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96 Cards in this Set

  • Front
  • Back
What is cancer?
caner is characterized by abnormal unrelated cell proliferation. Invade normal tissue and compete with normal cells for oxygen nutrients and space.
What is neoplasms?
Abnormal tissue or tumors
"oma" indicate a tumor
What is the 4 main classification of tumors?
Carcinomas-epithelial cells
Lymphomas-organs that fight infection
Leukemias-organs that form blood
Sarcomas-connective tissue (bone and muscle)
What are the 3 classifaction of tumor growths?
Benign, Malignant, metastasis
what is TNM?
T - sizeof tumor
N- involvement of lymph nodes
M - metastasis
What is stage I of tumors?
malignant cells are confined to the tissue of orgin
Once cancer has metastasized is it difficult to treat?
yes it is difficult to treat and at times less likely to be curative
What is thestage II of tumors?
spread to local area usually the lymph nodes
What is stage III of tumors?
larger tumor or spread to surrounding tissues or both
What is the stage IV of tumor?
metastasized to distant body parts
what are the clasification of tumors/
anatomic site
stage
cell appearance and differentation
Carcinomas of the testicles, pancreas, and liver is what type of lab?
Alpha-fetoprotein
Increased with breast, pancreas, liver, kidney and colon cancer. (Maybe elevated for no reason) is what type of lab?
Carinoembryonic antigen(CEA)
Prostate cancer, slightly elevated in benign prostate hyperplasia is what type of lab?
Prostate - specific antigen(PSA)
What type of lab testing is used for meteastic breast cancer?
CA 15-3
what type of lab is used for gastrointestinal and pancreatic cancers?
CA 19-9
what type of lab is used for ovarian cancer?
CA 125
What type of x-ray will give you a 3 dimmensional view of tissue to determine tumor density, size and location?
CT
What type of x-ray is used for tissue is being obeserved for changes using radioactive isotope?
Nuclear imaging
What type of x-ray uses cross-sectional view of tissue to look at increased concentration of isotopes in malignant cells & differentiates between benign & malignant cells?
PET
What type of x-ray is used for monoclonal antibodies labeled with isotopes are injected intravenously & accumulate at the tumor site which makes tumor able to be visualized.
Radioimmunoconjugates
What uses high frequent sound waves to determine if the tumor is solid of fluid filled?
Ultrasound
What type of x-ray used to look at differences in the densities of body tissues and used for bone and gastric cancers?
Fluoroscopy
what are the warning signs of tumors being present?
change in bowels
sores that do not heal
unusual bleeding or discharge
thickening or lump in breast or other body parts
indigestion or difficulty swallowing
a recent change in a wart or mole
a nagging cough or hoarseness
What is it called when immediate examination of the cells tumor removed the specimen is quickly frozen then sliced into thin sheets and observed?
frozen section
Waht type of treatment is done to remove a tumor that has not invaded surrounding tissues and is confined?
Surgey
Waht is it called when the entire tumor cannot be removed?
Debulking
What is it called when the tumor and a small amount of surrounding healthy tissues are removed?
local excision
Removes tumors, lymph nodes any involved adjacent structures and surrounding tissue that poses a risk for metastasis?
wide or radial excision
done with a local recurrance of cancer, more extensive than previous surgery
salvage surgery
client is at high risk for developing cancer, usually done for breast or reproductive cancers
prophylactic
relieve uncomfortable symptoms or prolong life and not a cure
palliative
high-energy ionizing radiation used to destroy cancer cells by disrupting cell function, division& alteration of DNA molecules and cell death occurs immediately or no more repruduction can occur
radiation therapy
malignant cells are more sensitive to what treatment?
external radiation causes damage to the cell's DNA impairing reproduction
A patient getting external radiation what should the nurse keep in mind or tell the patient?
it will be marked with a marker or tattoo and do not wash the markings and do not apply any lotions ect. to the radiation area.
Internal radiation
brachytherapy, radioactive source that is implanted or placed on the tumor implanted inside the patient's body & poses a threat to others
what type of radiation is a sealed sorce that is inserted into the body in a sealed container directly into the tumor body & can be held in place with an applicator?
internal radiation
What are the precautions that the nurse needs to do & keep in mind for a patient that has internal radiation?
Private room, lead llined
sign on the door
no children or preg. women
limit time in the room
use lead aprons, monitoring devices
30 min. per shift
monitor for accidental dislodge sources
What are some precautions that the nurse needs to do or keep in mind with a patient that has unsealed source of internal radiation?
wear gloves
body fluids require special considerations because radiation is excreted through the urin, saliva, sweat glands, and feces
use seperate eating utensils
wash clothes separately
drink plenty of fluids to flush system
What type of therapy uses antineoplastic agents to treat cancer cells?
chemotherapy
Chemotherapy can be used for what ?
cure cancer, prevention of metastasis,slow growth of tumor, destroy tumor cells or relieve symptoms
How can chemotherapy be given to a patient?
Given by orally, IV, IM, intraperitoneally, intrapleurally, topically, intrathecally or directly into a cavity
alkylating drugs and mitotic inhibitors does what?(cytotoxic)
interfere with the process of cell division
antineoplastic antibiotics and antimetabolites does what?(cytotoxic)
interefer with DNA & RNA
what is used in treating cancers that uses hormones as growth factors?
hormones (cytotoxic)
what type of stem cell transplant come from the client either from the bone marrow or circulating blood.
autologous stem cell
what type of stem cell transplant comes from a dodor whose tissue type matches the client?
allogeneic stem cell
what type of stem cell comes an identical twin with identical tissue type?
syngeneic stem cell
what type of therapy uses biologic response modifiers to stimulate the body's natural immune system to restrict and destroy cancer cells?
immunotherapy (1)
what manipulates the natural immune response by restoring, stimulating or augmenting the natural defenses?
immunotherapy (2)
Antigen injected into client in hopes to stimulate an immune response to destroy malignant cells
Nonspecific immunotherapy
Tumor cells are injected into mice to form antibodies

