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14 Cards in this Set
- Front
- Back
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Which drugs bind to GABAa receptors at the alpha position? (3)
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diazepam
clonazepam triazolam |
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Which drugs bind to GABAa receptors at the omega position? (3)
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zolpidem
zaleplon eszopiclone |
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Which drug is a melatonin receptor agonist?
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ramelteon
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Which three (3) benzodiazepines cause amnesia?
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zolpidem
zaleplon eszopiclone |
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Eszopiclone
(side effects - 4) |
hallucinations, anxiety, amnesia, unpleasant taste
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Ramelteon
(side effects - 2) |
depression, worsened insomnia
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What is the bioavailability of ramelteon?
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1.8 %
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What does the alpha1 subtype cause?
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sedation/hypnosis
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Which subtypes are responsible for benzodiazepine anxiolytic effects?
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alpha2, alpha5
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Which subtypes are responsible for benzodiazepine anticonvulsant effects?
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alpha1, alpha2, alpha3
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What is the selectivity of diazepam?
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nonselective
alpha1 = alpha2 = alpha3 = alpha5 |
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What is the selectivity of clonazepam?
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anticonvulsant
alpha1 = alpha2 = alpha 3 |
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What is the selectivity of triazolam?
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anxiolytic
alpha2 = alpha 5 > alpha1 > alpha3 |
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What is the selectivity of zolpidem?
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sedative/hypnotic
alpha1 > alpha2 > alpha3 >>> alpha5 |
