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200 Cards in this Set
- Front
- Back
The endocrine system is composed of ductless glands that secrete...
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chemical messengers, called hormones, into the bloodstream
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endo-
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within
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-crine
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secrete or separate
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target organs |
tissues and organs on which the hormones act
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Hormones may...
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excite or inhibit a motion or an action
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The glands of a normal endocrine system include:
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--1 pituitary gland (with two lobes) --1 thyroid gland (right and left lobes fused ventrally) --parathyroid glands (4 in most species) --2 adrenal glands --2 pancreas --1 thymus --1 pineal gland --2 gonads (ovaries in females, testes in males) |
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pituitary gland
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--located at the base of the brain just below the hypothalamus --also called the hypophysis because it is a growth located beneath or ventral to the hypothalamus |
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Why is the pituitary gland known as the master gland?
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it secretes many hormones that control or master other endocrine glands
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pituit/o
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pituitary gland |
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The pituitary gland acts in response to stimuli from the...
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hypothalamus
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Where is the hypothalamus located?
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below the thalamus in the brain
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What does the hypothalamus do?
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--secretes releasing and inhibiting factors that affect the release of substances from the pituitary gland --also produces antidiuretic hormone and oxytocin, which are released from the posterior pituitary gland |
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infundibulum
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--the stalk that connects the hypothalamus to the pituitary gland --the word means funnel-shaped passage or opening |
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What are the 2 lobes of the pituitary gland?
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--the anterior (cranial) lobe (aka adenohypophysis) --the posterior (caudal) lobe (aka neurohypophysis) |
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The anterior lobe of the pituitary gland does what? |
produces hormones |
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indirect-acting hormones
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hormones released from the anterior pituitary gland that cause their target organ to produce a second hormone
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aden/o
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gland
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The posterior lobe of the pituitary gland does what?
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it responds to a neurologic stimulus and does not produce hormones, but stores and secretes them
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direct-acting hormones
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hormones released from eh posterior pituitary gland that produce the desired effect directly in the target organ
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thyroid-stimulating hormone (TSH)
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augments growth and secretions of the thyroid gland
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adrenocorticotropic hormone (ACTH) |
augments the growth and secretions of the adrenal cortex
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follicle-stimulating hormone (FSH)
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--augments the secretion of estrogen and growth of eggs in the ovaries (female) and the production of sperm in the testes (male) --is a type of gonadotropic hormone |
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gonad/o
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gamete-producing gland (ovary or testes)
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-tropic |
means having an affinity for |
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luteinizing hormone (LH) |
--augments ovulation and aids in the maintenance of pregnancy in females --transforms an ovarian follicle into a corpus luteum, or yellow body --is a type of gonadotropic hormone |
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lute/o |
yellow |
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interstitial cell-stimulating hormone (ICSH)
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--stimulates testosterone secretion in males --is now considered to be LH (luteinizing hormone) |
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prolactin |
--augments milk secretion and influences maternal behavior --aka lactogenic hormone or luteotropin (sometimes abbreviated as LTH) |
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lact/o
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milk
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growth hormone (GH) |
--accelerates body growth --aka somatotropin (sometimes abbreviated as STH) |
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somat/o
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body
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melanocyte-stimulating hormone (MSH) |
augments skin pigmentation
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antidiuretic hormone (ADH)
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--maintains water balance in the body by augmenting water reabsorption in the kidneys --aka vasopressin (affects blood pressure) |
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anti-
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against |
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diuretic |
pertaining to increased urine secretion
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vas/o
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vessel
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press/i |
tension
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oxytocin
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stimulates uterine contractions during parturition and mild letdown from the mammary ducts
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What is the thyroid gland?
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a butterfly-shaped gland, with the right and left lobes fused ventrally by an isthmus (the isthmus may be rudimentary in horses and dogs)
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Where is the thyroid gland located? |
on either side of the larynx
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What does they thyroid gland regulate? |
metabolism, iodine uptake, and blood calcium levels |
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thyr/o thyroid/o |
thyroid
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triiodothyronine (T3) |
one of the thyroid hormones that regulates metabolism |
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thyroxin (T4)
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one of the thyroid hormones that regulates metabolism
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calcitonin
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thyroid hormone that promotes the absorption of calcium from blood into bones (lowers blood calcium and raises bone calcium levels)
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What are the parathyroid glands?
