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6 Cards in this Set

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Hereditary Spherocytes
Classic Lab findings;*Reticulocytosis
*Spherocytes
*Small cells with loss of central pallor/*Microcytosis/
Hereditary Spherocytes
Causes
*Hereditary disorder of RBC membrane leading to chronic hemolytic anemia and sphere shaped RBC’s
.
Hereditary Spherocytes
Signs and Symptoms
*Autosomal dominant
*Shortened RBC survival
*Jaundice
*Pigment gallstones
*May have icterus and palpable spleen
.
Hereditary Spherocytes
Classic Lab findings
*Reticulocytosis
*Spherocytes
*Small cells with loss of central pallor
*Microcytosis
*Increased MCHC
.
Hereditary Spherocytes
Complications
*Splenomegaly
.
Hereditary Spherocytes
Typical Tx
*PO Folic acid
*Splenectomy
(may not be necessary in mild cases diagnosed in adulthood)
.