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31 Cards in this Set

  • Front
  • Back
What is the target goal for hyperlipidemic pt with coronary artery disease?
LDL: <100
HDL: > 40
Trig: < 150
What pt are best tx with coronary bypass grafting?
-Left main coronary disease
-three vessel disease
-left ventricular dysfunction
How is STEMI defined?
-persistent ST- segment elevation of > 1 mm in two contiguous limb leads

-ST-segment elevation of > 2 mm in two continguous chest leads

-New LBBB pattern
What are the modifiable risk factors for Ischemic heart disease?
Cholesterol levels
Tobacco
hypertension
physical inactivity
obesity
DM (IHD equivalent)
What are the uncontrollable risk factors for IHD?
-Age:
-Sex
-Heredity
What are some of the symptoms ass. with stable angina?
-substernal pressure lasting 5-15 min
-radiation to jaw, neck, shoulders, arms
-pain mostly after exertion
What are some diagnostic studies in stable angina?
ECG: ST segment depression

Exercise stress test (most useful)

Dobutamine or adenosine stress test

Stress Echo (wall motion abnormalities)
What is the long term tx of stable angina?
-long acting nitrates
-beta blockers
-ASA
-statins
-reduce modifiable risk factors
-evaluate disease w/ stress test and if needed angiography
Thrombolytic therpay can be used in pt with UA and NSTEMI
---FALSO----

They can actually be harmful!!!
What is the definition of unstable angina?
-angina of increasing intensity, frequency, duration
-increase resistance to nitrates
-angina at rest
-new onset angina
What are the ECG readings consistent with NSTEMI?
- ST segment depression
-new T wave inversion (> 2mm)
What is the long term medical management of UA and NSTEMI
- ASA + clopidogrel
- unfractionated heparin (48-72hrs)
-Glycoprotein IIb/IIIa inbitors
-beta blockers
- IV nitroglcerin
What are the invasive management in pt with NSTEMI?
-early coronary angiography (within 48 hrs)

-revascularization
In addition to the symptoms of substernal pain, neck or jaw shoulder or arm pain? What other symptoms are in STEMI?
-Additional symptoms
-dizziness
-nausea
-vomiting
-diaphoresis
-dyspnea

**longer than 20 min***
What pts are ass. with atypical symptoms in STEMI and what are those symptoms?
-women, elderly, diabetics

-symptoms: nausea or dyspnea
Describe the ECG features of STEMI...
- Persistent ST seg elevation of > 1mm in two contiguous limb leads
-ST seg elevation of > 2mm in 2 contiguous leads
-New LBBB pattern
What is the initial management in a pt who presents with possible MI?
N: nitroglycerin
A: ASA
O: Oxygen
M: morphine
I: IV access
Pt with STEMI must present within ___ hrs to be considered fro reperfusion therapy?
12 hrs

*remember NSTEM does not need reperfusion therapy
Which is a better treatment for STEMI PCI or thrombolytics?
PCI (percutaneous coronary intervention)
How long do you have to initiate tx in PCI?
90 min!!
What are the thrombolytics commonly used?
streptokinase
TPA
In which pt can thrombolytic agents be used as an alternative to primary PCI?
in ST elevation MI (>1mm
New LBBB
What pt are need to be considered for cardiac surgery after an STEMI?
- failed PCI with persistent pain
- persistent or recurrent ischemia refactory to medical therapy
What are the recommended discharge meds after ACS?
1. Aspirin (75-325mg)
2. Clopidogrel
3. Beta blackers (metoprolol and carvedilol in HF)
4. ACE inhibitors (those CHF)
5. Statins (everyone)
6. Nitrates
7. Warfarin (only those at risk for thrombus formation)
What drugs have been show in pt with ischmic heart disease to decrease mortality?
-Statins
-ASA
-beta blockers
-Cabg in triple vessel disease
What are the bacteria associated with acute endocarditis?
S. aureus
gram negative
What are the bacteria associated with subacute endocarditis?
Strep viridans
Enterococcus
Staph epidermdis
Strep bovis (ass with GI malignancy)
What pt are considered to be high risk for endocarditis?
ALL prosthetic valves
previous endocarditis
surgical pulmonary stenosis
What is the empirical tx for suspected endocarditis?
Vanc or
ceftraxone + gentimicin
what antibiotic is used for oral dental procedures to cover for endocarditis?
amoxicillin
What is dukes criteria for endocarditis?
Major: + blood cultures, evidence of endocardial involvement

Minor:
risk factors
fever
vascular phenomena
immunological: GN, oslers nodes, roths spots
Microbiological evidence