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41 Cards in this Set

  • Front
  • Back
the process by which a drug is transferred from site of entry to the bloodstream
absorption
undesirable effects other than the desired therapeutic effect
adverse drug effect
immune system response that occurs when the body interprets the drug administered as a foreign substance and forms antibodies against the drug
allergic effect
glass flask that contains a single dose of medication for parenteral administration
ampule
allergic reaction resulting in respiratory distress, sudden, severe bronchospasm, and cardiovascular collapse
anaphylactic reaction
life-threatening allergic reaction
anaphylaxis
the combined effect of two or more drugs acting simultaneously producing an effect less than that of each drug alone
antagonist effect
occurs when body cannot metabolize one dose of a drug before another dose is administered (toxicities can occur)
cumulative effect
the disbursement of the drug throughout the body after the drug is in the bloodstream
distribution
becomes accustomed to the effects of a particular drug over time (larger doses are required for the desired effect)
drug tolerance
the process of removing a drug or its metabolites from the body
excretion
identifies the drug’s active ingredient; is often assigned by the original drug manufacturer
generic name
amount of time it takes for 50% of blood concentration of a drug to be eliminated from the body
half life
: any unusual or peculiar response to a drug that may manifest itself by over-response, under-response, or even opposite response
idiosyncratic effect
drugs are aerosolized, delivered in small particles, and breathed in by the patient
inhalation
administered into the dermis, just beneath the epidermis
intradermal injection
delivers medication through the skin and subcutaneous tissues into certain muscles
intramuscular injections
most dangerous route of injection b/c drug is injected directly into the bloodstream and had immediate effect and no absorption time
intravenous route
the change of a drug from its original form to a new form (biotransformation)
metabolism
intended for intermittent infusion; battery operated; allows medicine mixed in a syringe to be connected to the primary IV line and delivered with mechanical pressure to the syringe
mini infusion pump
name by which drug is identified in official publications (USP or NF); is often the generic name
official name
route by which drug is injected into body
parenteral route
highest plasma concentration of the drug (should be measured when absorption is complete)
peak level
the process by which drugs alter cell physiology and affect the body
pharmacodynamics
Synthesis of purine begins with attachment of _____ from ____ to ribose moiety (PRPP)
-amino group
-Gln (glutamine)
requires the intermittent or additive solution to be placed higher than the primary solution container
piggyback
pharmacologically inactive substance
placebo
as-needed order – usually for pain
PRN order
single order carried out immediately
STAT order
administered into the adipose tissue layer just below the dermis and epidermis
subcutaneous injection
the combined effect of two or more drugs acting simultaneously producing an effect greater than that of each drug alone
synergistic effect
developmental effect in the embryo or fetus resulting from a drug
teratogenic effect
concentration of drug in the blood serum that produces the desired effect w/o causing toxicity
therapeutic range
usually intended for direct action to a particular site (some can have, and are intended for, systemic effect)
topical application
specific groups of symptoms related to drug therapy that carry risk for permanent damage or death
toxic effect
name selected by the drug company that sells the drug; protected by trademark
trade name
lowest plasma concentration of the drug (should be measured 30 mins. Before next dose)
trough level
a glass bottle with a self-sealing stopper through which medication is removed
vial
set of drugs diluted with a small amount of water and administered through the patient’s IV line; used when volume of IV fluids is a concern
volume-controlled administration set
skin is moved down or to the side while needle is inserted, drug is injected, needle is withdrawn and tissue moves back into place
z-track technique
effect of the body on the drug-movement of drug molecules throughout the body
pharmacokinetics