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70 Cards in this Set

  • Front
  • Back
to control the symptoms of cancer is what kind of collaborative care
palliation
to maintain with treatment is what kind of collaborative care of cancer
control
the study of cancer
oncology
specialist of cancerf
oncologist
a local treatment for cancer -

energy produced by radiation
toxic to cells - disrupts chemical bonds in DNA, cancer cells lose ability to replicate
radiation therapy
____ to radiation varies throughout the cell cycle - useful for cells that are rapidly dividing
cellular sensitivity
the goal of radiation therapy is to
achieve maximum tumor control with minimal damage to normal tissue
external radiation, machine
pt is delivered radiation from a distance

PT NOT RADIOACTIVE
teletherapy
radioactive material placed directly into or adjacent to tumor, ingested in body.

PT IS RADIOACTIVE
brachytherapy
radiation therapy is given pre-op, post-op and intra op

t/f
true
seeds or ribbons implanted directly into or close to tumor


(EX: PROSTATE GLAND)
Sealed Source ( BRACHYTHERAPY)
isotopes given by mouth or IV, I 131 for thyroid cancer
UNsealed source (brachytherapy)
a medication containing radioactive materials is injected into a vein or into a body cavity.
# unsealed internal radiation therapy
radiation side effects can cause
extreme fatigue
extreme fatigue due to radiation is due to what
waste products and the increased metabolism necessary to get rid of it
Name precautions for BRACHYTHERAPY
film badge to detect exposure

6 feet distance / shielding

private room / pregnancy precaut

care with body fluids/linen

DO NOT TOUCH LEAD CONTAINER
What can reduce the size of tumor, followed by radiation/chemo
surgery
risk for recurrance of cancer occurs right after
cured time
blanching, erythema, desquamation, sloughing, hemorrhage, ulcerations of mucous membranes, decreased oral secretions Dry Mouth, hair loss
side effects of Radiation therapy
it is normal to find what in the lungs with radiation therapy
Interstitial Exudate
Pneumonitis
radiation pneumonia
cough
dypsnea
it is normal to find what in the heart after radiation therapy
pericardial effusion, pericarditis
=RADIATION THERAPY=

DO NOT USE HEATING PADS, ICE PACKS, AVOID SUN EXPOSURE
Protect Treatment field
USE NON IRRITATING LOTIONS
MILD SOAPS
PAT SKIN DRY
for which type of cancer is radiation therapy most effective?
Cancers that are LOCALIZED to one tissue or body area
using chemicals as systemic therapy to eliminate or reduce number of malignant cells in primary and secondary tumors is called
chemotherapy
chemotherapy does what to cells?
disrupts cell cycle - damages DNA - interferes with synthesis of enzymes and chemicals needed by the cell
effects cells in process by cellular replication and proliferation including resting phase (any phase)
cell-cycle phase NON SPECIFIC
effect on cells in process of dividing during a specific phase only
Cell cycle phase SPECIFIC
chemotherapy is classified according to
effects of agent on cell and pharmacologic properties
chemotherapy is done pre-op and post-op
true
what has the greatest effect on non tumor cells
systemic (chemicals)
chemotherapy dosing is based on
body surface area (height/weight)
name the SYSTEMIC chemo routes
SYSTEMIC = IV, ORAL, IM
name the REGIONAL chemo routes
REGIONAL =
intracavity
intrathecal
intraventricular
intraarterial
intravesical (into bladder)
WHAT can cause PHLEBITIS and SCLEROSIS?
irritants
what causes damage to the tissue

DO NOT GIVE IV (PERIPHERALLY)
Vesicant
side effects of chemotherapy are a result of
destruction of NORMAL cells
There is NO distinction between normal cells and cancer cells

t/f
true
Anaphalaxis, hypersensitivity reaction, extravasation, anticipatory nausea/vomitiing, cardiac dysrthymias, hemmorhagic cystitis are all what kind of side effects
ACUTE CHEMOTHERAPY SIDE EFFECTS
N/V mucositis, alopecia, skin rash, bone marrow supression, diareeah, constipation, neurotoxicities, fatigue are all what kind of side effects
DELAYED CHEMOTHERAPY SIDE EFFECTS
damage to heart, liver, kidneys, lungs, reproductive dysnfunction are all what kind of side effects
CHRONIC CHEMOTHERAPY SIDE EFFECTS
An increasing TUMOR shows symptoms of
Increased FATIGUE
BONE MARROW SUPRESSION
HEMATOPOIETIC EFFECTS

decreased RBC's ....
anemia
BONE MARROW SUPRESSION
HEMATOPOIETIC EFFECTS

decreased WBCs....
leukopenia
4-10K
BONE MARROW SUPRESSION
HEMATOPOIETIC EFFECTS

decreased neutrophils

THE MOST IMPORTANT!
Neuropenia - MOST IMPORTANT
less than 1000
BONE MARROW SUPRESSION
HEMATOPOIETIC EFFECTS

decreaesd platelets less than 50K
Thrombocytopenia less than 50K
the lowest count of WBC is called
NADIR (peak effect of drug)
BONE MARROW SUPRESSION
HEMATOPOIETIC EFFECTS

decreaesd RBC, WBC, PLATELETS
Pancytopenia
stimulates production, maturation, regulation and activation of the cells of the hematopoeitic system
hematopoietic growth factors
304 LEWIS
what consists of agents that modify the relationship between the host and the tumor by altering biologic response of the host to the tumor cells
biotherapy
biotherapy has direct
anti-tumor effects
THE MAIN SYMPTOM OF NEUTROPENIA IS
FEVER
Biotherapy modulcates _________
host immune system
Biotherapy interferes with the cancer cells ability to
metastasize
WHEN YOUR PT HAS A FEVER DUE TO NEUTROPENIA (DECREASED NEUTROPHILS) YOU MUST
CONTACT MD
manifestations of thrombocytopenia include all but
Leukopenia (deceased wbc)
dizziness, decreased O2, HYPOTENSION are symtpoms of
anemia
granulocytes colony, stimulates neutrophils

stimulating factor G -CSF
NEUPOGEN/neulasta
erthrythropoietin - stimulates RBC
EPOGEN/procrit
interleukin 11 - stimulates WBC
NEUMEGA/interleukin
cancer can be treated with replacing bone marrow through a donor, and using chemo to kill the bad bone marrow, this process is by
stem cell transplants
peripheral blood stem cells require _______- which takes the blood out, removes STEM CELLS, then replaces the blood
aphoresis
Biotherapy coorelates with what kind of symptoms
FLU - LIKE
Headache, fever, chills, myalgias, fatigue, malaise, weakness, photosensistivity, anorexia, nausea
name other symptoms of biotherapy
tachycardia
orthostatic hypotension
confusion, memory loss, insomnia
The RN action for Biologic therapy is to
EDUCATE
Treat FLU symtpoms
genetic material introduced into patients cells to fight disease
gene therapy
gene therapy enhances the cells ability to
fight cancer
what does gene therapy target?
gene therapy targets cancer cells to destroy or prevent growth
PETACHIAE
ECCHMOSIS
GINGIVAL BLEEDING
are all manifestations of
thrombocytopenia (decreased platelet count)
Action before entering chemo patient room is to
wear protective gown and respiratory mask when completing treatments.
KNOW BONE MARROW SUPRESSION TERMS
ANEMIA, LEUKOPENIA, NEUTROPENIA, THROMBOCYTOPENIA,PANYCTOPENIA