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3 Cards in this Set

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Trastuzumab (Herceptin)



indication

1st line treatment of metastatic breast cancer with paclitaxel that displays over expression of the human epidermal growth factor receptor 2 (HER2) protein

Trastuzumab (Herceptin)


Action

a monoclonal antibody that binds to HER2 sites in breast cancer tissue & inhibits proliferation of cells that overexpress HER2 protein.

Trastuzumab (Herceptin)


Side effect

interstitial pneumonitis, pulmonary edema, pulmonary fibrosis, arrhythmia, HF, HTN



assess for infusion related symptoms -- chills, N/V, Fever, pain


HF -- dyspnea, PND, peripheral edema


pulmonary hypersensitivity



report SOB, cough, swelling leg, face, palpitation, weight gain