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64 Cards in this Set

  • Front
  • Back
Staphylococci: gram positive or gram negative?
gram positive
Staphylococci: grow in what type colonies?
clusters
Staphylococci: do they form pus?
yes (pyogenic)
Staphylococci: do they form endospores?
no. but they can survive for long periods on dry inanimate objects.
Staphylococci: general discription.
grow on 10% salt, nonmotile, facultative anaerobe, has a capsule. Catalase positive, oxidase negative.
Staphylococci: describe colonies.
large, round, mucoid, golden for S. aureus
Staphylococci: optimum temp?
30-37 C
Staphylococci: susceptible to lysis by...
lysozyme
S. aureus specific features
ferments mannitol and is coagulase positive.
Staphylococci: three main species
S. aureus, S. epidermidis, and S. saprophyticus
S. aureus is bad because
produces so many enzymes, allowing it to cause a variety of diseases.
S. aureus causes (13 things)
furuncles, carbuncles, wound infection, cellulitis, bacteremia with metastatic abcesses, endocarditis, pulmonary infections, arthritis, osteomyelitis, GU tract infections, toxic shock syndrome (TSS), scalded skin syndrome (SSS), and food poisoning gastroenteritis.
S. aureus is able to withstand phagocytosis by neutrophilis because it produces
exotoxins and enzymes making it very hard to remove from the human environment.
S. saprophyticus causes
urinary tract infections
S. aureus is resistant to ___ but sensative to ___.
penicillin; oxacillian.
S. aureus toxin
enterotoxin A
S. epidermidis found
on the skin.
Percentage of humans that house S. aureus, where, and percentage that turn into colonies.
30%, in the nares, and 90%.
Protein needed for colonizing S. aureus
fibronectin binding protein (FNBP)
Fibronectin is
extracellular matrix protein exposed in wounds
S. aureus has receptors for ___ and ___, important components of connective tissue, bones, and joints.
Collagen IV and sialoprotein.
S. aureus also has receptors for ___, a key protein present in basement membrane of epithelial and endothelial linings.
laminin
Staph spreads via...
...person to person contact.
... aerosols from pneumonia patients.
...
People high on the list for staph carriers include...
physicians, diabetics, dialysis patients, and IV drug abusers.
Nosocomial infections are...
... infections that are a result of treatment in a hospital or a healthcare service unit. Infections are considered nosocomial if they first appear 48 hours or more after hospital admission or within 30 days after discharge.
Iatrigenic (definition)..
Of or relating to illness caused by medical examination or treatment.
Typical ENTRY of Staph
Since they are on skin, the typical entry of staph in to the body is via laceration, insect bites, burns, or surgical intervention. Massive quantities can enter through poor hygiene.
SPREAD and MULTIPLY of Staph
typically not trouble, but depends on number of organisms, site, body response speed.
DAMAGE of Staph:
local...
abscess on surface...
subcutaneous...
...boil
...furuncle (one folical), carbubcle (multi folical)
...cellulitis
DAMAGE caused specificially by S. aureus and how it is caused...
Chronic Granulomatous Disease - hereditary in children - neutrophils do not produce enough H2O2 to set off the oxidative killing pathway.
organisms with capsules
Some-Streptococcus pnumoniae
Killers-Klebsiella pnumoniae
Have-Haemophilis influenzae
Pretty-Pseudomonas aeruginosa
Nice-Neisseria meningitidis
Capsules-Cryptococcus neoformans

others
Staphylococcus. aureus
Bacteroides fragilis
Bordetella bronchiseptica
Fusobacterium nucleatum
Bacillus anthracis
almost all pathogenic coccus are
either staph or strep
BSE
bovine spongiform encephalopathy
MMR
measles, mumps, and rubella
BSA
bovine serum albumin
OR
broad spectrum antibiotic
DIC
disseminated intravascular coagulation
ARF
acute rheumatic fever
SSS
scalded skin syndrome
SOD
superoxide dismutase
PID
pelvic inflammatory disease
CMV
cytomegalovirus
NAD
nicotinamide adenine dinucleotide
EIEC
Enteroinvasive Escherichia coli
HUS
hemolytic-uremic syndrome
LPS
lipopolysaccharide
LOS
lipooligosaccharide (shorter LPS)
EHEC
enterohemorrhagic Escherichia coli
VRE
vancomycin-resistant enterococcus
DPT
diphtheria-pertussis-tetanus vaccine
CDC
Centers for Disease Control and Prevention
HIV
human immunodifficiency virus
AIDS
acquired immunodificiency syndrome
MRSA
methicillin resistant Staphylococcus aureus
VRSA
vancomycin-resistant Staphylococcus aureus
INH
isoniazid
GAS
Group-A Strep
OPV
Oral polio vaccine (Sabin - no booster needed)
IPV
Inactivated polio vaccine (Salk - needs booster)
DNA
deoxyribonucleic acid
EPEC
Enteropathogenic Escherichia coli
EAggEC
Enteroaggregative Escherichia coli
Sporosarcina
gram +
rod
endospore forming

S. pasteurii
Sporolactobacillus
gram +
rod
anaerobic
endospore forming
motile
lactic acid bacteria
CAT -

S. dextrus
Endospore forming:
Clostridium
Sporosarcina
Bacillus
Sporolactobacillus
Thermoactinomyces