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32 Cards in this Set

  • Front
  • Back
phelbo
vein
angio
vessel
ectomy
to surgically remove
the absorption of the antiosteoporosis drug ____________ is decreased 60% with coffee or juice. IT is NOT absorbed at all when ingested with a meal. Absorptionis optimal if taken 2 hours before food
alendronate (Fosamax)
A high fiber diet may decrease the absorption of tricyclic antidepressants such as ___________
amitriptyline (elavil)
_____________ forms an insoluble complex with Ca in some dairy products; Ca, Fe, Mg, or Zn in supplements; or Ca, Al, and/or Mg antacids, decreasing drug absorption
ciprofloxacin (cipro)
The absorption of ________ is significantly higher when given with food than when fasting
cefuroxime axetil (ceftin)
hypoalbuminemia provides fewer binding sites for highly protein bound drugs such as ______ and ________. Therefore a higher free fraction of drug is availble, resulting in increased drug effects . For warfarin this could induce bleeding, while higher phenytoin levels could cause toxicity.
phenytoin (dilantin) and warfarin ( coumadin)
Concurrent ingestion of food and _______ reduces first pass metabolism of the drug. This is result in higher serum drug levels.
propranolol(Inderal)
Grapefruit inhibits metabolism of antihyperlipidemic HMG CoAreductoase inhibitors, ex __________ , by cytochrome P450 3A4 ospemzu,es om tje omtestoma; wall, raising drug blood levels
atrovastatin (lipitor)
______ and sodium compete for tubular reabsorption in the kitney. High sodium intake causes more _____ to be excreated. Low sodium intake will cause the kidney to retain _____, raising blood levels
lithium
Antibiotics _____ and ______ chelate with divalent or trivalent cations, Ca, Mg, Fe, Zn.
tetracycline and cipro
antihyperlipidemic, bile acid sequestrant ___________ adsorbs fat soluble vitamins A,D, E, K
cholestyramine (Questran)
Prolonged use of antiulcer drugs such as ________ may decrease absorption of vitamin B12, thiamin, and Fe
cimetidine (tagament)
MEdication induced mucosal damage by _________ may cause decreased nutrient absopriton
antieoplastic drugs
Anticonvulsants ________ and ________ increase the metabolism of folic acid, vitamins D and K
phenobarbital and phenytoin(Dilantin)
____________ inhibits the conversion of pyridoxine ( vitamin B6) deficiency and peripheral neuropathy unless a B6 supplement is also prescribed
antituberculosis drug isonaizid (INH)
Loop diuretics, such as ________ increase excretion of Na, K, Cl, Mg, Ca.
furosemide (Lasix)
_______ increase excretion of most electrolytes, but decrease excretion of Ca due to renal reabsorption
Thiazide diuretics
high caffeine intake may increase the adverse effects of _______ ( nervousness, tremor, insomnia)
theophylline
Tyramine, dopamine, or other vasoconstrictors in food enhace the toxic effects of MAOIs such as ______________ . This effect may cause a hypertensive crisis, which can be fatal
tranylcypromine sulfate (parnate)
Vitamin K aids the production of clotting factos in direct opposition to the action of ______
warfarin (coumadin)
____ is a stimulant which counteracts the antianxiety effects of tranquilizers
caffeine
high fat diet counteracts the effect of antihyperlipidemic drugs such as ________ or ______
lovastatin (mevacor) or gemfibrozil (lopid)
Ticyclic antidepressants such as _______ cause dry mouth and sour or metallic taste
amitriptyline (elavil)
the anitbiotic _______ enters the saliva causes a bitter taste
clarithromycin (biaxin)
Antibiotics, such as _______, may result in oral yeast overgrowth i.e. candidiasis
tetracycline
Antibiotic ___________ causes metallic taste in the mouth
metronidazole (flagyl)
sThe cytotoxic effects of antineoplastics such as ______ or _____causes stomatitis, glossitis, and esophagitis
cisplatin or methotrexate
Nonsteroidal anti-inflammatory NSAID such as ________, _______ and _______ cause stomach irritation, sometimes leading to sudden, serious gastric bleeding.
acetylsalicylic acid (asprin), ibuprofen (advil, motrin) and naproxen (aleve, anaprox)
_________ slow peristalsis causing constipation
anticholinergenic drugs ( antipsychotics, antidepressants, and antihistamines)
antiboitics ( ________ cause over growth of clostridium difficile and result in pseudomembranous colitis
cipro