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22 Cards in this Set
- Front
- Back
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IL 1
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Source: 12. Monocytes, macrophages Fxn: Stimulates T cell proliferation & IL2 produciton
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IL 2
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Source: 13. Macrophages, T & NK cells Fxn: Stim prolif of B, T & NK cell
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IL 3
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Source: 14. T cells Fxn: GF of tissue mast cells & hematopoietic stem cells
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IL 4
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Source: 15. T cells Fxn: ↑ growth of B & T cells/ ↑ HLA II Ags
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IL 5
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Source: 16. T cells Fxn: Maturation of B >>> plasma cell
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IL 6
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Source: 17. T cells, monocytes Fxn: Maturation of B & T cell/ (-) fibroblasts
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IFN α
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Source: 18. B cells, macrophages Fxn: Antiviral activity
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IFN β
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Source: 19. Fibroblasts Fxn: Antiviral activity
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IFN gamma
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Source: 20. T & NK cells Fxn: Antiviral activity, (+) macrophages, ↑ HLA II Ags
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TNF α
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Source: 21. Macrophages, T & NK cells Fxn: T cell prolif, IL 2 prod, cytotoxicity
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TNF β
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Source: 22. T cells Fxn: T cell prolif, IL 2 prod, cytotoxicity
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VHL
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3p Von Hippel Lindau, Renal Cell CA
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APC
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5p Familial adenomatous polyposis, Colon CA
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WT-1
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11p Wilm’s tumor
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Rb
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13q Retinoblastoma, Osteosarcoma
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BRCA-2
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13q Breast CA
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p53
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17p Most human Cas
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NF-1
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17q Neurofibromatosis type 1
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BRCA-1
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17q Breast CA, Ovarian CA
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DCC
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18q Colon & Stomach CA
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DPC
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18q Pancreatic CA
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NF-2
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22q Neurofibromatosis type 2 = bilateral acoustic neuroma
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