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62 Cards in this Set
- Front
- Back
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decrease: N3, SL, spindles increase: SE no effect: REM |
benzodiazepines |
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decrease: REM, SL increase: REM latency no effect: NREM CNS depression enhanced by alcohol |
TCAs |
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decrease: REM, increase: SL, REM latency, restlessness no effect: NREM insomnia, agitation |
SSRIS (particularly fluoxetine) |
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decrease: REM, SL increase: NREM, SE, restlesness no effect:na |
Antipsychotics |
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Decrease N3 |
Benzodiazepines |
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What four drugs Decrease: SL Increase: SE |
Benzos, Nonbenzos, Antipsychotics, TCAs |
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decrease: NREM, REM increase: sleep fragmentation no effect: na |
opioids |
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What three drugs Increase motor restlessness |
SSRIS, Antipsychotics, Diphenhydramine |
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What two drugs Increase REM Latency |
Antidepressants, Stimulants |
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What 9 drugs Increase sleep efficiency |
Antipsychotics, Benzodiazepines, Tricyclics, nonbenzos, diphenhydramine, melatonin, valerian, Trazodone, Prazosin |
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What four drugs Decrease SL
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Benzodiazepines, Tricyclics, Antipsychotics, Diphenydramine |
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decrease: SL increase: SE, SWS no effect: na |
Trazodone |
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What two drugs Decrease SWS |
SSRIs, Benzos |
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Increase NREM |
Diphenhydramine, Antipsychotics |
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Decrease NREM |
Opioids |
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decrease: SL, SE, R increase: disruption, snoring, apnea no effect: na |
alcohol |
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Increase sleepiness and N3 |
anticonvulsants |
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What antihypertensives most likely disrupt sleep |
beta-blockers (LOL) |
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Alpha adrenergic (methyldopa, clonidine )cause |
sedation |
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Nightmares, drowsiness are reported by patients taking |
antihypertensives |
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Major effect are increased sedation and improved sleep continuity, mild N3 sleep elevation |
antipsychotics |
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REM suppression, sleep disruptions, bizarre dreams |
corticosteroids |
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Increase: W Decrease: TST, N3 W/d causes prolonged periods of sleep and REM rebound |
stimulants |
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Amphetimines/cocaine |
suppress REM |
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Very potent REM suppressors |
Barbituates |
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What antipsychotics are the exception to the effect of increasing N3 |
Quetiapine, Clozapine does NOT increase N3 |
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decrease: N1, Rem latency increase: N3 |
sodium oxybate |
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List 6 drugs that cause Bizarre nightmares/dreams |
Catecholaminergic agents (adrenergic/dopinamergic) Beta blockers Antidepressants Barbituates Alcohol Corticosteroids |
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What anticonvulsant/antiepileptic is the exception to increasing N3 |
Lamotrigine decreases N3 |
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Fatigue, insomnia, nightmares, depression, confusion, psychomotor impairment, decrease melatonin release |
Betablockers |
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Increase: TST, REM, SE Decrease: nightmares |
Prazosin
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Cimetidine (H2 agonist) has adverse effect with |
benzos |
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decrease: N3, REM increase: na no effect: WASO, TST |
opioids |
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Urinary retention is a side effect of what 2 drugs |
histamines and TCAs |
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Other than Xyrem, what 3 drugs treat cataplexy |
protiptyline, desipramine, atomoxetime |
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All TCAs are sedating except |
protryptiline |
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MAOIs and SSRIS most likely to cause |
insomnia |
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Antidepressant that causes insomnia and increase REM |
Bupropion |
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Gabapentin Phenytoin Carbamazepine Valproic Acid |
Antiepileptics/anticonvulsants |
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Amitryptaline, Imipramine Desipramine Protryptiline |
TCAs |
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Paroxetine Fluoxetine Venlafaxine Duloxetine Citalopram Escitalopram |
SSRIs |
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Trazodone Mirtazepine Ramelteon |
MISC antidepressants |
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Temazepam Clonazepam Lorazepam Trizolam |
Benzodiazepines |
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Clozapine Risperidone Haloperidole Quetiapine |
Antipsychotics |
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Levadopa Mehtyldopa Carbidopa |
Antiparkinsonians |
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-LOLs |
Betablockers |
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Lisinopril |
Ace inhibitors |
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amlodipine diltiazem verapamil |
calcium channel blockers |
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What 5 drugs can worsen OSA |
Opiates, Sudafed, Benzos, Nonbenzos, Diphenhydramine |
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What can be used as adjunctive treatment to improve upper airway tone |
SSRIs |
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What are adjunctive treatments for mild osa and snoring |
nasal decongestants, antihistamines |
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Decrease: TST, SE Increase: SL, fragmentation |
NSAIDS |
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Three General side effect of antiparkinsonian drugs are insomnia, nightmares, fatigue |
insomnia, nightmares, fatigue |
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Cimetidine Ranitidine |
H2 agonists |
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H2 agonists have these 3 sideffects |
hallucinations, insomnia, somnolence |
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Broncho dialators have these two side effects |
Sleep onset difficulties, increase awakenings |
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What two drugs can increase R |
Prazosin, Bupropion |
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Name 8 drugs that decrease REM |
Alcohol, Antidepressants, Antipsychotics, Barbituates, Corticosteroids, Diphenhydramine, Opioids, Stimulants, |
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Name 4 drugs that increase SWS |
Trazodone, Anticonvulsants, Antipsychotics, Sodium Oxybate |
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Name 4 drugs that decrease SWS |
Benzos, SSRIS, Stimulants, Opioids |
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What drug decreases REM latency |
Sodium Oxybate |
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WHat drug increases TST |
Prazosin |
