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5 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Pernicious Anemia B12 deficiency
Causes |
*Strict vegan diet
*Autoimmune disease-no intrinsic factor *Gastric surgery *Severe Chron’s disease |
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Pernicious Anemia B12 deficiency
Signs and Symptoms |
*Changes in mucosal cells
*Anorexia *Diarrhea *Pt can be pale *Mildly icteric |
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Pernicious Anemia B12 deficiency
Classic Lab findings |
*Increased MCV (Macrocytic)
*Anisocytosis *Poikilocytosis *In severe cases WBC and platelet levels decrease & pancytopenia occurs *Bone marrow morphology is abnormal *Increase LDH *Modest increase indirect bilirubin *Decreased serum B12 |
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Pernicious Anemia B12 deficiency
Complications |
Peripheral Neuropathy
*Lifelong disorder |
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Pernicious Anemia B12 deficiency
Typical Tx |
*Parenteral IM injections
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