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4 glands located on the surface of the thyroid gland that secrete parathyroid hormone (or parathormone or PTH)
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para-
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near or before |
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What does parathyroid hormone (PTH) do?
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--regulate blood calcium and phosphorus levels --increases blood calcium levels by reducing bone calcium levels --regulates phosphorus content of blood and bones |
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How is calcium regulated?
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by the antagonistic actions of PTH and calcitonin
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parathyroid/o
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parathyroid glands |
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What are the adrenal or suprarenal glands?
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2 small glands located cranial to each kidney
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ad- |
toward
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ren/o
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kidney
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supra-
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above
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What does the adrenal gland regulate?
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electrolytes, metabolism, sexual functions, and they body's response to injury
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adren/o adrenal/o |
adrenal glands
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What are the 2 parts of the adrenal gland? |
--adrenal cortex (the outer portion) --adrenal medulla (the inner portion) |
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cortic/o |
outer
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medull/o |
inner or middle portion
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the adrenal cortex hormones are classified as steroids. What is a steroid?
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a substance that has a specific chemical structure of carbon atoms in four interlocking rings
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Corticosteroids
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steroids produced by the adrenal cortex
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mineralocorticoids |
group of corticosteroids that regulates electrolyte and water balance by affecting ion transport in the kidney
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aldosterone
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--a hormone that regulates sodium and potassium --the principal mineralocorticoid |
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glucocorticoids
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group of corticosteroids that regulates carbohydrate, fat, and protein metabolism; resistance to stress; and immunologic fuctioning
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hydrocortisone (or cortisol) |
--regulates carbohydrate, fat, and protein metabolism --it is a glucocorticoid |
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androgens
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group of corticosteroids that aids in the development and maintenance of male sex characteristics
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andr/o |
male
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-gen |
means producing
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anabolic steroids
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synthetic medications similar in structure to testosterone that are used to increase strength and muscle mass
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ana- |
up or excessive |
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bol/o
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throwing
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anabolic
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means pertaining to building up
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catabolism |
--means breaking down --the opposite of anabolism |
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cata-
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means down
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epinephrine |
--catecholamine that stimulates the sympathetic nervous system (the fight-or-flight system) and increases blood pressure, heart rate, and blood glucose --aka adrenaline --is known as a vasopressor since it increases blood pressure |
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catecholamines
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nitrogen-containing compounds that act as hormones or neurotransmitters
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vasopressor
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a substance that stimulates blood vessel contraction and increases blood pressure
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norepinephrine
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--catecholamine that stimulates the sympathetic nervous system (the fight-or-flight system) and increases blood pressure, heart rate, and blood glucose --aka noradrenaline --a substance very similar in chemical structure and function to epinephrine |
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epi- |
above |
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nephro/o
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kidney
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Where is epinephrine made?
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in the gland above the kidney
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ad- |
toward
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ren/o |
kidney
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Where is adrenaline made? |
the gland toward the kidney (the adrenal glands)
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nor-
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means normal and denote the parent compound in a pair of related substances
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What is the pancreas?
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an aggregation of cells near the proximal duodenum that has both exocrine and endocrine functions
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What are the exocrine functions of the pancreas?
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secretion of digestive enzymes
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What are the endocrine functions of the pancreas? |
secretion of blood glucose-regulating hromones
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pancreat/o
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pancreas
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islets of Langerhans |
specialized cells in the pancreas that secrete the hormones that help regulate blood glucose
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insulin
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--hormone that decreases blood glucose levels by transporting blood glucose into body cells or into storage as glycogen --it is secreted by the beta cells of the islets of Langerhans in response to high blood glucose |
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glycogen |
the main carbohydrate storage unit in animals
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glucagon |
--hormone that increases blood glucose levels by breaking down glycogen to glucose --it is secreted by the alpha cells of the islets of Langerhans in response to low blood glucose |
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What is the thymus? |
a gland predominant in young animas located near midline in the cranioventral portion of the thoracic cavity
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They thymus has an immunologic function through its role in...
