapsone for toxo
|
|
Hiv <50
|
Azithromycin for mac
|
|
Tx for familial mediterrranean fever and to prevent what
|
Colchicine
amyloidosis |
|
tx of uncomplicated cystitis in non pregnant woman
|
bactrim
|
|
tx pyelo in non pregnant woman
|
ciprofloxacin
|
|
treatment of ascaris lumbricosides
|
Mebendazole
|
|
Treatment of chemotherapy related nausea 3 things:
|
1. Zofran
2. dexamethasone 3. fosaprepitant |
|
what is the best test to identify enterameoba histolytica
|
serology not stool
|
|
best dx test for crohns
|
COLONOSCOPy not sigmoidoscopy (terminal ileum is reached by colonoscopy)
|
|
Person with gerd develops trouble swallowing due to what
|
Esophageal stricture
|
|
Best dx test to confirm ebv
|
Heterophil antibody
|
|
What are the indications for cabg
|
1. Left main
2. triple vessel 3. two vessel and diabetic |
|
why are patients with nephrotic syndrome at increased risk for heptic vein thrombosis
|
loss of antithrombin 3 in urine
|
|
is raloxifen safe in hypercoag pts
|
no ==>it increases risk
|
|
pt with cd4 <50 who develops shock, hypotension, hyponatremia, hypokalemia, dx
|
adrenal insufficiency due to CMV, MAC, or Kaposi
|
|
in a person with pe, when is lmw heparin and unfractionated used
|
lmw ==>uncomplicated
unfacrtionates ==>unstable pts |
|
how to tell the difference between pbc and psc if no anti mitochrondrial antibody result is given==>
|
look for signs of associated symptoms
pbc ==>sjogresn ==>dry eyes, dry mouth artificial tears, xanthomas psc ==>ulcerative colitis ==>bloody diarrhea, weight loss, erythema nodosum |
|
fever, cough, non bloody watery diarrhea dx
|
legionella
|
|
tx of legionella and when started
|
ceftriaxone and azithromycin
empirically before culture comes back once diagnosed legionella tx: erythromycin or doxy |
|
microcytic anemia, normal rdw, normal iron
|
thalesemia
|
|
microcytic anemia, high rdw
|
iron def
|
|
necrotic pancreas tx:
|
1. Antibiotics -imipenem/carbapenum
2. bowel rest |
|
if necrotic pancreas doenst improve with rest and abx
|
aspirate the pancreas to rule out superinfection
|
|
low sodium, high potassium , low bicarb, high bun dx
|
addisons
|
|
treatment of cll based on stage
|
stage 0 ==> none
stage 1 ==> none stage 2-4 ==>fludarabine |
|
immunosuppressed person, trouble swallowing, endoscopy shows white plaques
|
candida
|
|
immunosuppressed person, trouble swallowing, endo shows shallow ulcer with volcano
|
hsv
|
|
immunosuppressed person, trouble swallowing, endo shows deep ulcer
|
cmv
|
|
what does foamy macrophages on lung biopsy dx
|
amiodarone toxicity
|
|
B12 in urine after schilling dx
|
Dietary deficiency (able to taken up to be excreted in urine)
|
|
What do you do first in suspected temporal arteritis, prednisone or esr
|
Esr
|
|
Bad Side effect of ptu and methimazole
|
Agranulocytosis (decreased all 3 cell lines)
|
|
Positive ppd in at risk group (physician) next step
|
Isoniazid and b6 for 9 months
|
|
What is barter syndrome and tx
|
Congentical loop diuretic
Nsaid and spironolactone |
|
Person is taking dig and has ekg depression, next step
|
Echo to look for evidence of ischemia
|
|
Pt with non tender palpable mass that is likely cancer, next step
|
EXCISIONAL BIOPSY
|
|
AAA is suspected, next dx step
|
Ultrasound not CT
|
|
when can abd us not be used to rule out aortic dissection
|
obese
|
|
Initial management with aortic dissection pt with htn
|
Labetolol
|
|
Person has early morning pre breakfast glucose level, next step
|
Check at 3am
|
|
Echo with thickened wall and speckled pattern
|
Amyloidosis
|
|
Calcified non enhancing cystic lesions on brain dx and tx
|
Neurocystercosis
Albendazole |
|
Treatment to prevent meningeal relapse in ALL in kids
|
Mtx ppx
|
|
Tx of itp
|
Steroids
if severe: Ivig or rhogam |
|
What is the ddx for pancytopenia:
|
1. Leukemia
2. aplastic anemia 3. b12 deficiency 4. myelofibrosis |
|
older person with elevated wbc with predominant lymphocytes dx
|
chronic lymphocytic leukemia
|
|
next step if a person has a positive fecal blood test
|
colonoscopy
|
|
small incidental nodule in non smoker follow up
|
none
|
|
small incidental nodule in high risk
|
ct in 12 months
|
|
when do we stop screening for prostate cancer
|
75
|
|
tx for mets prostate ca
|
leuprolide
|
|
when do you do colposcopy
|
1. Ascus
and 2. positive hpv for 16 or 18 |
|
how to tell the difference between squamous and melanoma
|
squamous is scaly
|
|
dark blue or berry like lesion on skin
|
nodular melanoma
|
|
rapid growth on skin with nodular crater
|
keratoacanthoma.
|
|
How to tell the difference between vfw deficiency and hemophilia a
|
Bleeding time
Bleeding time is normal in ==>hemophilia a Vfw ==>increased |
|
Common cause of cardo pulmonary disease in sickle cell
|
Pulmonary htn
|
|
Acute treatment in a sickler with acute chest syndrome
|
Red cell exchange
|
|
Slow rising carotid pulse dx
|
Aortic stenosis
|
|
Best diagnostic test for any heart valve issue
|
Coronary angio
|
|
Recurrent uti’s with stone, what is dx
|
Proteus or pseudomonas
|
|
Diabetic with foul smelling otorrhea, red mass lesion in external canal, dx and organsism
|
Malignant external otitis, pseudomonas
|
|
Pt has hyperPTH, gets adenoma removed, week later has decreased ca, dx
|
Hungry bone syndrome
|
|
What is the treatment of aspergillus
|
Vorconazole
|
|
Goal for mitral valve replacement INR
|
2.5-3.5
|
|
thinking alport, first dx test
|
skin biopsy
|
|
3 causes of nighttime chronic cough
|
1 asthma
2. gerd 3. post nasal drip |
|
current tx for hcv
|
peg interferon and ribavirin
|
|
tx for oral thrush
|
swish and spit nystatin
azole troche oral azole |
|
platelet count over one million dx
|
thrombocytosis
- can be primary (jak) or secondary as a reactive measure |
|
fixed split s2, young female, right BBB suggests
|
atrial septal defect
|
|
paradoxical or reverse splitting of S2, what 2 conditions
|
aortic stenosis
hocm |
|
post mi, decreased ekg voltage, equalization of chambers dx
|
cardiac tamponade
|
|
jvd, hypotension, clear lung fields
|
triad of right heart MI
|
|
increased S one heart sound
|
mitral stenosis
|
|
how to calculate vent settting for copd
|
7 times weight in kilo
|
|
how does scleroderma lead to diarrhea
|
dysmotility leads to buildup of bacteria and osmotic diarrhea
|
|
how often to do pap in low risk
|
every 3 years
|
|
steps in the tx of heart failure
|
o2
lasix morphine nitrates dobutamine hydralazine |
|
what will pulmonary cath show in pericarditis and tamponade
|
equlaization of pressure in all 4 chambers (all are about the same)
|
|
most common organisms to cause copd exacerbations
|
strep
h flu moraxella |
|
person post chemo has low neutrophils next step
|
observe no treatment
|
|
perosn post chemo has low neutros and develops fever, tx
|
imipenem/carbapenem
|
|
main complication of radioactive iodine tx
|
hypothyroid
|
|
mass on finger that does not transilluminate and drains fluid
|
tophaceous gout
|
|
person has mi, then develops jvd, rales/wheezing, no murmur, dx
|
chf from mi
|
|
perosn has mi, then gets jvd,clear lungs, pulsus paradoxicus dx
|
cardaic tamponade
|
|
ameobic abcess tx
|
metro NO DRAINAGE
|
|
at what age should dm be screened for
|
45
|
|
at what age in men and women should lipids be checked
|
35, 45 respectively
|
|
how to tell the difference between partially treated bacterial meningitis from aseptic
|
cell count
partially treated bacterial: 20,000 aseptic: only about 2,000 both will have : lymphocyte predominance |
|
what is the preferred agent and alternative for malaria ppx in africa
|
mefloquine is first choice
second is doxy |
|
what is malaria ppx in caribbean
|
chloroquine
|
|
as soon as dx of hyperthyroid is made, what should the pt be started on
|
beta blocker
|
|
what do you treat a person with previous staph infections and now suspecting mrsa pneumonia
|
linezolid
or vanco |
|
first line tx of hus
|
plasmapheresis
|
|
first line tx for ttp
|
plasmapheresis
|
|
person with upper gi bleed but no source can be identified
|
dieulafoy lesion
|
|
most common presentation of hocm
|
dyspnea
|
|
best initial treatment of kidney stone
|
fluids and pain control
|
|
do you give warfarin in HIT
|
NO
|
|
arteriopgraphy shows tortuous pattern of arterioles and pt is smoker, dx
|
thromboangitis obliterans
|
|
initial management of all sarcomas
|
surgery to remove
|
|
high leuk alk phos dx
|
leukemoid reaction
|
