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11 Cards in this Set
- Front
- Back
What is the most common immunodeficiency?
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selective IgA deficiency
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______________ measures the light that is scattered at a particular angle from the incident beam as it passes through a suspension. The amount of light scattered is an index of the suspension’s concentration. The light scatter changes proportionally with antigen-antibody complex formation.
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nephelometry
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Which serology test has the benefit of allowing multiple tests on a small sample by using color-coded polystyrene microspheres
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Fluorescent Microsphere-based Immunoassay
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What lab test is commonly used as a confirmatory test for HIV?
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Western Blot
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What are the 4 clinical settings for immune-mediated hemolysis?
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Transfusion reaction, Hemolytic disease of newborn, drug-induced hemolysis, autoimmune hemolytic anemia
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What serum antibody/rbc antigen would present in a blood type A patient? type B? type AB? type O?
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Type A: Anti-B Ab(antibody), A Ag(antigen); Type B: Anti-A Ab, B Ag; Type AB: no Ab, A and B Ag; Type O: Anti-A and Anti-B Ab, H antigen
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What blood type is the 'universal donor'? What blood type is the 'universal recipient'?
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Universal donor: Type O (there are no anti-bodies acting against H antigen); Universal recipient: Type AB (because it produces neither Anti-A nor Anti-B Ab's, the patient can receive blood of all types)
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Which antigen contributes to hemolytic disease of newborn?
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D (Rhesus blood group)
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are most of the population Rh+ or -?
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Rh+
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Would the first Rh- baby of a Rh+ mother have hemolytic disease? Why or why not?
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No. This would not occur until subsequent pregnancies because the mother had not yet developed memory cells in the first pregnancy. During the second and subsequent pregnancies, IgG against D antigen would reach the fetal circulation.
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What is used to prevent hemolytic disease of newborn?
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Anti-Rh prophylaxis administered to Rh- mothers
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