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195 Cards in this Set

  • Front
  • Back
electrolyte
mineral salt (sodium, potassium, and calcium) that carries an electrical charge in solution
glucagon
hormone produced by pancreatic alpha cells that stimulates the liver to change stored glycogen to glucose (opposes insulin)
ductless glands of endocrine system
pituitary, thyroid, parathyroid, adrenal, pancreatic, pineal, thymus glands, and ovaries and testis
glucose
simple sugar that is the end product of carb digestion
insulin
hormone produced by pancreatic beta cells that allows body cells to use glucose for energy or store it in the liver as glycogen
sympathomimetic
agent that mimics the effects of the sns
The master gland
pituitary!
adenohypophysis (triggered by hypothalamus) - produces adrenocorticotropic hormone, follicle-stimulating hormone, growth hormone, lutenizing hormone, prolactin, and thyroid stim (TSH)
neurophypophysis stores and secretes two hormones produced by hypothalamus: antidiuretic hormone and oxytocin
Thyroid gland
Calcitonin
Thyroid hormone - thyroxine (T4) and triiodothyronine (T3)
calcitonin
Ca+ levels... decreases reabsorption of calcium and phosphate from bones to blood
thyroxine and triiodothyronine
increases energy production from all food types
increases rate of protein synthesis
ACTH
adrenal cortex - promotes secretion of corticosteroids, esp. cortisol
from anterior pituitary
FSH
anterior pituitary - follicle-stimulating
ovaries - stimulates egg production, increases secretion of estrogen
testes - stimulates sperm production
Growth Hormone
from anterior pituitary - GH or somatotropin
regulates growth of bone, muscle, and other body tissues
increases use of fats for energy
hyposecretion causes dwarfism
hypersecreation during childhood causes gigantism, during adulthood causes acromegaly
luteinizing hormone
from adenohypophysis - LH
ovaries - promotes ovulation, production of estrogen and progesterone
testes - secretion of testosterone
prolactin
from adenohypophysis - PRL
breast - in conjunction with other hormones, promotes lactation
hypersecretion in nursing mothers causes excesssive secretion of milk (galactorrhea)
thyroid-stimulating hormone
from adenohypophysis (TSH or thyrotropin)
thyroid gland - stimulates secretion of thyroid hormones
antidiuretic hormone
from neurohypophysis - ADH
kidney - increases water reabsorption
hyposecretion - diabetes insipidus
hyper - syndrome of inappropriate antidiuretic hormone
oxytocin
from neurohypophysis
uterus - uterine contractions, labor
breast - promotes milk secretion from mammary glands
Parathyroid glands
posterior surface of lobes of thyroid
secretes PTH
Parathyroid hormone
from parathyroid glands - PTH
bones - increases reabsorption of calcium and phosphate from bone to blood
kidneys - increases calcium absorption and phosphate excretion
small intestine - increases absorption of calcium and phosphate
hypo - tetany
hyper - osteitis fibrosa cystica
Adrenal glands
aka suprarenal
Cortex - mineralcorticoids (aldosterone), glucocorticoids (cortisol), sex hormones (androgens, estrogens, progestins)

Adrenal medulla - epinephrine and norepinephrine
Glucocorticoids
from Adrenal cortex
mainly cortisol
body cells - promote gluconeogenesis; regulate metabolism of carbohydrates, proteins, and fats, and help depress inflammatory and immune responses
Mineralocorticoids
from adrenal cortex
mainly aldosterone
kidneys - increase blood levesl of sodium and decrease blood levels of potassium in the kidneys
Sex hormones from adrenal cortex
androgens, estrogens, or related steroid hormones produced by the ovaries, testes, and adrenal cortices
in females, possibly responsible for female libido and source of estrogen after menopause
hypersecretion of adrenal androgen in females - virulism
hyper of adrenal estrogen and progestin in males - feminization
hypo - no known effect
epinephrine and norepinephrine
from adrenal medulla