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the maturation of T-lymphocytes
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thym/o |
thymus
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thymosin
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augments maturation of T-lymphocytes; therefore, it plays role in the immune system
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What is the pineal gland (or pineal body)?
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an aggregation of cells located in the central portion of the brain
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What is the function of the pineal gland?
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--functions are not fully understood --but one function is secretion of serotonin which is converted to melatonin, a hormone that affects circadian rhythm |
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pineal/o
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pineal gland
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melatonin |
controls circadian rhythm and reproductive timing
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circadian |
refers to the events occurring in a 24 hour period
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circa |
around
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diem |
day
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gonads |
gamete-producing glands
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gamete |
sex cell |
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ovaries
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gamete producing glands in females
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testes |
gamete producing glands in males |
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gonad/o |
gonad or gamete-producing gland
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gonadotropic hormones |
stimulate the gonads
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human chorionic gonadotropin (hCG)
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--stimulates secretions of the ovary --it is secreted by the embryo and by the placenta after implantation has occurred |
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estrogen |
hormone that aids in the development of secondary sex characteristics (an example is mammary gland development) and regulates ovulation in females
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--hormone that aids in the maintenance of pregnancy --is also secreted from the corpus luteum and placenta |
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testosterone
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--augments the development of secondary sex characteristics --examples of secondary sex characteristics in animals: horns in rams (not horns in all species), boar tusks, and shoulder girth in cattle and horses --it is also thought to be secreted from the ovaries and adrenal cortex, although those secretions are in very small amounts |
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ACTH stimulation test
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--blood analysis for cortisol levels after administration of synthetic adrenocorticotropic hormone --used to differentiate pituitary-dependent hyperadrenocorticism from adrenal-dependent hyperadrenocorticism |
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assays |
laboratory technique used to determine the amount of a particular substance in a sample
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dexamethasone suppression test (also called dex suppression test) |
--blood analysis for cortisol levels after administration of synthetic glucocorticoid (dexamethasone) --used to differentiate pituitary-dependent hyperadrenocorticism from adrenal-dependent hyperadrenocorticism --tests may be high or low dose |
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radioactive iodine uptake test
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--analysis of thyroid function after radioactive iodine has been given orally or intravenously --absorption of the radioactive iodine is measured with a counter for a specific time period |
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thyroid stimulation test
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--blood analysis for thyroid hormone levels after administration of synthetic thyroid-stimulating hormone --used to differentiate pituitary-dependent from thyroid-dependent dysfunction --TSH levels can also be measured before an dafter administration of thyrotropin-releasing hormone |
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synthetic |
pertaining to artificial production
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acromegaly
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enlargement of the extremities caused by excessive secretion of growth hormone after puberty |
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acr/o |
extremities |
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adrenopathy
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disease of the adrenal glands
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aldosteronism
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disorder caused by excessive secretion of aldosterone by the adrenal cortex, resulting in electrolyte imbalance
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electrolyte |
a charged substance found in blood
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diabetes insipidus (DI) |
insufficient antidiuretic hormone production or the inability of the kidneys to respond to ADH stimuli
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stimulus (plural is stimuli) |
an agent, act, or influence that produces a reaction
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diabetes mellitus (DM) |
metabolic disorder o inadequate secretion of insulin or recognition of insulin by the body, resulting in increased urination, drinking, and weight loss
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mellit/o
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means honey, which describes the "sweetness" of blood due to hyperglycemia in patients with diabetes mellitus
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ketoacidosis
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an abnormal condition of low pH accompanied by ketones (by-products of fat metabolism); may result from severe insulin deficiency
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ket/o
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means breakdown product of fat
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acidosis |
an abnormal condition of low pH
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endocrinopathy
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disease of the hormone-producing system
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gynecomastia |
condition of excessive mammary development in males
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gynec/o |
woman |
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mast/o |
mammary gland
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hyperadrenocorticism |
disorder caused by excessive adrenal cortex production of glucocorticoid, resulting in increased urination, drinking, and redistribution of body fat; aka Cushing's disease
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hypercrinism
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condition of excessive gland secretion
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hyperglycemia
