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11 Cards in this Set

  • Front
  • Back
What is the most common immunodeficiency?
selective IgA deficiency
______________ measures the light that is scattered at a particular angle from the incident beam as it passes through a suspension. The amount of light scattered is an index of the suspension’s concentration. The light scatter changes proportionally with antigen-antibody complex formation.
nephelometry
Which serology test has the benefit of allowing multiple tests on a small sample by using color-coded polystyrene microspheres
Fluorescent Microsphere-based Immunoassay
What lab test is commonly used as a confirmatory test for HIV?
Western Blot
What are the 4 clinical settings for immune-mediated hemolysis?
Transfusion reaction, Hemolytic disease of newborn, drug-induced hemolysis, autoimmune hemolytic anemia
What serum antibody/rbc antigen would present in a blood type A patient? type B? type AB? type O?
Type A: Anti-B Ab(antibody), A Ag(antigen); Type B: Anti-A Ab, B Ag; Type AB: no Ab, A and B Ag; Type O: Anti-A and Anti-B Ab, H antigen
What blood type is the 'universal donor'? What blood type is the 'universal recipient'?
Universal donor: Type O (there are no anti-bodies acting against H antigen); Universal recipient: Type AB (because it produces neither Anti-A nor Anti-B Ab's, the patient can receive blood of all types)
Which antigen contributes to hemolytic disease of newborn?
D (Rhesus blood group)
are most of the population Rh+ or -?
Rh+
Would the first Rh- baby of a Rh+ mother have hemolytic disease? Why or why not?
No. This would not occur until subsequent pregnancies because the mother had not yet developed memory cells in the first pregnancy. During the second and subsequent pregnancies, IgG against D antigen would reach the fetal circulation.
What is used to prevent hemolytic disease of newborn?
Anti-Rh prophylaxis administered to Rh- mothers