|
person undergoes surgery, then develops asymtpomatic jaundice, next step
|
nothing, its post op cholestasis
|
|
most sensitive tests for pheochromocytomas
|
from best to worst
plasma metanephrines urinary metanephrines urinary vma |
|
how to calculate saag
|
serum minus ascites albumin
|
|
what tendon is involved in tennis elbow
|
extensor carpi radialis brevis
|
|
any patient with suspected silicosis should have what ruled out
|
tb
|
|
onion skinning of biliary duct dx
|
psc
|
|
mononuclear PERIDUCTAL infiltrate
|
pbc
|
|
mitral regurg pharm tx, 3 things
|
reduce preload by: diurtetic
reduce afterload: ace ionotrope: dig |
|
what is the ekg finding in PE
|
s1
q3 t3 |
|
fixed split s2 could be due to what 2 things
|
1. ASD
2. RBBB |
|
what injfection can cuase RBBB
|
chagas
|
|
red crusted scaly rash
|
psoriasis
|
|
bowing of long bone, dx
|
pagets
|
|
adrenal mass, labs and workup negative, next step
|
depends on size
>4 -surgery <4: observe |
|
bloody diarrhea with day care
|
shigella
|
|
waxing and waning lymph nodes dx
|
follicular lymphpoma
|
|
blue sclera
|
osteogenesis imperfecta
|
|
low platelets, ezcema, recurrent infections
|
wiskott aldrich
|
|
dipstick positive, high ldh, no red cells in urine, dx
|
myoglobinuria
|
|
most common deficiency in bypass
|
b12
|
|
person has pe, platelts drop week later dx
|
HIT
|
|
howell jolly bodies mean what
|
autosplenectomy
|
|
what is polyglanular syndrome type 1 triad
|
hypo PTH
mouth candida kids |
|
waht is polyglandular syndrome type 2 triad
|
thyroid
adrenal insuffiency no mouth candida adults |
|
nodules at needle stick called what
|
pathergy
|
|
what 3 diseases get pathergy
|
1. bechets
2. pyoderma gangrenosum 3. sweet syndrome |
|
cherry red spot on fundus
|
central retinal artery occlusion
|
|
what drugs are avoided in glaucoma
|
1. anticholinergics: tca, anti h
2. beta agonists |
|
what associations are there with restless leg
|
1. iron deficiency
2. ckd 3. dm |
|
treatment of pulmonary hypertension
|
vasodilator
then calcium channel blocker |
|
solitary vesicle and punched out lesions dx
|
kaposi varicellaform eruption
|
|
hypertension with adrenal mass, should make you think of what 2 conditions
|
pheo
conns |
|
person has elevated alk phos, normal ggt next step
|
bone scan for increased turnover like pagets
|
|
person has elevated alk phos, elevated ggt, next step
|
abd ultrasound
|
|
diarrhea, red eruption on skin, mouth ulcer, increased thirst, increased urination, dx
|
glucagonoma
|
|
how to treat htn in scleroderma pt
|
ace
|
|
firm, red, cord like structures in leg that come and go, dx
|
migratory thrombophlebitis in pancreatic cancer
|
|
what heart findings will you see in pulmonary htn
|
right atrial enlargement
right ventricle enlargement flattening of septa |
|
drug of choice to treat aspiration pneumonia
|
clinda
|
|
someone who has been exposed to hep a next step
|
vaccinate
|
|
bloody vomiting , normal upper gi series likely dx
|
mallory weiss tear
|
|
AIDS patient develops a scaling, oily erythema involving eyebrows, nasolabial folds and chest. Diagnosis?
|
sebhorric keratosis
|
|
55 y.o. man with progressive renal failure (Bun 100, Creatinine 10) presents with burning sensation and pain of the lower extremities. Exam reveals loss of position and vibration sense in the toes and decreased Achilles reflexes bilaterally. Hct 36%. MCV 94. Diagnosis?
|
uremic neuropathy
|
|
50 y.o. evaluated in the ED after twisting his knee while skiing. X-ray show increased bone density, cortical thickening, bowing and over growth.
|
pagets
|
|
elastic skin, hypermobile joints, thin skin
|
ehlors danlos
|
|
30 yo. is seen because of his urine becoming pink and recent DVT. Evaluation reveals HgB 11, indirect bilirubin of 1.1, total 1.5. UA shows dip stick Positive for blood,
0 RBC, LDH 400. combs is negative. What Test next? |
osmotic fragility looking for pnh
|
|
tx for reactive arthritis
|
nsaid
|
|
treatment of suspected bacterial meningits
|
amp if less than one month or >50yrs
vanco ceftriaxone dexamethasone |
|
tx of uncomplicated ebv
|
nsaids or tylenol
|
|
chronic vomiting will produce what pH condition
|
hypochloremic metabolic alkalosis
|
|
what is the most common and worst s/e of azt
|
most common - myopathy and gi
worst - leukopenia/macrocytic anemia |
|
how to tell the difference between graves and exogenous thyroid admin
|
raiu - radioactive iodine uptake
graves: increased factitious: decreased |
|
how long to treat uti in men
|
7 days
|
|
initial tx of aml
|
ara c
plus a rubacin: either dauno/ida |
|
how to tell the difference between cryptosporidium and cmv and mac diarrhea in aids pt
|
crytosporidum: non bloody, acid fast
cmv: bloody mac: dx if nothing else is positive |
|
what drugs must be stopped prior to ekg stress test
|
ones that lower HR
Beta blockers calcium channel blockers |
|
when do you do stress echo instead of ekg
|
left bundle branch block
baseline st elevations/depressions curretnly on dig |
|
more oxygen in right ventricle than right atra post mi dx
|
septal rupture
|
|
acute severe hypotension post mi
|
free wall rupture/tamponade
|
|
systolic mitral regurg murmur, peristent st elevations one month later post mi, dx
|
left ventricle aneurysm
|
|
canon a waves indicate
|
atria and ventricle no synchronized
|
|
canon a waves can be due to
|
3rd degree heart block
v fib |
|
ten weeks post mi, low grade fever, pleuritic chest pain dx
|
dresslers
|
|
young person, develops chf picture dx
|
mycocaditis, prolly coxasckie
|
|
how to tell the difference between chf and primary pulmonary htn
|
pulmonary capillary wedge pressure
pulmonary htn: normal pcwp chf: increased pcwp |
|
pleural effusion, transudative, low glucose
|
rheumatoid arthritis
|
|
pleural effusion, transudative, high lymphocytes
|
tb
|
|
pleural effusion, transudative, bloody
|
pe or cancer (cancer can be transudative sometimes)
|
|
how to define complicated pleural effusion
|
grams stain postive or culture positive
PH less than 7.2 glucose less than 60 |
|
how to determine if pleural effusion is transudative or exudative
|
Lungs/serum
PRotein .5 LDH .6 LDH <2/3 of normal serum: transudative |
|
copd patient comes in with new onsent clubbing, next step and probable dx
|
chest x ray looking for cancer
dx: hypertrophic osteoarthropathy |
|
nodule in upper lobe with egg shell calcifications
|
silicosis
|
|
reticulonodular plaques in lower lobes
|
asbetosis
|
|
important referral in pt with sarcoid
|
optho
|
|
hearing loss, increased hat size
|
pagets
|
|
what antibody is positive in autoimmune hepatitis
|
anti smooth muscle
|
|
who gets chemoprophylaxis in known tb exposure
|
kids less than 4
|
|
strep bovis bacteremia next step
|
colonoscopy
|
|
hiv pt, seizure, rbc's in lp, aura next step
|
start acyclovir for HSV
|
|
hiv, person starts developing focal neuro signs mimicking MS, best dx step
|
biopsy for PML
|
|
Absolute neutrophil count less than 500 and fever, dx
|
neutropenic fever
|
|
most common cause of fever in neutropenic
|
mucositis from NORMAL gi flora
|
|
most common bugs in neutropenic fever
|
pseudomonas
staph |
|
what is first line tx for neutropenic fever
|
3rd gen cephalo
|
|
what drug is added to empiric tx for neutropenic fever if there is a port present
|
vanco for staph coverage
|
|
if neutropenic fever pt doesnt not improve within 5 days of empiric therapy, what is next step
|
amphotericin for suspected fungal cause
|
|
metabolic alkalosis with increased urine chloride >20, hypertensive
|
conn syndrome
|
|
metabolic alkalosis with increased urine chloride >20, normotensive
|
barter/gittleman
|
|
metabolic alkalosis with decreased urine chloride <20
|
vomiting
ng suction |
|
most common cause of the rta
|
type one: lithium
two: myeloma four: diabetes |
|
treatment for the rta
|
one: oral bicarb and potassium
two: thiazide and k four: fludrocortisone |
|
enveloped shaped crystals on ua
|
ethylene glycol
|
|
what type of stone with alkaline pee
|
struvite (mg po4 ammonia)
|
|
family hx of stones, what type
|
cysteine (cannot abs cysteine)
|
|
nephrotic pt with flank pain dx
|
renal vein thrombosis
|
|
mcc nephrotic in adult
|
membranous
|
|
nephrotic plus iv drug use
|
fsgs
|
|
neprhotic, chronic hepatitis, low complement
|
membrano proliferative
|
|
first clotting factor depleted in liver failure
|
7
therefore what test will increase first pt |
|
