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32 Cards in this Set
- Front
- Back
phelbo
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vein
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angio
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vessel
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ectomy
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to surgically remove
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the absorption of the antiosteoporosis drug ____________ is decreased 60% with coffee or juice. IT is NOT absorbed at all when ingested with a meal. Absorptionis optimal if taken 2 hours before food
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alendronate (Fosamax)
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A high fiber diet may decrease the absorption of tricyclic antidepressants such as ___________
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amitriptyline (elavil)
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_____________ forms an insoluble complex with Ca in some dairy products; Ca, Fe, Mg, or Zn in supplements; or Ca, Al, and/or Mg antacids, decreasing drug absorption
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ciprofloxacin (cipro)
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The absorption of ________ is significantly higher when given with food than when fasting
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cefuroxime axetil (ceftin)
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hypoalbuminemia provides fewer binding sites for highly protein bound drugs such as ______ and ________. Therefore a higher free fraction of drug is availble, resulting in increased drug effects . For warfarin this could induce bleeding, while higher phenytoin levels could cause toxicity.
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phenytoin (dilantin) and warfarin ( coumadin)
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Concurrent ingestion of food and _______ reduces first pass metabolism of the drug. This is result in higher serum drug levels.
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propranolol(Inderal)
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Grapefruit inhibits metabolism of antihyperlipidemic HMG CoAreductoase inhibitors, ex __________ , by cytochrome P450 3A4 ospemzu,es om tje omtestoma; wall, raising drug blood levels
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atrovastatin (lipitor)
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______ and sodium compete for tubular reabsorption in the kitney. High sodium intake causes more _____ to be excreated. Low sodium intake will cause the kidney to retain _____, raising blood levels
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lithium
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Antibiotics _____ and ______ chelate with divalent or trivalent cations, Ca, Mg, Fe, Zn.
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tetracycline and cipro
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antihyperlipidemic, bile acid sequestrant ___________ adsorbs fat soluble vitamins A,D, E, K
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cholestyramine (Questran)
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Prolonged use of antiulcer drugs such as ________ may decrease absorption of vitamin B12, thiamin, and Fe
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cimetidine (tagament)
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MEdication induced mucosal damage by _________ may cause decreased nutrient absopriton
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antieoplastic drugs
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Anticonvulsants ________ and ________ increase the metabolism of folic acid, vitamins D and K
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phenobarbital and phenytoin(Dilantin)
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____________ inhibits the conversion of pyridoxine ( vitamin B6) deficiency and peripheral neuropathy unless a B6 supplement is also prescribed
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antituberculosis drug isonaizid (INH)
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Loop diuretics, such as ________ increase excretion of Na, K, Cl, Mg, Ca.
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furosemide (Lasix)
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_______ increase excretion of most electrolytes, but decrease excretion of Ca due to renal reabsorption
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Thiazide diuretics
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high caffeine intake may increase the adverse effects of _______ ( nervousness, tremor, insomnia)
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theophylline
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Tyramine, dopamine, or other vasoconstrictors in food enhace the toxic effects of MAOIs such as ______________ . This effect may cause a hypertensive crisis, which can be fatal
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tranylcypromine sulfate (parnate)
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Vitamin K aids the production of clotting factos in direct opposition to the action of ______
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warfarin (coumadin)
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____ is a stimulant which counteracts the antianxiety effects of tranquilizers
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caffeine
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high fat diet counteracts the effect of antihyperlipidemic drugs such as ________ or ______
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lovastatin (mevacor) or gemfibrozil (lopid)
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Ticyclic antidepressants such as _______ cause dry mouth and sour or metallic taste
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amitriptyline (elavil)
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the anitbiotic _______ enters the saliva causes a bitter taste
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clarithromycin (biaxin)
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Antibiotics, such as _______, may result in oral yeast overgrowth i.e. candidiasis
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tetracycline
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Antibiotic ___________ causes metallic taste in the mouth
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metronidazole (flagyl)
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sThe cytotoxic effects of antineoplastics such as ______ or _____causes stomatitis, glossitis, and esophagitis
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cisplatin or methotrexate
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Nonsteroidal anti-inflammatory NSAID such as ________, _______ and _______ cause stomach irritation, sometimes leading to sudden, serious gastric bleeding.
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acetylsalicylic acid (asprin), ibuprofen (advil, motrin) and naproxen (aleve, anaprox)
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_________ slow peristalsis causing constipation
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anticholinergenic drugs ( antipsychotics, antidepressants, and antihistamines)
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antiboitics ( ________ cause over growth of clostridium difficile and result in pseudomembranous colitis
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cipro
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