Antibodies are removed from the spleen and cultured with more cancer cells to form more antibodies which are injected into a client to destroy tumor cells (after purification)
Monoclonal antibody immunotherapy
4 Types of Cytokines is what?
1 Interferons
2 Interleukins
3 Hematopoietic growth factors (colony stimulating factors)
4 Tumor necrosis factor
What type of therapy uses
temps > 41.5 C (106.7 F) to destroy tumor cells?
hyperthermia
What does hyperthermia do to the cell membrane?
Alters cell membrane permeability so that uptake of chemo and immunotherapeutic agents are increased
Radio waves, US, microwaves, hot water baths used for what type of therapy?
Hyperthermia
what does the client experience during Hyperthermia therapy?
Clients may experience local burns, tissue damage, electrolyte imbalances and neuropathies
what type of therapy uses Photoactive drug injected into client (porfimer/ Photofrin)
Photodynamic Therapy
what is a patient teaching using the Photodynamic Therapy?
Clients must stay protected from sunlight and bright indoor lights for 30 days

Sunburns can occur if noncompliant
What is the process that rids the body of cells that are no longer needed or defective in some way?
Apoptosis
Lung Cancer is it the no. one cause of cancer deaths?
yes
What type of cell is
Slow growing
Arise from the bronchi and bronchioles leading to obstruction
Mets to the thorax and small bowel
25 to 35% of all lung tumors?
Epidermold or Squamous Cell
What type of cell
Arise in the peripheral bronchi

No well-defined growth patterns

Usually diagnosed as a bulky tumor mass

Mets early to the CNS

5 to 20% of all lung tumors?
Large Cell or Undifferentiated
Arise from the mucus glands

Patchy growth throughout lung fields

Lead to malignant pleural effusion

25 to 35% of lung tumors
Adenocarsinoma
Most malignant form of lung cancer

Arises from the bronchi.

Hypersecretes antidiuretic hormone

Mets to the mediastinum, liver, bone, bone marrow, CNS, adrenal glands, pancreas, and other endocrine organs
Small Cell Carcinoma or Oat Cell
Any malignant blood disorder in which the leukocytes (WBCs), usually in an immature form, proliferate (grow) unregulated.

Often accompanied by a decrease in erythrocytes (RBCs) and platelets.
Leukemia
Onset is usually younger than 5, rarely over 15.