initial step in multifocal atrial tacy workup
|
o2 stats
|
|
first test to order in pt with suspected acromelgaly
|
somatomedin c aka igf one
|
|
pt presents with cholelithiasis but only abnomality found is dilated bile duct, next step and likley dx
|
ercp
sphincter of oddi dysfunction |
|
pt has itp, no evidence of bleeding, when to start steroids
|
less than 30,000
|
|
how to treat hyper PO4
|
oral calcium acetate and carbonate
|
|
birbeck granules pathomneumonic for
|
eosoinophlic granulomatosis also called histiocytosis x
|
|
arthritis plus nail pitting or nail changes
|
psoriatic arthritis
|
|
next step when aortic stenosis is found
|
echo
|
|
first line tx for hepatic encephalopathy
|
lactulose
|
|
zoster tx
|
anti viral plus desipramine (tca)
|
|
severe allergic rhinitis that doesnt respond to antihistamines
|
ten day of steroid
|
|
what murmur is present in aortic dissection
|
aortic regurg
|
|
treatment of wegners
|
STEROIDS AND CYCLOPHOSPHAMIDE
|
|
treatment of CAP in comorbid patients
|
ceftriaxone and azythro
or amox/clax or quinolone |
|
what are the risks for squamous cell Ca in esophagus other than smoking and alcohol
|
lye ingestion
achalasia |
|
what is TLC and DLco in asthma
|
TLC: increased
DLco: normal |
|
next step if positive stress test
|
angio/cath
|
|
what is tx for hepatorenal
|
transplant
|
|
pigmented macrophages in colon on colonoscopy
|
chronic laxative use: melanosis coli
|
|
drug that is most effective at reducing mortality in MI
|
aspirin
|
|
what valve abnormailty is associte with coart
|
aortic stenois (bicuspid aortic)
|
|
otherwise healthy immigrant with new onset seizure next step
|
head ct for neurocystercosis
|
|
person is taking EPO for CKD, hb/hct increases, then starts to decrease, next step
|
stop epo
transfuse treat underlying cause (eg infection) |
|
treatment of 2nd degree av block
|
PACEMAKER
|
|
treatment of 3rd degree av block
|
PACEMAKER
|
|
axr doesnt show stone, but ct does, what type of stone and treatment
|
uric acid,
oral hydration, pain killers, potassium citrate |
|
air in renal parenchyma,
dx, what is organism, and who is susceptible |
emphesematous pyelonephritis
e coli diabetics |
|
person has super therapeutic INR and has cranial bleed, next step
|
transfuse FFP
|
|
asthmatic with pulsus paradoxicus, next step
|
intubation
|
|
CD8 and diffuse
|
poly
|
|
autoantibodies and perifascilar
|
dermato
|
|
treatment of iga nephropathy
|
ace inhibitors
|
|
in patient with diabetes what is goal cholesterol
|
<one hundred
|
|
treatment of fibromyalgia
|
first: tricyclics
next: nsaid plus: exercise |
|
next step in blood in stool in pts less than 45, greater than 45
|
<45: anoscopy and sigmoidoscopy
>45: colonoscopy |
|
person has raynauds and positive nail fold microscopy, what are the at risk for
|
mixed connective tissue disease
|
|
varicies in mid esophagus and facial edema
|
svc syndrome
|
|
varicies in distal esophagus and stomach
|
portal htn
|
|
what bug and what is the tx of peritoneal dialsysis infection
|
staph
keflex and ceftazidime |
|
is malaria in brazil resistant or non
|
resistant
|
|
what is the tx of strep pneumo meningitis in order
|
first: dexamthasone
next: vanco next: ceftriaxone |
|
gram negative rod, looks like safety pin, bipolar wright stain
|
yersinia pestis
|
|
thickening of stomach folds, hypoproteinemia
|
menetriers disease
|
|
brain mass with tail
|
meningioma
|
|
huge dilation of intrahepatic dcuts
|
caroli disease
|
|
difference between lepromatous and tuberculoid leprosy
|
lepromatous: good immune function, will have granulomas and postive AFB
tb: no granuloma, poor immune |
|
what electrolyte is deficient in alcholics and what other deficiency will it cause
|
Mg, will cause hypoCa due to it being needed for PTH
|
|
how to tell the difference between PCP and strep pnuemo in aids
|
PCP: interstitial pneumonia, chronic, cough for a while, no f/c/s
strep pneumo: lobar pneumonia, acute, much sicker, f/c/s |
|
pseudohyphal mycelia and budding yeast dx
|
candida
|
|
person has recurrent candida infections, what do yuo have to rule out
|
DM first, then HIV
|
|
palpable mass in abd, flank pain,, hematuria dx
|
renal cell carcinoma
|
|
HTN, flank pain, hematuria dx
|
PCKD
|
|
multiple skin cancers in sun exposed area
|
xeroderma pigmentosa
|
|
tx for pericarditis
|
nsaid
|
|
fever, bone pain, effusion, conjunctival hemorrahge dx
|
dengue
|
|
next step in a person with barrets and has
no dysplasia low grade high |
no dysplasia: enod every 3 years
low: 6-twelve months high: surgery |
|
bleomycin side effect
|
pulmonary fibrosis
|
|
busulfan side effect
|
pulmonary fibrosis
|
|
vincristine/vinblastine side effect
|
peripheral neuropathy
|
|
cyclophosphamide side effect
|
hemorragic cystitis
|
|
cisplatin side effects
|
deafness
renal failure |
|
what do you have to check before starting doxo
|
ejection fraction
|
|
anti histone antibodies
|
drug induced lupus
|
|
anti jo antibodies
|
dermatomyositis
|
|
initial management of anemia of chronic disease
|
treat underlying cause
|
|
acd is initially treated but fails to improve what is next step and goal Hb
|
EPO
twelve |
|
treatment of CAP that needs hospitlaization
|
quinolone: levo or moxi
doxy ceftriaxone plus azythromycin |
|
Rugae of stomach are hypertrophied and look like brain gyri
|
menetriers disease
|
|
|
sideroblastic anemia
|
|
|
hereditary spherocytosis
|
|
|
burr cells
pk deficiency |
|
|
heinz bodies, bite cells,
g6pd |
|
|
sickle cell
|
|
|
basophilic stippling in lead
|
|
|
auer rod in PML/AML
|
|
|
smudge cell in CLL
|
|
|
reed sternburg cell in hodgkin lymphoma
|
|
microcytic anemia, increased iron, increased ferritin
|
sideroblastic anemia
|
|
6 month old with growth failure, hepatospleno, bony deformities
|
B major thalessemia
|
|
1. Hemolytic anemia
2. Pancytopenia 3. Venous thrombosis |
pnh
|
|
what is osteitis derformans also called
|
pagets disease
|
|
how to tell the difference between osteopenia, osteoporosis, and osteomalacia
|
osteoporosis: decreased bone matrix and mineralization,
Lab values in osteoporosis: normal osteomalacia: normal bone matrix, decreased mineralization, lab values in osteomalacia: abnormal |
|
most common cancer to affect non smoker
|
ADENO
|
|
normal calcium, decreased phosphate, normal PTH, increased alk phos, normal ggt, dx
|
hypophosphatemic rickets
|
|
bradycardia alternating tacy, with a fib or a flutter
dx and tx |
sick sinus syndrome
ventricular pacemaker |
|
resting ekg shows st depressions, next step
|
stress echo NOT excercise
|
|
waht is the first test to do if suspecting ZES
|
serum gastrin
|
|
when is a secretin test done
|
to differentiate between gastrin secreting conditions
- secretin should suppress gastrin normally, in ZES it does not lower the level |
|
tx of papillary muscle rupture after mi
|
emergency surgery
|
|
best initial test in acs workup in person with previous MI or LBBB
|
echo
|
|
fever, stridor, unwillingness to move neck, trouble swalloing, drooling, next dx step and dx
|
lateral neck xr
retropharyngeal abcess |
|
iv drug user, enlarged kidneys, nephrotic
|
amyloid kidney
|
|
rash, conjunctival hemorrhage, watery diarrhea, muscle aches, fever, dx
|
toxic shock syndrome
|
|
how do ocp's affect endometrial and ovarian cancer risk
|
decrease both
|
|
tx of acute gout attack in renal insuficinecy
|
steroids
- have to avoid using indomethiacin or colchicine |
|
which anti tb drug causes anemia, what type andhow
|
isonizaid
causes B6 deficiency leading to sideroblastic anemia |
|
if person has hypothyroid and macrocytic anemia, what do you have to think of as the cause of anemia
|
autoimmune - has a high association with hashimotos hypothyroid
|
|
what is the tx of paget
|
bisphosphonates
|
|
workup of thyroid nodules
|
first step: TSH
if TSH low: do scintiography if tsh normal or high: FNA |
|
best thing to reduce breast cancer risk
|
tamoxifen therapy
|
|
what is the inheritance of G6PD
|
x linked recessive
|
|
what is the inheritance of PK deficiency
|
autosomal recessive
|
|
what is sickle cell inheritance
|
autosomal recessive
|
|
what is inhertance of NF one
|
autosomal dominant
|
|
what is inheritance of CF
|
autosomal recessive
|
|
tay sachs and niemann picks inheritance
|
autosomal recessive
|
|
air in wall of gallbladder, crepitus on exam
dx and tx |
emphysematous cholecystitis
cipro, metro and surgery |
|