sns target organs - hormone effects mimic sns activation (sympathomimetic), increase metabolic rate, heart rate, and raise bp by promoting vasoconstriction
hypo - no known effect
hyper - prolonged fight/flight and hypertension
Pancreas
endocrine and exocrine gland. exocrine - digestive secretions from pancreas to small intestines
endocrine through islets of Langerhans:
glucagon - alpha cells
Insulin - beta cells
insulin target organs and functions and disorders
tissue cells - lowers blood glucose lvl by accelerating glucose transport into cells and the use of that glucose for energy production
hypo - diabetes mellitus
hyper - hyperinsulinism
glucagon target organ and functions and disorders
liver and blood - raises blood glucose lvl by accellerating conversion of glycogen into glucose in the liver (glycogenolysis) and other nutrients into glucose in the liver (gluconeogenesis) and releaseing glucose into blood (glycogen to glucose)
a deficiency may cause persistently low blood glucose levels (hypoglycemia)
Pineal gland
posterior part of third ventricle of brain
... secretes melatonin? may inhibit activities of ovaries
adren/o
adrenal/o
adrenal glands
adrenomegaly - enlargement of adrenal glands
calc/o
calcium
hypercalcemia - excessive calcium in blood
crin/o
secrete
gluc/o
glyco/o
glycos/o
sugar, sweetness
homeo
same, alike
kal/i
potassium
kalemia - potassium in the blood
pancreat/o
pancreas
pancreatomy - incision of pancreas
thym/o
thymus gland
thymoma - tumor of
thryo
thyroid/o
thyroid gland
toxic/o
poison
-crine
secrete
endocrine -secrete within
-dipsia
thirst
polydipsia - excessive thirst
-gen
forming, producing, origin
-toxic
pertaining to poison
-uria
urine
glycosuria - glucose in the urine
eu-
good, normal
exo-
outside, outward
hyper-
excessive, above normal
hyperglycemia
cretinism
hypothyroidism in infants
leads to mental retardation, impaired growth, low body temp, and abnormal bone formations
myxedema
hypothyroidism that develops during adulthood
edema, low blood levels of T3 and T4, weight gain, cold intolerance, fatigue, depression, muscle or joint pain, and sluggishness
Graves disease
hyperthyroidism
elevated metabolic rate, abnormal weight loss, excessive perspiration, muscle weakness and emotional instability
exophthalamos - bulging eyes from edematous swelling
goiter
toxic goiter
hyperthyroidism
from excessive TSH from pituitary?
enlarged thyroid gland
hypoparathyroidism
from parathyroid dysfunciton or elevated blood calcium levels
effect - decreased blood calcium level (hypocalcemia), causing muscle twitches and spasms (tetany)
hyperparathyroidism
caused by benign tumor
increased PTH secreation
demineralization of bones (osteitis fibrosa cystica), making them porous (osteoporosis) and highly susceptible to fracture and deformity
causes calcium deposits in the kidneys
Disorder known as von Recklinghausen disease when generalized and all bones are affected. renal symptoms and kidney stones (nephrolithiasis) may develop
Addison Disease
deficiency of cortical hormones
Body can't properly handle internal and external stress
Sodium and potassium metabolsism disturbed - severe chronic dehydration
muscle weakness, anorexia, gastrointestinal symptoms, fatigue, hypoglycemia, hypotension, low blood sodium (hyponatremia) and high serum potassium (hyperkalemia)
With early treatment (adrenocortical hormone therapy), prognosis is excellent. Untreated... progressive deterioration
Cushing syndrome
excessive cortisol, Adrenocorticotropic hormone, or both circulating in blood
from long-term steroid drugs, adrenal tumor, cushing disease - pituitary disorder caused by hypersecretion of ACTH from an adenoma
alters carb and protein metabolism and electrolyte balance. Overproduction of mineralcorticoids and glucocorticoids causes blood glucose concentration to remain high, depleting tissue protein. Edema, weight gain, structural changes (moon shaped face, exaggerated head and trunk and pencil thin arms and legs), fatigue, high blood pressure, excessive hair growth
