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5 Cards in this Set

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G6PD deficiency
Causes
*X-linked recessive
*Enzyme defect which cause episodic hemolytic anemia due to inability of RBC to deal with oxidative stresses
.
G6PD deficiency
Signs and Symptoms
*Generally African-americans
*Pts are usually healthy
*Occur under oxidative stress from infection
drug exposure
.
G6PD deficiency
Classic Lab findings
*Between episodes blood is Normal
*During episode reticulocytosis and increased serum indirect bilirubin
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G6PD deficiency
Complications
*Severe cases may produce chronic hemolytic anemia
.
G6PD deficiency
Typical Tx
*No treatment except avoidance of known oxidant drugs
.