orange colored tonsils
|
tangiers disease
|
|
mutliple angiokeratomas on lower half of body
|
fabry disease
|
|
grey brown pigmentation of forehead, hands, pretibial region
|
gauchers
|
|
intubation then black stool dx
|
stress gastritis
|
|
retinal pigmentation, osteomas, colonic polyps, skin cysts dx
|
gardeners syndrome (FAP)
|
|
colon cancer, cns cancer dx
|
turcot syndrome
|
|
what is the oral tx of onchomycosis
|
terbinafine
or itraconazole |
|
if suspecting SLE, what is the first initial antibody test to do
|
anti nuclear antibody (ANA)
|
|
cd22 or cd11 positive
|
hairy cell
|
|
first test to order for EBV and best test for EBV
|
heterophile
IgM to VCA |
|
treatment of asymptomatic hereditary spherocytosis
|
folate
|
|
next step in cholecystitis workup if us is non diagnostic
|
hida scan
|
|
positive drop test dx
|
supraspinatus tear
|
|
nstemi, treated with all the appropriate drug, continues to have chest pain, next step
|
cath
|
|
person presents asymptiomatically with elevated lft's, what is dx
|
non alcoholic steatohepatitis
|
|
what is the association iwth non alcoholic steatohepatitis
|
metaboloc syndrome
|
|
what is the response to ristocetin and adp in:
vwf bernarnd soulier glanzman |
vwf
ristocetin: no response ADP: no response bernard soulier ristocetin: none ADP: aggregation glanzman ristocetin: aggregation ADP: none |
|
treatment for perosn with MI due to volume/blood loss
|
transfusion
|
|
treatment of fap once polyps form
|
total proctocolectomy
|
|
tx with specific abx of ascending cholangitis
|
fluids
ceftriaxone and metron elective sphincterotomy 72 hours later |
|
treatment of graves disease versus thryoid adenoma
|
graves: radioactive iodine ablation
thyroid adenoma: beta blocker, ptu or methi then ablation |
|
how to prevent tumor lysis syndrome
|
fluids
allopurinol or rasburicase |
|
best initial test if suspecting RAS
|
duplex
|
|
treatment of asymptomatic aortic stenosis
|
ace or arb
|
|
cardiogenic shock tx
|
inotropes like dobutamine
|
|
increased range of motion in joint, redness, erythema, diabetic dx
|
charcot joint
|
|
new onset ascites in woman, must make you think of what dx
|
ovarian cancer
|
|
pregnant woman develops intense ithcing and increasing bili, next step
|
deliver fetus since the increasing bili is toxic to it
|
|
tingling of butt and butt pain, worsned by sitting down and bicyle ride, no low back pain, dx
|
piriformis syndrome
if there was low abck pain : sciatica |
|
next step in evaluating person with HOCM after trans thoracic echo
|
24 hour holter
|
|
what type of testicular tumor is in an older man with signs of feminization
|
leydig (makes lots of androgens)
|
|
next step if new onset heart failure and chest pain
|
angio
|
|
loud P2 indicates
|
increased pulmonary artery pressure or mitral stenosis
|
|
what are FSH, LH and FSH/LH ratio in premature ovarian failure
|
fsh: increased
LH: increased fsh/lh: >1 |
|
presence of bilirubin in urine indicates what type
|
conjugated (able to be excreted, unconjugated not)
|
|
how to tell the difference between breastfeeding failure jaundice and breast milk jaundice
|
breastfeeing failure: will not be making enough wet diapers
breast milk: will be essentially normal but has jaundice |
|
what are the initial steps in esophageal varicies bleed
|
first: fluids
next: octreotide next: ceftriaxone abx ppx |
|
treatment of basic physiologic profile <4
|
immediate delivery if >26 weeks
|
|
treatment of bartonella
|
azythromycin
|
|
what is the step wise approach for the treatment of ascites
|
first: salt and fluid restriction
next: spironolactone next: furosemide next: tap the ascites |
|
person has circumfrential burn, steps in management
|
first: escarotomy
next: abx if no relief: fasciotomy |
|
mobile cavitary lung lesion with hemoptysis
|
aspergillous
|
|
biggest risk of asymptomatic bacturia in pregnant pt
|
pyelo leading to pre term birth
|
|
baby hasnt moved in two days, no heart sounds on doppler, next step
|
real time ultrasound
|
|
management of preterm labor at:
24-34 weeks |
first: steroids
next: tocolysis to help get to 34 weeks |
|
which one is not covered in a membrane, gastrochesis or omphalocele
|
gasrochesis
|
|
fever, drooling, muffled voice, trouble swallowing, thumb sign on lateral xr
|
epiglottitis
|
|
fever, drooling, muffled voice, trouble swallowing, widened vertebral spacing on lateral xr
|
retropharyngeal abscess
|
|
solitary lytic bone lesion with hypercalcemia in peds pt
|
langerhans histocytosis
|
|
40yo woman, dysmenorrhea, menorrhagia, enlarged symmetrical uterus
|
adenomyosis
|
|
40yo woman, dysmenorrhea, menorrhagia, enlarged asymmetrical uterus
|
leomyoma (fibroid)
|
|
what vaccines should HIV get
|
yearly flu
HBV strep pneumo HAV if men have sex with men normal guidelines for: HPV, tDap, H flu |
|
first line management for idiopathic intracranial hypertension
|
acetozolamine +/- furosemide
|
|
what 2 infections can cause flaccid paralysis
(lmn lesion) |
polio
west nile |
|
most common causes of bacterial meningitis in these age groups:
0-1month 1month -2yr 2-18yr 18-60 60+ |
0-1month: GBS, e coli, listeria
1month -2yr: S pneumo, neisseria 2-18yr: Neisseria, pneumo 18-60: pneumo, neisseria 60+: pneumo:, listeria, neiseria |
|
treatment of meningitis in these age groups:
0-1month 1month -2yr 2-18yr 18-60 60+ |
0-1month: amp/gent, amp/ceftriaxone,
1month -2yr: ceftriaxone (maybe add vanco) 2-18yr: vanco, ceftriaxone, dexa 18-60: vanco, ceftriaxone, dexa 60+: ampicillin, ceftriaxone, dexa TB meningitis: 4 drug regimen |
|
where is lesion if have:
eyes looking toward lesion |
FEF
|
|
where is lesion if have:
eyes look away |
PPRF
|
|
where is lesion if have:
upward gaze paralysis |
superior colliculus
(parinaud syndrome) |
|
where is lesion if have:
poor repetition |
arcuate fasiculus
|
|
where is lesion if have:
dysarthria |
cerebellar vermis
|
|
where is lesion if have:
agraphia and acalculia |
dominant parietal lobe
|
|
what is the ppx for unvaccinated children exposed to Hib
|
rifampin (same as neisseria)
|
|
kid, hypoglycemia, encephalopahty, recent illness, dx
|
reye syndrome
- hypoglycemia due to hepatic dysfunction |
|
suspecting a viral encephalitis, where would you see swelling in the brain
|
thalamus
|
|
dx, encephalitis with:
skin lesions, aura |
HSV
|
|
dx, encephalitis with:
parotid swelling |
mumps
|
|
dx, encephalitis with:
flaccid paralysis and maculopapular rash |
west nile
|
|
what is the managemnt of brain abscess
|
1. abx
2. STEROIDS 3. drainage |
|
young female with migraine with aura, what should she NOT be on
|
oral contraceptives
increases risk of stroke |
|
1. Contralateral lower limb hemiparesis
2. Contralateral loss of proprioception 3. Ipsilateral tongue deviation dx |
medial medullary syndrome
|
|
what is medial medullary syndrome due to
what tracts are involved in what tracts are spared |
anterior spinal artery occlusion
- LATERAL corticospinal (so lower limbs) - Medial lemniscus carrying dorsal column - Hypoglossal nerve areas spared: spinothalamic |
|
what is lateral wallenburg due to
what area is involved what deficits |
- PICA occlusion from vertebral
- lateral medulla - hoarsness/dysphagia (nucleous ambiguous) - vomiting vertigo - horners - loss of P&T to face |
|
what is lateral pontine syndrome due to
what area is involved what deficits |
occlusion of AICA
- lateral pons - FACIAL paralysis, decreased tearing (CN7 nucleus) - hearing loss (CN8) - horners - n/v/vertigo |
|
facial weakness, dyarthria, dysphagia, weakness of one hand dx
|
dysarthria clumsy hand syndrome
- type of lacunar stroke |
|
one sided full body weakness, combination of cranial nerve deficits dx
|
basilar artery stroke
|
|
what type of brain bleed gets seizure ppx
|
parenchymal bleeds
|
|
what 2 diseases most commonly cause NPH
|
sub arachnoid
chronic meningitis |
|
increased afp on quad screen, think of what 2 defects and what 2 conditions
|
most common: inaccurate age
defects: neural tube omphalocele/gastrochisis could also be: multiple gestations |
|
decreased afp on quad screen
|
down syndrome and turner
|
|
the Rb gene mutation predisposes you to what two conditions
|
retinoblastoma
osteosarcoma |
|
indications for cea
|
symptomatic >60%
asymtomatic >80% |
|
biconvex lens hematoma
|
epidural
|
|
crescent shaped hematoma
|
subdural
|
|
treatment for tourette
|
first line:
