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9 Cards in this Set
- Front
- Back
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___?___ therapy remains the most effective therapy for parkinsons
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levodopa therapy
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L-Dopa is converted to ___?___ by ___?___ in the brain
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dopamine
LAAAD |
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parkinsons results as a __?__ of dopamine and an ___?___ of ACh
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deficiency
excess |
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Carbidopa is given in order to block peripheral ___?___
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decarboxylase activity
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Carbidopa does what to L-DOPA?
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increases the amount of L-DOPA that can get to the brain by inhibiting it metabolism in the peripheries
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These agents prolong the action of levodopa by inhibiting the methylation to 3-methoxy-DOPA in the periphery
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COMT inhibitors (Catechol-O-Methyl Transferase)
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___?___ is a dopamine release modulator
it releases dopamine from ___?___ sites |
amantadine
intraneuronal storage |
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Dopamine receptor agonists which are ergot alkaloid derivatives act at the __?__ receptors
These are used in combination with ? |
D2 receptors
Levodopa |
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Non-Ergot dopamine receptor agonists act as full agonists at the ? receptors
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D2 and D3 receptors
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