Increased lymphocytes, decrease RBC’s and platelets
Acute lymphocytic leukemia
Onset is older that 40

Most common type in adults

Increased lymphocytes, normal or low RBC’s and platelets
Chronic lymphocytic leukemia
Decrease in myeloid formed cells (monocytes, granulocytes, RBC’s and platelets)

Occurs in all age ranges
Acute myelogenous leukemia
Same as AML but greater number of normal cells.

Onset is older than 20, increasing incidence with age.

Genetic link
Chronic myelogenous leukemia
Malignancy involving the plasma cells or B-lymphocyte cells in the bone marrow.

Prognosis is poor with estimated survival rate of 1 to 5 years.
Multiple Myeloma
Cancer that affect the lymphatic system

Two types

Hodgkin’s

Non-Hodgkin’s
Lymphoma
Age of onset is 15 – 40 and then older than 55.

Has Reed-Sternberg cells

Orderly growth

More curable
Hodgkins
Non-Hodgkins
Thirty subtypes

Peaks after 50

No Reed-Sternberg cells

B and T cell origins

Mets common

Less curable
Brain tumors
Benign tumors can be fatal because of increased ICP and damage to surrounding tissues.
Gliomas are the most common
Many develop from benign adenomas what is it called?
Cancer of the GI tract
what type of cancer is palliative therapy?
Cancer of the Liver
If a patient has pain jaundice, weight loss, nausea and vomiting and diarrhea what is the cancer that the patient might have?
cancer in the head of the pancreas?
If the patient c/o of GI bleed or back pain where are the tumors might the patient have?

Quickly spreads to duodenum, stomach, spleen and left adrenal gland.
tumors in the center and tail
If a patient comes in with s/s
anemia, weakness and weight loss. Gross hematuria and flank pain are late signs.
what might the patient have?
Cancer of the kidneys
Signs and symptoms include pathological break, limp or abnormal gait what might this be if your patient c/o of these s/s?
bone cancer
Endometrial cells that migrate out of the uterus and attach to other organs in the pelvic cavity.

Builds and bleeds like the tissue within the uterus, causing pain and local inflammation.

Considered benign uterine growth
Endometriosis
Hysterectomy is done for what ?
Endometriosis
cancer
Ductal carcinoma

Lobular carcinoma

Medullary carcinoma

Mucinous carcinoma

Tubular ductal carcinoma

Inflammatory breast cancer

what type of cancers are these?
breast cancers
what does the breast cancer feel like to the patient?
Painless mass

Firm, irregular shaped

Fixed to underlying structures
Painless mass

Firm, irregular shaped

Fixed to underlying structures are s/s of what type of cancer?
breast cancer
what lp type of tests should the patient do for breast cancer to help detecct early breast cancer?
Physical exam every three years until 40, then yearly

Base-line mammogram at age 40

Monthly self exams

After each period

Post menopause, same day each month
After Surgery what should the nurse keep in mind for the breast cancer patient?
No needle sticks to affected side

No blood pressures to affected side

Elevation of affected arm

No lifting with affected arm
Metastasizes widely to the abdomen through the peritoneal fluid.

Incidence is low, mortality is high
Ovarian Cancer
Most common in men older than 50

Third most common cause of cancer deaths in men

Grows slowly

High survival rate if detected early

Cause unknown but R/T diets high in fat
Prostate Cancer
s/s:
Decreased urinary flow and difficulty starting stream

Back pain

Hematuria

Hemospermia

Erectile dysfunction
Prostate Cancer
what are the 3 types of :
Most common type of cancer in the US
Increased exposure to UV radiation increases risk
Basal Cell Carcinoma

Squamous Cell Carcinoma

Malignant Melanoma
Nursing Management of the Client With Cancer what should the nurrse do for her pateint?
Pain control and comfort

Can be from obstruction, or nerve compression by a tumor
what are the s/s for an infection the nurse needs to look for?
Fever

Elevated WBC count

Pain redness

Drainage

Bleeding

Immobility

Alterations in body image

Changes in psychological and mental status

Grieving

Emotional support to client and family

Side effects of chemotherapy and radiation
what are the client and family teching the nurse can do?
Medications, treatment and procedures

Adverse effects associated with treatment

Resources for support

Follow-up needed after discharge from the hospital

Must allow time for clients to express their feelings or discuss home care