risperidone guanfacine/clonidine best overall: haloperidol pimozide |
|
what are the three most common causes of neonatal respiratory distress and what are they due to
|
transient tacypnea of newborn
- all the mucus hasnt been cleared yet neonatal respiratory distress - deficient surfactant persistent pulmonary HTN -persistant shunting through pfo and pda in post term infants |
|
how to tell persistent pulmonary htn, respiratory distress and transient tacypnea from each other
|
CXR
PP HTN: clear lung fields RDS: ground glass opacities TTNB: linear perihilar streaking |
|
first line tx for pin worm
|
albendazole/mebendazole
|
|
bilious vomiting in first days of life ddx
|
biliary atresia
necrotizing enterocolitis |
|
what heart defects are associated with down
|
complete AV canal - most common
vsd asd |
|
what GI defects are associated with down
|
biliary atresia
hirschprungs disease imperforate anus |
|
mcc of asymptomatic vaginal discharge
|
chlamydia
|
|
orthostatic hypotension, impotence, rigidty, tremor, dx
|
shy drager
|
|
painful third semester bleeding dx
|
abrupto placenta
|
|
non painful third trimester bleeding
|
placenta previa
|
|
symmetrical arthritis involving wrist, mcp, pip, goes away after 20 min, no esr elevation, dx
|
parvovirus arthirtis
|
|
broad/waxy casts dx
|
chronic renal failure
|
|
ppx for cat bites
|
amox/clav
|
|
sudden loss of vision and floaters
|
vitreous hemorrhage
|
|
what causes the physiologic changes associated with pregnancy
|
progesterone
|
|
HIV pt, painless vision loss, fluffy granular lesions around vessels
|
CMV
|
|
HIV, painful vision loss, keratitis
|
HSV
|
|
first line tx for endometritis
|
clindamycin and gent
|
|
what are the three most common cdv anomalies in turner
|
biscupid aortic (most common)
coarct (#2) aortic root dilation (#3) |
|
how to tel the difference between legg calves perthes and SCFE
|
legg: kids <10 and chronic pain
SCFE: fat teens, >10 and insiduous pain |
|
what arrythmia does dig cause
|
Atrial tacy with AV block
|
|
next test if elevated AFP
|
us
|
|
when is amniocentesis done
|
after 16 weeks
abnormal quad screen women >35 |
|
when can cvs be done
|
earlier than amnio
10-12 weeks -has greater risk than amnio |
|
Normal breast, absent uterus/blind vagina, normal ovaries, normal axillary hair
|
mullerian agenesis
normal breast = estrogen present normal axillary hair = androgens present ovaries present: NOT a mullerian structure |
|
Normal breast, absent uterus/blind vagina, no axillary/pubic hair, dx and complication
|
dx: androgen insensitivity
complication: testicular cancer |
|
ddx of early post partum bleeding and how to tell apart
|
1. Uterine atony – boggy uterus seen
2. Genital tract laceration - firm uterus yet bleeding 3. Uterine inversion – something sticking out of cervix 4. Placental accrete or retained placenta |
|
what cell type makes surfactant
|
type 2 pneumocytes
|
|
when is quad screen done
|
16-18 weeks
|
|
when is gbs screened for
|
36 weeks
|
|
increased nuchal translucency what 3 things
|
down
turner hear defect |
|
when does surfactant production begin
|
24 weeks
|
|
how does bp change in pregnancy
|
decreases in first 2 trimesters, normalizes in third
- therefore any HTN is abnormal |
|
how are RV, FRC, and ERV, and minute ventilation changed in pregnancy
|
RV: decreased
FRC: decreased ERV: decreased (all due to diaphram being pushed up) minute vent: increased (due to increased TIDAL volume, not RR) |
|
how much weight should a woman gain in pregnacy if bmi:
<20 25-35 >35 |
<20: 35lbs
25-35: 25lbs >35: 15lbs |
|
increased inhibin A
|
down syndrome or turner
|
|
how to tell tri 21 from tri 18
|
hcg
21: increased 18: decreased |
|
what other condition will have the same quad screen values as down
|
turner
|
|
what cardiac defect is seen in diabetic moms
|
transpostion of great vessels
|
|
epileptic woman gets pregnant, what to do with meds
|
keep same anticonvulsants
-give folic acid and vitamin K in last trimester |
|
first line tx for hyperemesis gravidarum
|
B6 pyridoxine
doxalamine |
|
how is normal n/v in pregnancy distinguished from hyperemesis
|
weight loss >5%
ketones in urine |
|
how are migraines treated in pregnancy
|
opioids
cant use any of the first line stuff |
|
ace/arb teratogen effect
|
oligohydramnios
pulmonary hypoplasia due to: renal agenesis |
|
aminoglycoside teratogen
|
hearing loss
|
|
CBZ teratogen
|
FINGERNAIL hypoplasia
neural tube facial abnormalities |
|
Diazepam teratogoen
|
cleft palate
|
|
DES teratogen
|
clear cell adeno in vagina and cervix
|
|
retinoids teratogen
|
hydrocephalus
CNS defect microtia ==> underdeveloped ear |
|
thalidomide teratogen
|
limb shortening
|
|
sulfa drugs teratogen
|
kernicterus/bile issues
|
|
valproate
|
neural tube
HYPOSPADIA |
|
warfarin
|
Abortion
LIMB HYPOPLASIA |
|
hydrocephalous, intracranial calcifications, chorioretinitis in newborn dx
|
toxo
|
|
hepatospleno, hemolytic anemia, jaundice, blood tinged nasal secretions in newborn dx
|
syphilis
|
|
deafness, cataracts, cardiac malformations, blueberry muffin rash in newborn
|
rubella
|
|
what cardiac abnormalities will be seen in rubella
|
PDA
pulmonary artery stenosis |
|
unilateral hearing loss, microcephaly, intracranial calcifications, chorioretintis in newborn
|
CMV
|
|
conjunctivitis in newborn:
<24hours 2-5 days >5 days |
<24 hrs; chemical from silver nitrate
2-5 days: gonococcal >5 days: chlamydia |
|
encephalitis, pneumonia, choroioretinitis, scarring on skin in newborn, dx and tx
|
VZV
VZV immune globin scarrring will be in dermatomal pattern |
|
hydrops fetalis cause
|
parvo b19
|
|
what indications are for gbs ppx
|
- if gbs is detected at 36 weeks
- gbs bacturia - hx of gbs in previous birth - prolonged rupture of membrane |
|
all pregnant women should be screened for what infections
|
HIV
HBV syphilis |
|
blunting of calyces and scarring on IVP dx
|
chronic pyelo
|
|
how to treat anorexia and cachexia due to cancer
|
progesterone analogs like:
medroxyprogesterone megestrol acetate |
|
elevation of alk phos in elderly and no symptoms, dx
|
pagets
|
|
decreased FEV/FVC ratio, normal DLCO
what 2 conditions |
chronic bronchitis
asthma |
|
big round cyst with daughter cyst
who is at risk and dx |
sheep farmers
echinococcus |
|
anterior shoulder dislocations can damage what nerve
|
axillary
|
|
one sided sensory loss with increased pain to touch, where was stroke
|
thalamus
|
|
strongest risk factor for stroke
|
HTN
|
|
what is the only contraindication to rotavirus vaccine
|
prior hx of intussception
|
|
us of kid shows abdominal circumference <10% for gestational age dx
|
iugr
|
|
most common causes of symmetric and asymmetric iugr
|
symmetric: congenital infection, chromosomal
assymmetric: poor maternal health (more common than symmetric) |
|
what is oligohydramnios associated with in
first second third trimester |
first: spontaneous abortion
appears in second: renal abnormalities appears in third: premature rupture of membranes |
|
treatment of polyhydramnios
<32 weeks >32 weeks |
<32 weeks: indomethiacin + amnioreduction
>32 weeks: amnioreduction |
|
treatment of premature rupture of membranes:
<32 weeks |
<32:
- steroids - tocolysis for 48 hours - Penicillin ABX ppx |
|
treatment of premature rupture of membranes:
32-34 weeks |
depends on fetal lung maturity
- check amniotic fluid - give steroids - tocolysis - ABX ppx if mature: - induce labor - ABX ppx |
|
how is fetal lung maturity determined
|
either
- L:S ratio >2 - presence of PG |
|
treatment of premature rupture of membranes:
>34 weeks |
- induce labor
- abx ppx |
|
what are the signs of mag tox
|
first: loss of DTR
next: resp failure/pulmonary effusion last: cardiac failure |
|
what is the surveillance for multiple gestations
|
- weekly f/u starting at 24 weeks
- weekly non stress tests at 36 |
|
what is considered a reactive fetal stress test
|
2 or more 15bpm accels for at least 15 sec
|
|
whqt are the steps in a non reassuring fetal HR
|
1. O2, turn off pitocin, left lateral decubitus
2. give terbutaline 3. correct maternal hypotension (epidural commonly causes) 4. Vaginal exam 5. Fetal scalp electrode |
|
dx, due to, tx
|
dx: early decel
due to: head compressrion tx: none |
|
dx, due to, tx
|
dx: late decel
due to: uteroplacental insufficiency, hypoxia tx: prompt delivery |
|
dx, due to, tx
|
dx: variable decel
due to: cord compression tx: change mothers position |
