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40 Cards in this Set
- Front
- Back
Define Hematopoiesis |
Hematopoiesis is the complex process of the formation and maturation of blood cless |
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Type of anemia resulting from red blood cell destruction |
Hemolytic anemia |
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Define Anemia |
Lower than normal hemoglobin and fewer than normal circulation erythrocytes. A sign of an underlying disorder |
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What is Hypoproliferative anemia |
Defect in production of RBC's |
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Hypoproliferative Anemia Patho |
Due to iron, V B12 or folate deficiency. Decreased erythropoietin production, cancer. |
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What is Hemolytic anemia |
Excess destruction of RBC's |
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Hemolytic anemia patho |
Due to altered erythropoiesis, or other causes such as hypersplenism, drug-induced or auto-immune processes, mechanical heart valve. |
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S/S of anemia |
Fatigue, weakness, malaise, pallor, jaundice, cardiac or respiratory problems, tongue changes, nail changes, angular cheilosis, and pica. |
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Medical Management of anemia |
Correct/control underlying cause. Transfusion. Treatment to specific type: dietary, vitamin supplement, etc. |
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Potential anemia problems |
heart failure, angina, paresthesias, and confusion. |
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Anemia nursing interventions |
Balance activity, exercise, and rest. Maintain adequate nutrition, pt education, monitor VS, monitor for potential complications. |
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Define Leukemia |
Hematopoietic malignancy with unrelated proliferation of leukocytes |
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What increase absorption of iron |
Vitamin C |
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Acute Myeloid Leukemia (AML) |
Defect in stem cell that differentiate into all myeloid cells: monocytes, granulocytes, erythrocytes, and platelets. Most common nonlymphocytic leukemia. Peak incident at age 60. |
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S/S of Acute Myeloid Leukemia (AML) |
fever and infection, weakness and fatigue, bleeding tendencies, pain from enlarges liver or spleen, hyperplasia of gums, bone pain |
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When there is low hemoglobin the heart ______ |
Pumps faster |
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Medical management of Acute Myeloid Leukemia (AML) |
Chemotherapy-induction therapy, BMT or PBSCT |
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Chronic Myeloid Leukemia (CML) |
Mutation in myeloid stem cell with uncontrolled proliferation of cells-Philadelphia chromosome. Uncommon in people under 20. Mean age 55-60. Life expectancy 3-5 years. |
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Three stages of Chronic Myeloid Leukemia (CML) |
Chronic phase, transformational phase, blast crisis |
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Signs and symptoms of Chronic Myeloid Leukemia (CML) |
Initially may be asymptomatic, malaise, anorexia, weight loss, confusion or SOB due to leukostasis, enlarged tender spleen, or enlarged liver. |
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Medical management of Chronic Myeloid Leukemia (CML) |
imatinib mestylate (Gleevec) blocks signals in leukemic cells that express BCR-ABL protein; chemotherapy, BMT or PBSCT |
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Acute Lymphocytic Leukemia |
Uncontrolled proliferation of immature cells from lymphoid stem cell. Most common in young children, boys more often than girls. 8-% 5-year event-free survival, but drops with increased age. |
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S/S of Acute Lymphocytic Leukemia |
Leukemic cell infiltration is more common with this leukemia, with symptoms of meningeal involvement and liver, spleen, and bone marrow pain |
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Medical management of Acute Lymphocytic Leukemia |
Chemotherapy, imatinib mestylate (if Philadelphia chromosome positive), BMT or PBSCT, monoclonal antibody therapy. |
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Chronic Lymphocytic Leukemia |
Malignant B lymphocytes, most of which are mature, may escape apoptosis, resulting in excessive accumulation of cells. Most common form of Leukemia. Most common in older adults, effects men more often. Survival 2-14 years depending upon stage |
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S/S of Chronic Lymphocytic Leukemia |
Lymphadenopathy, hepatomegaly, splenomegaly; in later stages anemias and thromocytopenia; autoimmune complications with RES destroying RBC's and platelets may occur, B symptoms include fever, sweats, weight loss. |
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Medical management of Chronic Lymphocytic Leukemia |
early stage may require no treatment, chemotherapy, monoclonal antibody therapy |
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Potential Leukemia Problems |
Infection, bleeding, renal dysfunction, tumor lysis syndrome, nutritional depletion, mucositis, depression |
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Leukemia nursing interventions |
reduce risk for infection and bleeding. Frequent, gentle oral hygiene. |
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Improving Nutrition for Leukemia |
Oral care before and after meals, analgesics before meals, appropriate treatment of nausea, small, frequent feedings, soft foods, low-microbial diet, nutritional supplements. |
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Disseminated intravascular coagulation (DIC) |
A condition in which blood clots from throughout the body's small blood vessels. These blood clots can reduce or block flow through the blood vessels, which can damage the body's organs. Severity is variable; may be life-threatening. |
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Disseminated intravascular coagulation (DIC) triggers |
Sepsis, trauma, shock, cancer, abrupto placentae, toxins, and allergic reactions |
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Medical management of Disseminated intravascular coagulation (DIC) |
treat underlying cause, correct tissue ischemia, replace fluids and electrolytes, maintain blood pressure, replace coagulation factors, use heparin. |
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Potential Disseminated intravascular coagulation (DIC) complications |
Renal failure, Gangrene, pulmonary embolism, hemorrhage, acute respiratory distress symdrome, stroke |
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Disseminated intravascular coagulation (DIC) Nursing interventions |
Assessment and interventions should target potential site of organ damage. Monitor and assess carefully. Avoid trauma and prodecures which increase risk of bleeding, including activities which would increase intracranial pressure. |
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Hematologic System Structures |
blood, bone marrow, spleen, lymph system) |
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Bone marrow aspiration and Biopsy |
Out pt procedure, lies on back or side, gets local anesthetic agents, feels pressure, a few seconds of sharp pain during aspiration, <1 hr procedure |
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Post-bone marrow aspiration care |
pressure dressing on site, monitor VS, monitor for bleeding, lie on aspirated side for 30-60 mins |
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Iron Deficiency Anemia |
without transferrin (carries iron) iron cannot be out in circulatory system. Ferritin (stores iron in liver & heart) iron should not be excreted (in urine or stool). |
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Iron Deficiency Anemia risk factors |
Inadequate dietary intake, malabsorption, GI surgery, loss of blood, premenopausal women, hemorrhage, chronic renal failure |