Pheochromocytoma
neoplasm in adrenal medulla
excessive epinephrine and norepinephrine
high blood pressure, rapid heart rate, stress, fear, palpitations, headachs, visual blurring, muscle spasms, and sweating
Most common pancreatic disorder
most common - diabetes mellitus
impaired carbohydrate, protein, and fat metabolism due to insufficient production of insulin or the body's inability to use insulin properly
fat metabolism produces ketones, which enter blood (ketosis)
without insulin - hyperglycemia. Beyond level tolerated by kidneys, glucose "spills" into the urine (glucosuria), and is expelled along with electrolytes, particularly sodium -> muscle weakness and fatigue. Cellular starvation results and leads to hunger and an increased appetite (polyphagia)
genetics and environmental factors
type 1 and type 2
Type 1 diabetes
usually in children and young adults
insufficient insulin
treat with balanced diet, exercise, and insulin injections
may use insulin pump
Type 2 diabetes
most common, onset later in life, though obesity is increasing prevalence in children
Deficient in producing sufficient insulin, or body's cells are resistant to insulin action in target tissues
hyperglycemia - damage kidneys, eyes, nerves, or heart
treat - exercise, diet, weight loss, if needed insulin or oral antidiabetic agents
Complications of diabetes
primary - diabetic ketoacidosis (diabetic coma, too little insulin)
secondary - diabetic retinopathy (vision loss) and nephropathy (renal insufficiency)
Gestational diabetes - develop inability to metabolize carbs during pregnancy, usually resolves after childbirth
Pancreatic cancer
epithelial tumors - adenocarcinomas
Pain in head, body, or tail of organ
4th leading cause of cancer death in US
Pituitary Tumors
some cause excessive production of hormones
others restrict normal function, lower hormones
most are noncancerous - adenomas
can compress nearby nerves, resulting in vision problems
Treatment - remove tumor, restore hormone levels or radiation therapy to shrink tumor
Thyroid carcinoma
in general - radiation, prolonged TSH stimulation, familial disposition, and chronic goiter are presdisposing factors
large tumor - hypothyroidism
sometims stimulates production - hyperthyroidism
surgical removal, radiation, or both
acromegaly
rare hormonal disorder in adulthood, usually caused by a GH-secreting pituitary tumor (adenoma) that promotes the soft tissue and bones of the face, hands, and feet to grow larger than normal
diuresis
increased formation and secretion of urine
occurs in diabetes mellitus, diabetes insipidus, and acute renal failure
glycosuria
abnormal amount of glucose in the urine
Graves disease - short definition
multisystem autoimmune disorder characterized by pronounced hyperthyroidism usually associated with enlarged thyroid gland and exophthalamos (eyeball protrusion)
Hirsutism
excessive distribution of body hair, esp in women
hypercalemia
condition in which the calcium level in the blood is higher than normal
overactivity in parathyroid gland/s, or cancer, medical disorders, medications, and excessive use of calcium and vit D supplements
hyperkalemia
higher potassium level in blood
potentially life threatening - cardiac arrest and death
hypervolemia
abnormal increase in volume of blood plasma
from retention of sodium and water by kidneys
Hyponatremia
low sodium level in blood
excessive fluid
insulinoma
tumor of the islets of Langerhans in the pancreas
obesity

morbid obesity
excessive accumulation of fat that exceeds the body's skeletal and physical standards, usually 20 % above ideal

morbid - BMI of 40 or greater, 100 lb or more over ideal
panhypopituitiarism
total pituitary impairment that brings about a progressive and general loss of hormone activity
pheochromocytoma
small chromaffin cell tumor, usually located in adrenal medulla, causing elevated heart rate and blood (pressure?)