|
sinusoidal fetal heart rhythm due to
|
anemia
|
|
definition and time to complete:
stage 1, latent phase |
def: start of contractions to 4cm
time to complete: nulli: 20 hours mutli: 14 hours |
|
definition and time to complete:
stage 1, active |
def: 4-10cm
>12 hours nulli: 1.2/hour dilation multi: 1.5/hour dilation |
|
definition and time to complete:
stage 2 |
def: 10cm to delivery
nulli: <2 or 3 with epi multi: <1 or 2 with epi |
|
definition and time to complete:
stage 3 |
def: delivery until passage f placenta
time: 30 minutes |
|
what is arrest of descent
|
prolonged stage 2
|
|
treatment of uterine hyperstimulation
|
terbutaline to slow conractions
|
|
when are cephalic maneuvers offered for breech presenation
|
36 weeks
|
|
what is the most common type of breech presentation
|
Frank: feet to face
|
|
what is the definition of post partum bleeding
|
vaginal: >500ml
c section: >1 liter |
|
treatment of post partum bleeding
|
first: uterine massage
next: oxytocin if not stopped: methergine or prostaglandin if all else fails: embolization/ligation/hysterectomy |
|
when to supect endometritis
|
fever post partum
uterine tenderness foul smelling lochia leukocytosis |
|
when can ocp's be started up after bitth
|
6 weeks due to dvt risk
|
|
hypoxia, shock, dic, immediately post partum dx
|
AMNIOTIC FLUID EMBOLI
|
|
what types of hyaditform moles exist and what are their genotypes
|
complete: 46
incomplete: 69 |
|
how to tell complete and incomplete moles apart
|
HCG: much higher in complete
fetal parts: found in incomplete preeclampsia, hyperemesis, or hyperthyroidism: complete |
|
when to suspected molar pregnancy
|
- pre ecclampsia in first half of pregnancy
- hyperemeis gravid - hyperthyroid - B HCG higher than expected for age |
|
when to suspect choriocarcinoma
|
- post partum bleeding past 6 weeks
- HCG levels do not do down or increases after delivery |
|
grape like vesicles coming from vagina dx
|
molar pregnancy
|
|
workup of single pulmonary nodule in :
low intermediate high risk |
low: serial ct
intermediate: <1 cm: serial ct intermediate: >1 cm: PET scan then broch high: resection |
|
how to tell the type of murmur in down sydrome
|
AV canal: systolic regurg with loud S2
ASD: fixed split S2 VSD: holosystolic |
|
young woman, pain with climbing or going down stairs dx
|
patello femoral
|
|
treatment of pericarditis in renal failure
|
dialysis
|
|
kid with absent thymic shadow, tons of weird infections, dx
|
scid
|
|
when should birth weight double
|
4 month
|
|
when should birth weight triple
|
12 mo
|
|
when should birth weight quadruple
|
24mo
|
|
abnormal growth from birth should suggest
|
prenatal cause
|
|
normal weight at birth then starts to decline should suggest
|
post natal cause
|
|
consistently low normal growth suggests
|
genetic short stature
|
|
when is first dose of HBV given
|
right after birth
|
|
when does toilet training begin
|
2-3 yr
|
|
when can infant start eating solid food
|
4-6mo
|
|
when can infant drink whole milk
|
1 year
|
|
how may DTaP vaccines in total by 6yo
|
5
|
|
how many HiB by 18mo
|
4
|
|
when can a child tie shoe laces
|
5
|
|
next step if single umbilical artery
|
renal ultrasound
|
|
difference between caput succedaneum and cephalohematoma
|
caput cross sutures
|
|
next step if newborn female has bloody or white vaginal dishcharge
|
nonthing, normal
|
|
spider webbbing or marbling of newborn skin,
dx and tx |
dx: cutis marmorata
tx: none |
|
yellow pustules with red base with eosinophils on it on newborn
dx and tx |
erythema toxicum
leave alone |
|
intense reddening on gravity dependent side, blanching on opposite in newborn
dx and tx |
harlequin color change
leave alone |
|
bluish discoloration over buttoks and base of spine in newborn
dx and tx |
mongolian spot
DOCUMENT IT |
|
how to tell neonatal acne from infantile acne
|
neonatal - occurs around 3 weeks
infantile - 3 months |
|
superficial pustules overlying hyperpigmented macules in newborn
|
transient neontal pustular melanosis
|
|
when is a child most at risk for sids
|
2-4 months
|
|
what to suspect when anterior fontanelle isnt closed by 2 years
|
1. down
2. achondroplasia 3. rickets 4. hypothyroid 5. increased ICP |
|
soft occipital bone like ping pong ball classic for
|
rickets
|
|
white gray spots with red base on buccal mucosa, rash that starts on behind ears and spreads dx
|
rubeola measles
|
|
lymphadenopathy then rash that starts on face and spreads
|
rubella german measles
|
|
oral vesicles on mouth and tongue, with rash
|
coxsackie
|
|
ddx for desquamating of hands and feet
|
1. scarlet fever
2. kawasaki 3. TSS |
|
high fever, kid is acting normal, bulging anterior fontanella, then develops rash
|
roseola HHV6
|
|
fever and mouth ulcers that keep reappearing every month dx
|
periodic fever apthous ulcer pharyngitis and adenitis
|
|
what kids need a workup for UTI
|
any boy
girls <3 febrile UTI |
|
what is the workup for a child with UTI
|
VCUG
renal US |
|
respiratory quotient >1 means
|
excess carbs in diet
|
|
fever, severe, morning headaches, focal neuro signs dx
|
brain abscess
|
|
should dystocia with clavicle irregularity
|
fractured clavicle
|
|
shoulder dystocia with crepitus over upper arm and irregularity
|
humerus fracture
|
|
shoulder dystocia with ptosis and miosis
|
klumpke palsy
c8, t1 |
|
shoulder dystocia, intact grasp reflex, decreased bicep and moro
|
erb duchenne palsy
|
|
battery is found in kids:
esophagus distal to esophagus |
e: endoscopic removal
distal: wait for it to pass and f/u with xr |
|
hammer toes, ataxia, dysarthia, frequent falls, scoliosis
|
friedrichs ataxia
|
|
what are the leading causes of death in friedrichs ataxia
|
hypertrophic cardiomyopathy
respiratory complications |
|
the more precise a study is the ____ the confidence interval
|
smaller
|
|
"dimorphic" (2 sizes of RBC on smear), normal iron studies, dx
|
sideroblastic anermia
|
|
mosaic pattern of lamellar bone
|
paget
|
|
what is the cause of the edema in a person with bilateral wheezes, jvd, no pulmonary edema, peripheral edema, ascites
|
pulmonary artery HTN
|
|
recurrent otitis media, pneumonia, diarrhea, no viral or fungal infections, no B cells on peripheral smear, dx
|
Brutons Agamma globulinemia
|
|
no thymic shadow ddx
|
digeorge
scid |
|
kid with daily fevers, rash, arthritis, anemia, leukocytosis dx
|
JRA or ALL
|
|
if a child has a TE fistula what else do you have to look for
|
VATER
Vertebral Abnormalities Anal Imperforation TE Fistula Renal Anomalies |
|
treatment of kawasaki disease
|
aspirin
IVIG |
|
male with features of turner syndrome
|
noonan syndrome
|
|
situs inversus, chronic sinusitis, otitis media
|
kartagener syndrome
|
|
painless rectal bleeding in early childhood, how to dx
|
meckel
technetium scan |
|
infant between 4-10 months with colicky abd pain, normal behavior when pain goes away
|
intussception
|
|
bloody diarrhea + cns features
|
shigella
|
|
poor smooth pursuit of target with eyes, ataxia, rash on face, increased AFP
|
Ataxia telangiectasia
|
|
NBT test stays yellow dx
|
chronic granulomatous disease
|
|
albinism, recurrent skin infections, recurrent respiratory infections, giant cytoplasmic granules in MNs
|
chediak higashi disease
|
|
delayed separation of umbilicus
|
leukocyte adhesion deficiency
|
|
young kid with recurrent infections, doughy skin, two sets of teeth
|
Jobs Hyper Ig E syndrome
|
|
hypopigmented macules on woods lamps, leathery skin thickening, at risk for what tumors
|
rhabdomyomas
brain hamartomas renal angiolipomas |
|
lactic acidosis, hepatosplenomegaly, severe fasting hypoglycemia, increased glycogen in liver dx
|
von gierke
|
|
cardiomegaly, diaphragm weakness on young kid
|
pompe
|
|
hepatomegaly, hypoglycemia, normal lactate in kid
|
cori
|
|
painful muscle cramps in young kid with excercise
|
mcardles
|
|
vitamin or mineral deficiency:
increased RBC fragility |
vit E
|
|
vitamin or mineral deficiency:
dermatitis, glossitis, cheilosis |
iron
or B vitamins |
|
dermatitis, diarrhea, dementia
|
Niacin B3
|
|
headache and extraocular muscle palsies
|
cavernous sinus thrombosis
|
|
drug that causes gingival hyperplasia as side effect
|
phenytoin
|
|
what type of seizure has hallucinations, deja vu, and post ictal confusion
|
complex partial
|
|
what type of seizure has spike and wave pattern on eeg
|
abscence
|
|
