Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
|
most reactive AA? spontaneously reacts
|
mechlorethamine
|
|
|
dec. uptake by choline transport (resist)
|
mechlorethamine
|
|
|
give N-acetylcysteine to help bladder tox?
|
cyclophosphamide
|
|
|
mechlorethamine analogs?
|
melphalan, chlorambucil
|
|
|
palliative Tx?
|
thiotepa
|
|
|
intravesicle injection to bladder?
|
thiotepa
|
|
|
for Hodgkin's?
|
mechlorethamine, vincristine, L/C
|
|
|
only monofunctional?
|
L/C
|
|
|
for bone marrow tranplants?
|
busulfan
|
|
|
spontaneously reacts with water & DNA bases & proteins?
|
L/C
|
|
|
forms x-links and monoadducts?
|
cisplatin
|
|
|
what sort of ion transfers a alkyl group to a macromolecule?
|
carbonium ion (AA)
|
|
|
what do AA attack?
|
nucleophils (with (-) charges)
|
|
|
avoid aluminum equipment?
|
cisplatin
|
|
|
most reactive AA? spontaneously reacts
|
mechlorethamine
|
|
|
dec. uptake by choline transport (resist)
|
mechlorethamine
|
|
|
give N-acetylcysteine to help bladder tox?
|
cyclophosphamide
|
|
|
mechlorethamine analogs?
|
melphalan, chlorambucil
|
|
|
palliative Tx?
|
thiotepa
|
|
|
intravesicle injection to bladder?
|
thiotepa
|
|
|
for Hodgkin's?
|
mechlorethamine, vincristine, L/C
|
|
|
only monofunctional?
|
L/C
|
|
|
for bone marrow tranplants?
|
busulfan
|
|
|
spontaneously reacts with water & DNA bases & proteins?
|
L/C
|
|
|
forms x-links and monoadducts?
|
cisplatin
|
|
|
resist: inc. GSH, inc. DNA repair enzymes
|
cisplatin
|
|
|
what sort of ion transfers a alkyl group to a macromolecule?
|
carbonium ion (AA)
|
|
|
what do AA attack?
|
nucleophils (with (-) charges)
|
|
|
avoid aluminum equipment?
|
cisplatin
|
