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34 Cards in this Set

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LEGISLATION OF CONTROLLED SUBTANCES
HARRISON NARCOTIC ACT- 1914
LAXITIVES WORK
BILE IS NEEDED FOR
ACHOLOHYDRIA
IN COLON
FAT SOULUBLE DRUGS
ABSENSE OF HYDROCLORIC ACID INHIBIT ABSORPTION OF ACID BASED DRUGS
BASIC ALKALINE DRUGS ARE ABSORBED MORE RAPIDLY BY
ALKALINE INTESTINAL MUCOSA
TAKE TETRACYCLINE ON
EMPTY STOMACH
DON'T TAKE WITH MILD
NO CALCIUM
HYALURONIDASE IS AN ANZYME THAT
BREAKS DOWN HYALURONIC ACID IN SQ TISSUE AND ALLOWS QUICKER ABSORBTION
CENTRAL VENOUS LINES - GO INTO WHAT?
SUPERIOR VENA CAVA OR TO RIGHT ATRUM OF HEART- CAUSE THEY ARE DILUTED SO FAST
DRUGS HALF LIFE
TIME NEEDED FOR DRUG TO DECREASE 50%
VECTORS ARE WHAT?
NEEDED FOR DISTRIBUTION OF DNA DURING GENEE THEAPY
LIKE LIPOSOME- BIODEGRADABLE LIPD DROPLETS CARRYING DNA THAT FUSE WITH CELLS
also virus WILL CARRY DNA INTO CELL
WHAT IS FIRST PASS EFFECT?
aCCOUNT FOR THE DIFFERENCE BETWEEN ORAL AND IM ROUTES.
REFERS TO ABSORPTION OF DRUGS THROUGH INTESTINAL TRACT AND THE DRUGS ENTRY INTO THE PORTAL CIRCULATION.
one tablespoon
15 ml
2 tablesppns
30 ml
one tea cup

one cup
180ml

240 ml
1pint
480 ml
milligram =mg
1/1000 of a gram
microgram = mcg or ug
1/1000,000
1 kg =

or 50 k =
2.2lbs

110lbs
1 gram
15 grains
60 mg
1 grain
1 mg 00
1/60 grains
1 g
1000 mg
0.5 grain
500 mg
1 mg
1000 mcg
which is safer
High theraputic index (40)
low theraputic index (20)
high theraputdic index is safer.
when does a drug peak
iv
im
iv: 15-20 minutes
im - one hour later
plateau
it takes four or five half lives for the plama concentraion to reach a steady state or plateau level
electrolyte disturbences
what is the # for
sodium
potassium
sodium 136-135
potassium - 3.5-5.1
chloride
97-107
bicarbonate
24-29
what is Akathisia
motor restlessness
dystonia
acute muscle spasms of face neck face jar tough
tardive dyskinesia
involuntary and abnormal face arm or leg movements
plattletts
150,000 400,000
Thrombocytosis
Overproduction of plattlettes
400,00 +
Thrombocytopenia
Below 100,000