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80 Cards in this Set
- Front
- Back
acquired immunity
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production of antibodies and lymphocytes after exposure to an antigen
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acquired immunodeficiency syndrome (AIDS)
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group of clinical signs and symptoms associated with suppression of the immune system and marked by opportunistic infections, secondary neoplasms and neurologic problems
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adenoids
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mass of lymphatic tissue in the nasopharynx
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allergen
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substance capable of causing a specific hypersensitivity reaction in the body; a type of antigen
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allergy
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abnormal hypersensitivity acquired by exposure to an antigen
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anaphylaxis
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exaggerated or unusual hypersensitivity to foreign protein or other substance
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antibody
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protein produced by B cell lymphocytes to destroy antigens
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antigen
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Any of various substances, including toxins, bacteria, and the cells of transplanted organs, that when introduced into the body stimulate the production of antibodies
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asplenia
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absence of a spleen. The condition may be congenital or result from surgical removal.
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atopy
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hypersensitive or allergic state involving an inherited predisposition. From the Greek work atopia, which means strangeness
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autoimmune disease
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A diseases in which the body's immune system, responsible for fighting off foreign invaders such as bacteria and viruses, begins to attack and damage a part of the body as if it were foreign.
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axillary nodes
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lymph nodes in the armpit (underarm)
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B cell (B lymphocyte)
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lymphocyte that originates in the bone marrow and transforms into plasma cell to secrete antibodies. The B refers to the bursa of Fabricius, an organ in birds in which B cell differentiation and growth were first noted to occur
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CD4+ cells
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helper T cells that carry the CD4 protein antigen on their surface. HIV binds to CD4 and infects and kills T cells bearing this protein. AIDS patients have an inadequate number of CD4+ cells
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cervical nodes
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lymph nodes in the neck region
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complement system
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proteins in the blood that help antibodies and T cells kill their target
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cytokines
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proteins that aid and regulate the immune response
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cytotoxic T cell
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T lymphocyte that directly kills foreign cells (CD8+ cell or T8 cell)
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dendritic cell
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specialized macrophage that digests foreign cells and helps B and T cells to mark antigens for destruction
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ELISA
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screening test to detect anti-HIV antibodies in the bloodstream
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helper T cell
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lymphocyte tha aids B cells and cytotoxic T cells in recognizing antigens and stimulating antibody production; also called CD4+ cell or T4 cell
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Hodgkin disease
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malignant tumor of lymphoid tissue in spleen and lymph nodes; Reed-Sternberg cell often is found on microscopic analysis
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human immunodeficiency virus (HIV)
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virus that causes AIDS
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hypersensitivity
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An excessive reaction, local or systemic, or inappropriate immune response to an antigen
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hypersplenism
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syndrome marked by splenomegaly and often associated with blood cell destruction, anemia, leukopenia and thrombocytopenia
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immunity
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body's ability to resist foreign organisms and toxins.
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immunoelectrophoresis
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test that separates immunoglobulins
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immunoglobulins
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antibodies such as IgA, IgE, IgC, IgM, and IgD that are secreted by plasma cells in response to the presence of an antigen
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immunotheraphy
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use of immune cells, antibodies, or vaccines to treat or prevent disease
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immunosuppression
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Suppression of the immune response, as by drugs or radiation, in order to prevent the rejection of grafts or transplants or control autoimmune diseases
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inguinal nodes
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lymph nodes in the groin region
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interferons
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proteins secreted by T cells to aid and regulate the immune response
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interleukins
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proteins that stimulate the growth of B and T lymphocytes
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interstitial fluid
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fluid in the spaces between cells. this fluid becomes lymph when it enters lymph capillaries
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Kaposi sarcoma
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malignant lesion associated with AIDS; arises from the lining of capillaries and appears as red, purple, brown, or black skin nodules
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lymph
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thin, watery fluid found within lymphatic vessels and collected from tissues throughout the body
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lymphadenitis
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inflammation of one or more lymph nodes
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lymphadenopathy
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disease of the lymph nodes
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lymph capillaries
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tiniest lymphatic vessels
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lymphedema
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interstitial fluid collects with in the spaces between cells as a result of obstruction of lymphatic vessels and nodes
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lymph nodes
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a collection of stationary solid lymphatic tissue along lymph vessels
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lymphocytes
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Small white blood cells that bear the major responsibility for carrying out the activities of the immune system; they number about 1 trillion.