thyroid storm
crisis of uncontrolled hyperthyroidism caused by the release into the bloodstream of an increased amount of thyroid hormone, also called thyroid crisis or thyrotoxic crisis
virilism
masculinization or development of male secondary sex characteristics in a woman
exophthalmometry
measures the degree of forward displacement of the eyeball (exophthalmos) as seen in Graves disease
parathyroidectomy
excision of one or more parathyroid glands, usually to control hyperparathyroidism
transsphenoidal hypophysectomy
endoscopic procedure to surgically remove a pituitary tumor through an incision in the sphenoid sinus without disturbing brain tissue
treat Cushing syndrome due to tumor
thymectomy
excision of the thymus gland
treatment of myasthenia gravis
Thyroidectomy
excision of the entire thyroid gland, part, or a single lobe
for goiter, tumors, or hyperthyroidism
fasting blood sugar
test that measures glucose levels in a blood sample following a fast of at least 8 hours
glucose tolerance test
GTT - screening test in which a dose of gluocose is administered and blood samples are taken afterward at regular intervals to determine how quickly glucose is cleared from the blood
diagnose pre-diabetes and gestational diabetes
insulin tolerance test
ITT - diagnostic test in which insulin is injected into the vein to assess pituitary function, adrenal funciton, and determine insulin sensitivity
thyroid function test
TFT - test that detects an increase or decrease in thyroid funciton
lvls of TSH, T3, and T4
total calcium test
measures calcium to detect bone and parathyroid disorders
computed tomography
CT
imaging technique that rotates an x-ray emitter around the area to be scanned and measures the intensity of transmitted rays from different angles
cross-sectional image
magnetic resonance imaging
MRI
noninvasive imaging technique that uses radio waves and a strong magnetic field, rather than an x-ray beam, to produce multiplanar cross-sectional images
good soft-tissue contrast, multiple plane views
radioactive iodine uptake
RAIU
administration of a radioactive iodine in pill or liquid form is used as a tracer to test how quickly the thyroid gland takes up iodine from the blood
assess thyroid function
thyroid scan
images of the thyroid gland are obtained after oral or intravenous administration of a small dose of radioactive iodine
id nodules and tumors
antidiuretics
reduce or control excretion of urine
vasopressin
antithyroids
treat hyperthyroidism by impeding the formation of T3 and T4 hormone
methimazole
strong iodine solution
corticosteroids
replace hormones lost in adrenal insuficiency
cortisone
hydrocortisone
growth hormone replacements
increase skeletal growth in children and growth hormone deficiencies in adults
somatropin
insulins (drugs)
lower blood glucose by promoting its entrance into body cells and converting glucose to glycogen
regular insulin
NPH insulin
insulin aspart
oral antidiabetics
treat type 2 diabetes mellitus by stimulating the pancreas to produce more insulin and decrease peripheral resistance to insulin
glipizide, metformin
thyroid supplements
replace or supplement thyroid hormones
levothyroxine
liothyronine
DKA
diabetic ketoacidosis
FBS
fasting blood sugar
HRT
hormone replacement therapy
androgen
generic term for an agent (usually a hormone such as testosterone and adrosterone) that simulates developments of male characteristics
also regulate production of sebum
ductule
very small duct!
homeostasis
state in which the regulatory mechanisms of the body maintain an internal environment within tolerable levels, despite changes in external env.
temp, acidity, and concentration of salt, food, and waste products
synthesize
forming a complex substance by the union of simpler compounds or elements
stratum corneum
superficial layer of the epidermis composed of dead, flat cells that lack a blood supply and sensory receptors
thickness depends on wear on that area
stratum basal (basal layer)
basal layer of cells in epidermis
only layer composed of living cells where new cells are formed
as cells move, filled with keratin for waterproofing
about 1 month from formation to sloughing
in basal layer, melanocytes produce melanin
dermis
aka corium
living tissue with capillaries, lymph, nerve endings, hair follicles, sebaceous (oil) glands, and sudoriferous (sweat) glands
subcutaneous layer
aka hypodermis
binds dermis to underlying structures
loose connective tissue and adipose interlaced with blood vessels
stores fates, insulates and cushions body, and regulates temp
Sebum
oily secretion from sebaceous gland
acidic - destroys harmful organisms
when ductules are blocked, acne forms from congested sebum
sex hormones regulate production and secretion
glands everywhere except palms and soles
steat/o
also adipo, lipo
fat
lipocele - hernia containing fat
steatitis - inflammation of fatty tissue
element meaning skin
cutaneo, dermato, dermo
hidr/o
sweat, also sudor/o
hidradenitis - inflammation of the sweat glands
sudoresis - profuse sweating, aka hyperhidrosis
ichthy/o
dry, scaly
kerato
horny tissue, hard, cornea
keratosis - abnormal condition of horny tissue, thickened area of epidermis or any horny growth on skin, such as a callus or wart
melano
black
myc/o
fungus
onych/o
ungu/o
nail
onychomalacia - softening of the nails
ungual - pertaining to the nails
like ungulate!
pil/o
trich/o
hair
pilonidal - pertaining to hair in a nest
trichopathy - disease involving the hair
scler/o
hardening, sclera
scleroderma - hardening of the skin
seb/o
sebum, sebaceous
seborrhea - discharge of sebum
squam/o
scale
squamous - pertaining to scales
xen/o
foreign, strange
xenograft - skin transplantation from a foreign donor

xenophilious lovegood!