treatment of serotonin syndrome
|
1. stop drug
2. supportive 3. cyproheptadine |
|
treatment of TCA overdose
|
sodium bicarb
|
|
what are contraindications to buproprion
|
1. seizure
2. alcoholics 3. eating disorders |
|
depression with poor appetite tx
|
mirtazepine
|
|
pt has sexual dysfunction from ssri, what is tx
|
switch to buprioprion
|
|
treatment of nephrogenic DI from lithium
|
thiazide
PLUS amiloride |
|
how are phobias treated
|
CBT
|
|
how to distinguish amphetamine intox from heroin withdraw
|
heroin withdraw: patients appear agitated amphetamine: have psychotic sx
|
|
Anxiety, auditory hallucinations, tremors, n/v withdrawing from what
|
Benzo
|
|
what are the 3 possible pharm tx for nms
|
1. Dantrolene
2. bromocryptine 3. amantadine |
|
Nausea, vomiting, abd pain, muscle and joint aches, pupillary dilation
|
Heroin withdraw
|
|
first degree relatives of bipolar have what % of getting it
|
25
|
|
treatment of atypical depression
|
phenelezine (MAOi)
|
|
what drugs increase lithium levels
|
nsaids
ace thiazides |
|
person is being treated for depression, stops his med then feels depressed 2 days later what drug was he on
|
paroxetine
|
|
What part of the brain is wrong in tourettes
|
Basal ganglia
|
|
what other disorders are these drugs used for:
imipramine desipramine |
imipramine: enuresis
deipramine: OCD |
|
torticolis or clenched jaw after starting new drug
dx and tx |
dx: acute dystonia
tx: 1. Benztropine 2. Diphenhydramine |
|
treatment of parkinsons symptoms after starting drug
|
benztropine
|
|
drug side effect of Feelings of restlessness, pacing, “engine inside me”
dx and tx |
dx: akasthesia
tx: Short term tx: Benzos Long term tx: Propranolol |
|
lip smacking, excess blinking, writhing movements of mouth months after starting new drug
dx and tx |
dx: tardive dyskinesia
tx: Tx: Benzos, beta blockers |
|
Which two antipsychotics are weight neutral:
|
1. Aripiprazole
2. Ziprasodone |
|
which two antipsychotics cause weight gain
|
olanzapine
clozapine |
|
What side effects are seen with clozapine
|
1. Prolonged QT
2. Agranulocytosis 3. Hyper PRL 4. myocarditis 5. seizures 6. most anticholinergic 7. bad metabolic |
|
which anti convulsant causes kidney stones
|
topiramate
|
|
who gets pertussis ppx for fourteen days
|
everyone reguardless of immunization status
|
|
hepatomegaly and inflammation and destruction of medium sized bile ducts
|
PBC
|
|
person with first unprovoked seizure, they will get what
|
imaging
- either CT without or MRI |
|
workup of primary amenorrhea
|
Pelvic US
- If no uterus: Karyotype and Testosterone - If uterus: FSH FSH high: Karyotype FSH low: pituitary MRI |
|
throat infection, given amoxicillin/penicillin then develops rash
|
EBV
|
|
von gierkes deficient in what
|
g6p enzyme
|
|
pt has spleen removed, what to give afterwards
|
vaccinations
daily penicillin ppx for 5 yrs after |
|
child who still has persistent ear discharge weeks after being treated
|
cholesteatoma
|
|
treatment of symptomatic and asymptomatic sarcoid
|
asymptomatic: should go away on own
symptomatic: steroids |
|
prior to what year to pts need to be screened for both hbv and hcv if they received a blood transfusion,
only hcv? |
86
92 |
|
sickler with drop in Hb, but no rise in retic count, dx and tx
|
aplastic crisis
tx: transfusions |
|
how is aplastic crisis different from aplastic anemia
|
aplastic crisis: only hb is down
aplastic anemia: pancytopenia |
|
fever, chest pain, infiltrates on cxr in sickler, dx
|
acute chest syndrome
|
|
what is the bug that causes endocarditis after urinary procedures
|
enterococcus
|
|
what endocrine issues will be associated with depression
|
high cortisol - will not be suppressed by dexa
hypothyroid |
|
treatment of depression with psychotic features
|
antipsychotic
|
|
most common complication of supracondylar fracture
|
brachial artery injury
|
|
how to tell reactive arthritis from gonococcal
|
reactive: has mouth ulcers, eye involvment
gonococcal: rash, fever |
|
ddx of delayed passage of meconium
|
hirchsprungs disease
CF |
|
kid with webbed neck, short stature, cleft lip, shielded chest, macrocytic anemia, no retics being made, normal platelets, normal leukocytes
|
diamond blackfan anemia
- key is only decreased hb, normal plt and leuks |
|
tick bite, leukopenia, thrombocytopenia, elevated liver enzymes dz
|
ehlichiosis
|
|
tick bite, rash, jaundice, dark urine, hemolysis
|
babesia
|
|
person making illegal drugs develops parkinsons, dx
|
MPTP poisoning
|
|
unilateral progressive motor weakness, intact sensation, fasiculations
|
ALS
|
|
what are the C's of HD
|
CAG repeat
Caudate and Putamen Atrophy AcH decrease GABA decrease Choreaoform Crazy |
|
treatment of HD
|
block dopamine with antipsychotics
|
|
central vision loss, loss of eye aduction with nystagmus in other, eye pain
|
MS
dx: - optic neuritis - INO |
|
best test to dx MS
|
MRI
|
|
dx of MG
|
edrophonium tensilon test
postive AcH antibodies |
|
bilateral facial paralysis ddx
|
lyme
GBS |
|
tx for bells palsy
|
glucocorticoids
eye care |
|
symmetric muscle weakness, decreased reflexes, intact sensation dx
|
GBS
|
|
what finding is seen on LP for GBS
|
increased protein, normal WBC
called: albumino cytological dissociation |
|
how to dx GBS
|
EMG
|
|
all pts with MG require what imaging
|
CT chest for thymoma
|
|
most common brain tumors in adults
|
MGM Studios
1. Mets 2. GBM 3. Meningioma 4. Schwannoma |
|
Most common brain tumors in kids
|
Astrocytoma
Medulloblastoma Ependymoma |
|
next step in dx workup if brain cancer found
|
full body scan for other primary malignancy
|
|
treatment of hemiballismus
|
block dopamine: Haloperidol
|
|
obese person, hypersomnolent, polycythemia, facial redness, peripheral edema dx
|
pickwickian syndrome
polycythema and redness from: hypoxemia peripheral edema from: PULMONARY HTN*** |
|
treatment of restless leg syndrome
|
pramipexole
ropinerole |
|
coma large non reactive pupils dx
|
uncal herniation/epidural bleed
|
|
coma small reactive pupils
|
thalamic involvement
|
|
coma pinpoint pupils
|
opioids, excessive cholinergic
|
|
coma, eyes move toward water on caloric
|
intact midbrain
|
|
coma, eyes do not move with caloric
|
CN 7 and 8 gone
|
|
coma eyes nystagmus with caloric
|
person is faking
|
|
coma, decorticate positioning
|
above red nucleus, cortical involvement
|
|
coma, decerebrate
|
beloe red nucleus by midbrain
|
|
lesion of optic chiasm
|
homonymous hemianopsia
|
|
lesion of optic tract
|
bitemporal hemianopsia
|
|
temporal lobe lesion causes what visual defect
|
upper quadrantopia
|
|
optic radiation to lingual gyrus lesion
|
upper quadrantopia
|
|
optic radiation to cuneus lesion
|
lower quadrantopia
|
|
parietal lobe lesion causes what visual field defect
|
lower quadrantopia
|
|
occipital lobe lesion causes what visual field defect
|
homonymous hemianopsia with macular sparing
|
|
pink eye with:
diarrhea or upper respiratory cough |
adenovirus
|
|
what are inflammatory and autoimmune causes of uveitis
|
inlamm: UC and Crohns
AI: JRA, psoriatic, Ankylosing, Reactive arthritis |
|
peripheral vision loss with floaters dx
|
glaucoma
|
|
inflamed hard, dilated, non reactive pupil dx
|
close angle glaucoma
|
|
bilateral central vision loss
|
macular degeneration
|
|
painless loss of vision like a curtain pulled down with floaters
|
retinal detachment
|
|
flame hemorrhages, AV nicking, cotton wool spots dx
|
HTN
|
|
hemorrhages and microaneurysms with yellow exudates on fundoscopy
|
Diabetic
|
|
painful swollen ear with white discharge, red ear canal, normal TM
treatment |
polymyxin or neomycin
|
|
treatment of meniere
|
anticholinergics, anti Histamine
|
|
non tender, unilateral eyelid swelling dx
|
chalazion
|
|
tender, red swellling at eyelid margin
|
hordeolum
|
|
red swollen eyelid margins and dandruff on lashes
|
blepharitis
|
|
- painless progressive decrease in vision
- trouble driving at night - terrible glare from sunlight or headlights dx |
cataracts
|
|
how is orbital cellulitis different from periorbital
|
orbital has:
- bulging eye (proptosis) - limitation of eye movement - painful eye movement - decreased vision |
|
what is the treatment for orbital cellutitis
|
vanco
and cefotaxime |
|
large reddish vesicles on TM dx
|
bullous maryngitis
|
|
what is tx and what causes bullousmaryngitis
|
mycoplasma
macrolid |
|
gray white pearly lesion in ear dx
