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7 Cards in this Set
- Front
- Back
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Characteristics of Staph (8)
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*Means bunches of grapes
*Gram positive Cocci in "grape like" clusters *Found in normal flora of skin, mucous membranes, feces, GI tract, Mouth *32 species/subspecies *Facultative anerobe *Tolerates High Salt Conditions *Nonmotile (can't move) *Nonsporeforming |
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Staph Aureus (Virulence Factors) Chaz loves every loose P he hits
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Most important Staph. 'Golden'
Virulence Factors: *Coagulase - Protein that clots plasma and can prevent phagocytosis *Leukocidin - exotoxin that kills neutrophils *Entertoxins - (responsible for symptoms) Nausea, vomiting, *Lipases - Hydrolyzes lipids and allows spreading *Hyaluronidase - dissolves intercellular matrix of tissues *Protein A - prevents phagocytosis *Hemolysins - Alpha and Delta kill RBCs, Monocytes, platlets |
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Staph Aurues Conditions
(Some Fine...) |
1. Skin Infections (pimples, impetigo, pyoderma)
2. Food Poisoning (Milk products, usually from hands of the handlers) 3. Toxic Shock Syndrome 4. Pneumonia 5. Osteomyelitis - (inflammation of bone) 6. Gastroenteritis (food poisoning) |
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Staph epidermidis (EPI)
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Low Virulence
Inhabits skin of most people Diseases *Endocarditis *Prosthetic infections *IV site infections - sepsis |
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Staph Saprophyticus
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UTI, Sexually active women. Affinity for epithelium of urethra or bladder
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Coagulase Indentifcation test
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If positive for coagulase, staph aureus is present
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MRSA
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Methicillin resistant staph aureus.
Vancomycin is drug of choice Penicillin --> Methicillin --> Vancomycin ---> Dead |