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lymphocytosis
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A condition marked by an abnormal increase in the number of lymphocytes in the bloodstream, usually resulting from infection or inflammation.
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lymphocytopenia
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condition marked by an abnormally low level of lymphocytes in the blood
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lymphoid organs
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lymph nodes, spleen and thymus gland
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lymphoma
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malignant tumor of lymph nodes and lymph tissue
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lymphopoiesis
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The formation of lymphocytes.
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lymph vessel
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carrier of lymph throughout the body; lymphatic vessels empty lymph into veins in the upper part of the chest
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macrophage
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large phagocyte found in lymph nodes and other tissues of the body
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mediastinal nodes
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lymph nodes in the area between the lungs in the thoracic (chest) cavity
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monoclonal antibody
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produced in a laboratory to attack antigens and to destroy cells.
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multiple myeloma
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malignant tumor of bone marrow cells
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natural immunity
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protection that an individual inherits to fight infection
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non-hodgkin lymphomas
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group of malignant tumors involving lymphoid tissue.
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opportunistic infections
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he secondary infections that occur in patients whose immune systems are compromised, such as in AIDS or after chemotherapy.
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plasma cell
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lymphoctye that produces and secretes antibodies. It originates from B lymphocytes
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protease inhibitors
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drug that treats AIDS by blocking the production of protease, a proteolytic enzyme that helps create new vital pieces for HIV
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reverse transcriptase inhibitors
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drug that treats AIDS by blocking reverse transcriptase, an enzyme needed to copies of HIV
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right lymphatic duct
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large lymphatic vessel in the chest that receives lymph from the upper right part of the body
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severe combined immunodeficiency disease (SID)
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infants are born with deficiency B cells and T cells, resulting in the lack of immunity
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spleen
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organ near the stomach that produces, stores, and eliminates blood cells
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splenectomy
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Surgical removal of the spleen
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splenomegaly
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enlargement of the spleen
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suppressor T cell
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lymphocyte that inhibits the activity of B and T lymphocytes. Also called a Treg (regulatory T cell)
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T cell ( T lymphocyte)
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originates in the bone marrow but matures in the thymus gland; it acts directly on antigens to destroy them or produce chemicals such as interferons and interlukins that are toxic to antigens
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thoracic duct
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large lymphatic vessel in the chest that receives lymph from below the diaphragm and from the left side of the body above the diaphragm; it empties the lymph into veins in the upper chest
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thymectomy
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Surgical removal of the thymus gland.
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thymoma
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malignant tumor of the thymus gland
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thymus gland
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organ in the mediastinum that conditions T lymphocytes to react to foreign cells and aids in the immune response
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tonsils
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mass of lymphatic tissue in the back of the oropharynx
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toxic
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poison
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toxin
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poison; a protein produced by a certain bacteria, animals and plants
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vaccination
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exposure of an individual to a foreign protein that provokes an immune response.
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vaccine
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weaken or killed microorganisms, toxins, or other proteins given to induce immunity to infection or disease
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viral load test
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measurement of the amount of AIDS virus (HIV) in the bloodstream
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wasting syndrome
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marked by weight loss and decrease in muscular strength, appetite, and mental activity, also may occur with AIDS
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Western blot
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A technique developed in 1979 that is used to confirm ELISA results. HIV antigen is purified by electrophoresis and attached by blotting to a nylon or nitrocellulose filter.
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tolerance
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ability of T lymphocytes to recognize and accept the body's own antigens as "self" or friendly
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cell-mediated immunity
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T cells (cytotoxic , helper and suppressor) that respond to antigens and destroy them: a type of adaptive immunity
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humoral immunity
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B cells produce antibodies after exposure to specific antigens; type of adaptive immunity
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