|
cholesteatoma
|
|
sudden vertigo, nausea vomiting, normal hearing
- symptoms peak at 24hours |
vestibular neuritis
|
|
vertigo, nausea vomiting, decreased hearing
|
labyrinthitis
|
|
brain tumor with calcifications and fried egg in BG or Thalamus
|
oligodendroglioma
|
|
tumor in 4th ventricle, solid
|
medulloblastoma
|
|
tumor in 4th ventricle, solid and cystic
|
pilocytic
|
|
what can be used to treat parkinsons tremor early on in disease
|
anticholinergics
|
|
what is amantidine good for in PD tx
|
increased dopa so helps rigidity, movement
|
|
falls, parkinsons, limitations of upgaze dx
|
PSP
|
|
head trauma, vertigo, tinnitus hearing loss
|
labyrinth concussion
|
|
patient hears "pop" in ear after sneezing, then develops vertigo dx
|
perilymph fistula
|
|
vertigo and fullness of ear sensation
|
meniere
|
|
- bilateral weakness
- Arreflexia - cant move eyes - Ataxic giat |
miller fisher GBS variant
|
|
- Teen with symmetric slow progressive distal muscle atrophy of legs and feet
and has 1. Hammer toes 2. pes cavus |
charcot marie tooth
- Most common inherited polyneuropathy |
|
person with MG starts treatment, then develops trouble breathing, dx and next step
|
Dx: MG crisis
Tx: 1. Stop pyridostigmine 2. Intubate 3. Steroids/IVIG/Plasma exchange |
|
Pupil is normal and reactive to light, but palsy of ocular muscles, dx
|
Diabetes causing vascular issue
|
|
pt cant look up, pupils constrict more to accomodation than light, dx and due to what
|
parinaud
- pineal tumor |
|
what vaccines do alcoholics need
|
pneumococcus
influenza HAV HBV |
|
treatment of intermittent explosive disorder
|
mood stabilizers
- lithium, cbz, valproate |
|
treatment for anorexia
|
food
|
|
delirium + increased BP + papilledema
|
malignant HTN
|
|
delirium + tacy + tremor + thyromegaly
|
thyrotoxicosis
|
|
dementia + tremor + abnormal lfts
|
wilsons
|
|
person cannot remember traumatic event such as getting raped but can remember long term memoeries
|
dissociative amnesia
|
|
person found who cannot remember their identity and found in different location
|
dissociative fugue
|
|
Persistent or recurrent experiences of being detached from ones body
|
depersonalization disorder
|
|
What symptoms indicate dt instead of withdraw
|
1. Autonomic instablility
2. visual hallucinations 3. delirium |
|
1. Fatigue/sleep alot
2. depression 3. constricted pupils 4. vivid dreams |
cocaine withdraw
|
|
treatment of viral myocarditis
|
supportive
inotropes |
|
who is at risk for herpetic whitlow
|
dentist/healthccare worker
|
|
who is at risk for a felon
|
tailors
|
|
2 biggest risks for neonatal respiratory distress
|
prematurity
diabetic mother |
|
treatment of chlamydial conjunctivitis
|
ORAL erythromycin
|
|
ptx despite having chest tube in
|
tracheobronchial rupture
|
|
newborn is intially fine, at about one month develops diarrhea, failure to thrive, thrush, eczema dx
|
hiv
|
|
treatment of kleptomania
|
CBT
|
|
what type of organ failure should metformin not be given
|
kidney
and liver |
|
bilateral deafness newborn what infection
|
rubella
|
|
treatment of actinomycosis
|
penicillin
|
|
treatment of nocardia
|
bactrim
|
|
how to tell drug allergy vs rash from ebv
|
drug allergy: appears minutes after
EBV: 24 hours after |
|
how to distinguish between somogyi effect from dawn effect
|
2am glucose level
|
|
what is the treatment for dawn phenomenon and somogyi effect
|
dawn: increase evening NPH
somogyi effect: 1. decrease evening NPH 2. change NPH to before bed 3. eat snack before bed |
|
best diabetic tx choice in pts with renal failure
|
thiolidazones
|
|
diabetic tx with side effects of pancreatitis
|
exenitide
liraglutide (GLP1 agonists) |
|
treatment of diabetic neuropathy
|
1. gabapentin
2. pregabalin 3. duloxetine |
|
how is diabetic gastroparesis DX
|
gastric emptying studying with barium
|
|
tx of diabetic gastroparesis
|
1. erythromycin
2. metoclopramide 3. cisapride |
|
complications from thyroid surgery
|
1. recurrent laryngeal nerve damage
2. hypocalcemia from PTH damage |
|
when do you perform surgical PTH removal of adenoma
|
if any one of the following:
1. Ca >1 above normal 2. Creatinine decreased >30% 3. Age <50 4. Symptomatic 5. T score <-2.5 |
|
what is the treatment of of hyper PTH due to renal disease
|
1. Hyper PO4: gets protein (PO4) restriction
2. Calcium carbonate to bind PO4 3. Vitamin D analog like calcitriol |
|
first line tx in prolactinoma
|
cabergoline
|
|
what is the first s/s to appear in hyper PRL
|
women: infertility, amenorrhea
men: decreased libido, impotence |
|
steps in tx of GH adenoma
|
first: resection
if cannot be done: octreotide if this doesnt work: cabergoline |
|
next step if person has empty sella syndrome
|
if asymptomatic: reassurance that there is still tissue
sx: replace hormones |
|
what should diabetics do before and during exercise
|
check blood sugar
- turn down pump if they are on one |
|
what pancreatic cells make insulin
|
Beta cells
|
|
how to tell HHS from DKA
|
- no acidosis
- no ketones - only Type 2 diabetics |
|
fever, painful neck mass, increased HR, heat intolerance dx
|
subacute/de quervain thyroiditis
|
|
person gets ct scan, develops, tacycardia, heat intolerance, diarrhea, sweating, anxiety, tremor, dx
|
contrast induced hyperthyroidism
|
|
what drugs can induce hyperthyroid
|
1. amiodarone
2. contrast with iodine |
|
shortneing of 4th and 5th digits
|
albright hereditary osteodystrophy (pseudo hypo PTH)
|
|
what is death due to in acromegaly
|
hypertrophic cardiomyopathy
|
|
how are FSH/LH replaced in hypopituitarism
|
PULSATILE leuoprolide
|
|
treatment of cortisol producing tumor if unresectable
|
1. Ketoconazole
2. metyrapone==> blocks cortisol synthesis |
|
treatment of hyper aldo due to hyperplasia
|
spironolactone
|
|
what is the presentation of 21oh deficiency in:
females males blood pressure K |
females: virilization
males: none bp: hypotensive K: High |
|
what is the presentation of 11oh deficiency in:
females males bp k |
females: virilization
males: none bp: HTN K: low |
|
what is the presentation of 17oh deficiency in
females males bp k |
females: lacks secondary sex characteristics
males: ambiguous genitalia bp: HTN k: low |
|
how to tell secondary adrenal insufficiency from primary
|
skin: no hyperpigment in secondary
K: normal in secondary, high in primary |
|
what diseases are associated with pheos
|
NF1
MEN2A MEN2B |
|
what are the cardiac manifestations of hyperCa
|
1. Hypertension
2. QT shortening |
|
what are the renal manifestations of hyper Ca
|
1. Nephrogenic DI ==>polyuria, polydipsia
2. Kidney stones |
|
If hypercalcemic and PTH level is low, what is the dx
|
malignancy
|
|
what to suspect when a person gets rapidly decreasing ca, mg, phosphate weeks after getting parathyroid removed?
|
Hungry bones syndrome
Due to ==>increased osteoblast activity |
|
Amyloid Deposit in pancreas, which type of DM
|
type 2
|
|
leukcyte infiltrate in pancreas, which type of DM
|
type 1
|
|
what med will not work / should not be given once a T2DM requires insulin
|
sulfonureas
|
|
if suspecting prolactinoma, what is first test to do
|
basal fasting prolactin levels
|
|
Test to diagnose ACTH deficiency
|
metyrapone
|
|
test to dx GH deficiency
|
arginine
or insulin |
|
Fixed, rocklike painless goiter, hoarseness
|
reidels thyroiditis
|
|
fibrous tissue infiltrate found in thryoid, dx
|
reidels thyroiditis
|
|
treatment of thyroid storm
|
First thing to give ==> antithyroid (PTU, methimazole)
Next ==>iodine ==>why ==>inhibits hormone release Next ==>propranolol Next ==>dexamethaxone ==>why ==> inhibits hormone release |
|
Giant cell granulomas on thryoid biopsy
|
de quervains
|
|
pain between third and fourth toes, clicking sound, who is at risk
|
runners
dx: morton neuroma |
|
acute unilateral lymphadenitis in kid can be due to what 2 organsims
|
staph
strep |
|
what do transplant pts receive as abx ppx
|
bactrim
|
|
older woman, vulvar itching, fused labia, likely dx and next step
|
lichen sclerosus
biopsy |
|
woman is found to have ascus, what is next step depending on age
|
<25: repeat pap in one year
>25: HPV tsting |
|
child with fever, conjunctivitis, rash, lip swelling dx
|
kawasaki
|
|
kid with hypopigmented spots, aplastic anemia, bent thumbs, pounding in ears dx
|
fanconi anemia
|
|
hallmark findings of nec on axr
|
intramural air
air in portal veins |