xero
dry
xeroderma - dry skin
-cyte
cell
-derma
skin
pyoderma - pus in the skin
Lesions
primary and secondary
tissue pathologically altered by injury, wound, or infection
primary - initial reaction to pathologically altered tissue, may be flat or elevated
secondary - changes due to infection, scratching, trauma or various stages of disease
lesions described by appearance, color, location and size
Burns
caused by contact with thermal, chemical, electrical, or radioactive agents
1st/superficial - only epidermis, local effects (erythema and hypersethesia)
2nd/partial thickness - epidermis and part of dermis, vesicles or bullae form and may heal with little or no scarring
3rd/full-thickness - epidermis and dermis destroyed, some underlying connective tissue damaged and maybe bones muscles and tendons
ulcerating wounds develop, scar tissue
body surface area affected estimated with rule of nines (9% and 18%)
neoplasms
abnormal growth of tissue classified as benign or malignant
benign neoplasms
noncancerous growths of the same type of cells as the tissue in which they are growing
may harm through pressure
malignant neoplasms
caner
cells that tend to become invasive and spread to remote regions of the body (metastasis). enter blood and lymph and travel to form secondary tumor sites
cancer treatment includes surgery, chemotherapy, immunotherapy (biotherapy - stimulate body's own immune defenses), and radiation therapy
Tumor grading
Grade I - tumor cells well differentiated, closely resemble tissue of origin and retain functions
Grade II - tumor cells moderately or poorly differentiated, less resemblance, more variation in size/shape of cells, increased mitoses
Grade III - tumor cells poorly differentiated, increased abnormality in appearance, marked variation in shape/size, greatly increased mitoses,
Grade IV - tumor cells very poorly differentiated, abnormal appearance to the extent that recognition of the tumor's tissue origin is difficult, extreme variation in size and shape of tumor cells
Tumor staging
tumor-node-metastasis (TNM) system most common
classifies by size and degree of spread
T - size and invasiveness of primary tumor (T1 small, T4 large and invasive)
N - area lymph nodes involved (NX, N0, N1-4)
M - invasiveness (metastasis) of primary tumor (MX, M0, M1 - presence of metastasis
numbers indicate size or spread
Basal cell carcinoma
most common skin cancer
from overexposure to sunlight usually
locally invasive, but rarely metastasize
Squamous cell carcinoma
from skin that undergoes pathological hardening (keratinizing) of epidermal cells
Invasive tumor with potential for metastasis, most common in fair skinned white men over age 60
confined - in situ
penetrating - invasive
treatment - surgical excision, curettage and electrodesiccation, radiation therapy, chemotherapy
malignant melanoma
malignant growht of malanocytes
highly metastic - to liver, lungs, or brain
Sun!
requires surgery and adjuvant therapies
abscess
localized collection of pus at the site of an infection (staphylococcal)
in hair follicle - furuncle or boil
subcutaneous - carbuncle
alopecia
partial or complete loss of hair resulting from normal aging, an endocrine disorder, a drug reaction, anticancer medication, or a skin disease
baldness
Bowen disease
form of intraepiderma carcinoma (squamous cell) characterized by red-brown scaly or crusted lesions that resemble a patch of psoriasis or dermatitis
cellulitis
diffuse, acute infection of the skin and subcutaneous tissue
light glossy appearance of the skin, localized heat, redness, pain, swelling, and occasionally fever, malaise, and chills
chloasma
pigmentary skin discoloration usually occurring in yellowish brown patches or spots
comedo
typical small skin lesion of acne vulgaris caused by accumulation of keratin, bacteria, and dried sebum plugging an excretory duct of the skin
closed form - whitehead
dermatomycosis
infection of the skin caused by fungi
ringworm
ecchymosis
skin discoloration consisting of a large, irregularly formed hemorrhagic area with colors changing from blue-black to greenish brown or yellow, commonly called a bruise
eczema
chronic inflammatory skin condition characterized by erythema, papules, vesicles, pustules, scales, crusts, and scabs and accompanied by intense itching (pruritis), aka atopic dermatitis
erythema
redness of the skin caused by swelling of the capillaries
sunburn or nervous blushing
eschar
dear matter that is sloughed off from the surface of the skin
impetigo
bacterial skin infection characterized by isolated pustules that become crusted and rupture
keratosis
thickened area of epidermis or any horny growth on the skin
lentigo
small brown macules, esp on the face and arms, broght on by sun exposure, usually in a middle-aged or older person