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abnormally elevated blood glucose
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hypergonadism |
abnormal condition of excessive hormone secretion by the sex glands (ovaries in females; testes in males)
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hyperinsulinism |
disorder of excessive hormone that transports blood glucose to body cells
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hyperparathyroidism |
abnormal condition of excessive parathyroid hormone secretion resulting in hypercalcemia
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hyperpituitarism
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condition of excessive secretion of the pituitary gland
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--condition of excessive thyroid hormone --signs include increased metabolic rate, weight loss, polyuria, and polydipsia |
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hypoadrenocorticism
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disorder caused by deficient adrenal cortex production of glucocorticoid, resulting in weakness, vomiting, and weight loss; aka Addison's disease
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hypocrinism |
condition of deficient gland secretion
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hypoglycemia |
--abnormally low blood glucose --the brain is the first organ affected by hypoglycemia because metabolism in the brain depends primarily on glucose --signs include shakiness, anxiety, confusion, convulsions, seizures, and, if untreated, loss of consciousness |
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hypogonadism
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abnormal condition of deficient hormone secretion by the sex glands (ovaries in females; testes in males)
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hypoparathyroidism |
abnormal condition of deficient parathyroid hormone secretion resulting in hypocalcemia
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hypocalcemia
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abnormally low levels of blood calcium
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hypo-
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deficient |
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calc/i |
calcium
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-emia |
blood condition
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hypercalcemia |
abnormally high blood calcium levels
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hyper- |
excessive
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hypopysitis |
inflammation of the pituitary gland
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hypothyroidism |
--condition of thyroid hormone deficiency --signs include decreased metabolic rate, poor hair coat, lethargy, increased sensitivity to cold |
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euthyroidism |
condition of normal thyroid function
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eu- |
good, well, or easily
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insulinoma |
tumor of the islet of Langerhans of the pancreas
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inflammation of the pancreas
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pheochromocytoma |
--tumor of the adrenal medulla resulting in increased secretion of epinephrine and norepinephrine --it is a tumor that takes on a dark (dusky) color because it is composed of chromaffin (or colored) cells |
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phe/o |
dusky
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chrom/o |
color
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cyt/o |
cell
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-oma |
tumor
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pinealopathy
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disorder of the pineal gland
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pituitarism
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any disorder of the pituitary gland
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thymoma |
tumor of the thymus
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thyroiditis
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inflammation of the thyroid gland
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thyromegaly |
enlargement of the thyroid gland
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thyrotoxicosis |
abnormal life-threatening condition of excessive, poisonous quantities of thyroid hormones
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toxic/o |
poison
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adrenalectomy
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surgical removal of one or both adrenal glands
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chemical thyroidectomy
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administration of radioactive iodine to suppress thyroid function; aka radioactive iodine therapy
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hypophysectomy |
surgical removal of the pituitary gland
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lobectomy |
surgical removal of the pituitary gland
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pancreatectomy
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surgical removal of the pancreas
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pancreatotomy |
surgical incision into the pancreas
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parathyroidectomy
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surgical removal of one or more parathyroid glands
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pinealectomy |
surgical removal of the pineal gland
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thymectomy |
surgical removal of the thymus
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thyroidectomy |
surgical removal of all or part of the thyroid gland
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ACTH |
adrenocorticotropic hormone
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ADH |
antidiuretic hormone
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DI |
diabetes insipidus
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DM |
diabetes mellitus
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FSH |
follicle-stimulating hormone
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GH |
growth hormone
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GLU |
glucose
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hCG |
human chorionic gonadotropin
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ICSH
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interstitial cell-stimulating hormone
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LH
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luteinizing hormone
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LTH
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luteotropin hormone
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MSH |
melanocyte-stimulating hormone
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PTH
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parathyroid hormone
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STH |
somatotropin hormone
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T3 |
triiodothyronine
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T4 |
thyroxine
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TSH |
thyroid-stimulating hormone
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