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41 Cards in this Set
- Front
- Back
the process by which a drug is transferred from site of entry to the bloodstream
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absorption
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undesirable effects other than the desired therapeutic effect
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adverse drug effect
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immune system response that occurs when the body interprets the drug administered as a foreign substance and forms antibodies against the drug
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allergic effect
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glass flask that contains a single dose of medication for parenteral administration
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ampule
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allergic reaction resulting in respiratory distress, sudden, severe bronchospasm, and cardiovascular collapse
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anaphylactic reaction
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life-threatening allergic reaction
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anaphylaxis
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the combined effect of two or more drugs acting simultaneously producing an effect less than that of each drug alone
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antagonist effect
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occurs when body cannot metabolize one dose of a drug before another dose is administered (toxicities can occur)
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cumulative effect
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the disbursement of the drug throughout the body after the drug is in the bloodstream
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distribution
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becomes accustomed to the effects of a particular drug over time (larger doses are required for the desired effect)
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drug tolerance
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the process of removing a drug or its metabolites from the body
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excretion
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identifies the drug’s active ingredient; is often assigned by the original drug manufacturer
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generic name
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amount of time it takes for 50% of blood concentration of a drug to be eliminated from the body
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half life
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: any unusual or peculiar response to a drug that may manifest itself by over-response, under-response, or even opposite response
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idiosyncratic effect
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drugs are aerosolized, delivered in small particles, and breathed in by the patient
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inhalation
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administered into the dermis, just beneath the epidermis
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intradermal injection
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delivers medication through the skin and subcutaneous tissues into certain muscles
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intramuscular injections
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most dangerous route of injection b/c drug is injected directly into the bloodstream and had immediate effect and no absorption time
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intravenous route
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the change of a drug from its original form to a new form (biotransformation)
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metabolism
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intended for intermittent infusion; battery operated; allows medicine mixed in a syringe to be connected to the primary IV line and delivered with mechanical pressure to the syringe
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mini infusion pump
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name by which drug is identified in official publications (USP or NF); is often the generic name
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official name
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route by which drug is injected into body
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parenteral route
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highest plasma concentration of the drug (should be measured when absorption is complete)
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peak level
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the process by which drugs alter cell physiology and affect the body
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pharmacodynamics
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Synthesis of purine begins with attachment of _____ from ____ to ribose moiety (PRPP)
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-amino group
-Gln (glutamine) |
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requires the intermittent or additive solution to be placed higher than the primary solution container
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piggyback
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pharmacologically inactive substance
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placebo
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as-needed order – usually for pain
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PRN order
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single order carried out immediately
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STAT order
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administered into the adipose tissue layer just below the dermis and epidermis
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subcutaneous injection
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the combined effect of two or more drugs acting simultaneously producing an effect greater than that of each drug alone
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synergistic effect
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developmental effect in the embryo or fetus resulting from a drug
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teratogenic effect
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concentration of drug in the blood serum that produces the desired effect w/o causing toxicity
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therapeutic range
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usually intended for direct action to a particular site (some can have, and are intended for, systemic effect)
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topical application
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specific groups of symptoms related to drug therapy that carry risk for permanent damage or death
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toxic effect
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name selected by the drug company that sells the drug; protected by trademark
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trade name
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lowest plasma concentration of the drug (should be measured 30 mins. Before next dose)
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trough level
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a glass bottle with a self-sealing stopper through which medication is removed
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vial
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set of drugs diluted with a small amount of water and administered through the patient’s IV line; used when volume of IV fluids is a concern
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volume-controlled administration set
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skin is moved down or to the side while needle is inserted, drug is injected, needle is withdrawn and tissue moves back into place
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z-track technique
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effect of the body on the drug-movement of drug molecules throughout the body
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pharmacokinetics
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