pallor
unnatural paleness or abscence of color in skin
pediculosis
infestation with lice, transmitted by personal contact or common use of brushes, combs, or headgear
Petechia
minute, pinpoint hemorrhage under the skin
pressure ulcer
inflammation, sore, or skin deterioration caused by prolonged pressure (prevented blood flow)
decubitus ulcer
stage 1 to 4
pruritus
intense itching
psoriasis
chronic skin disease characterized by circumscribed red patches covered by thick, dry, silvery, adherent scales and caused by excessive development of the basal layer of the epidermis
purpura
any of several bleeding disorders characterized by hemorrhage into tissues, particularly beneath the skin or mucous membranes, producing ecchymoses or petachia
scabies
contagious skin disease transmitted by the itch mite, commonly through sexual contact
tinea
fungal skin infection whose name commonly indicates the bod part affected, also called ringworm
tinea pedis - athlete's foot
urticaria
allergic reactions of the skin characterized by the eruption of pale red elevated patches called wheals or hives
verruca
epidermal growth caused by a virus, aka warts
plantar, juvenile, and venereal warts
vitiligo
localized loss of skin pigmentation characterized by milk-white patches
chemical peel
chemical removal of outer layers of skin to treat acne scarring and general keratoses
cryosurgery
use of subfreezing temperatures to destroy or eliminate abnormal tissue such as tumors, warts, and unwanted, cancerous, or infected tissue
debridement
removal of necrotized tissue from a wound by surgical excision, enzymes, or chemical agents
or maggots!
promote healing and prevent infection
dermabrasion
rubbing (abrasion) using wire brushes or sandpaper to mechanically scrape away the epidermis
fulguration
tissue destruction by means of high-frequency electric current; aka electrodesiccation
for tumors and lesions
photodynamic therapy
PDT
procedure in which cells selectively treated with an agent called a photosensitizer are exposed to light to produce a reaction that destroys the cells
cancer, actinic keratosis, and macular degeneration
biopsy
representative tissue sample removed from a body site for microscopic examination
diagnosis, estimate prognosis, or follow course of disease
frozen section, needle, punch, or shave
Mohs
layers of cancer-containing skin are progressively removed and examined until only cancer-free tissue remains
skin graft
transplantation of healthy tissue to an injured site
allograft - one person to another, homograft
autograft - within individual
synthetic - artificial skin
xenograft - foreign donor (usually a pig), heterograft
allergy skin test
test in which a suspected allergen or sensitizer is applied to or injected into the skin to determine the patient's sensitivity to it
intradermal - subcutaneous injections
patch - taped to skin
scratch - aka puncture or prick test
culture and sensitivity
(C&S)
lab test that grows a colony of bacteria removed from an infected area in order to identify and determine sensitivity to antibiotics
antifungals
alter the cell wall of fungi or disrupt enzyme activity
ringworm, athlete's foot, fungal infection of the nail (onchomycosis)
nystatin
itraconazole
antihistamines
inhibit allergic reactions of inflammation, redness, and itching caused by the release of histamine
antiparasitics
kills insect parasites, such as mites and lice
antiseptics
topically applied agents that inhibit growth of bacteria, thus preventing infections in cuts, scratches, and surgical incisions
corticosteroids
decrease inflammation and itching by suppressing the immune system's inflammatory response
keratolytics
destroy and soften the outer layer of skin so that it is sloughed off or shed
strong keratolytics remove warts and corns
protectives
cover, cool, dry, or soothe inflammed skin
protectives do not penetrate the skin or soften it, rather they allow the natural healing process to occur by forming a long-lasting film that protects the skin from air, water, and clothing
lotions
ointments
topical anesthetics
block sensation of pain by numbing the skin layers and mucous membranes
bx
biopsy
BCC
basal cell carcinoma
C&S
culture and sensitivity
CA
cancer, chronological age, cardiac arrest
FS
frozen section
ID
intradermal
I&D
incision and drainage
IMP
impression (synonymous with diagnosis)
IV
intravenous
TNM
tumor-node-metastasis
ung
ointment
XP, XDP
xeroderma pigmentosum
What happens in lymph nodes
macrophages phagocytze bacteria and other harmful material while T cells and B cells exert their protectie influence
spleen resembles a lymph node becaue it acts as a filter by removing cellular debris, bacteria, parasites, and other infectious agents