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56 Cards in this Set

  • Front
  • Back
Epinephrine
1.      a1, a2, b1, b2
Norepinephrine
2.     a1, a2, b1 (no b2 activity)
GABA
3.     Causes an inhibitory cell hyperpolarization
Muscarinic-r
4.     Uses DAG & IP3 as 2nd messengers
Muscarinic-r
5.     Parasympathetic control
Bethanechol
6.     Cholinergic. ­ GI & Bladder motility. Txt atonic bladder post-op
Pilocarpine
7.     Cholinergic. Pupillary constriciton= miosis. Ciliary constriction= accomodation.
Pilocarpine
8.     Txt acute glaucoma
Isoflurophate
9.     Organophosphate. Irreversible acetylcholinesterase (-)r
Pralidoxime
10.   “2PAM”. Reverses organophosphate binding to acetylcholinesterase
Neostigmine
11.    Reversible acetylcholinesterase (-)r
Neostigmine
12.  Txt Myasthenia Gravis
Myasthenia Gravis
13.   Anitbodies to Ach-r. ­’g muscular weakness due to Ach’s weak postsynaptic effect @ NMJ. Inactivates-r
Tubocurium
14.   Nondepol. Competitive cholinergic N-r (-)r.
Tubocurium
15.   Prevents Ach binding but does not activate NMJ
Tubocurium
16.   ­ Histamine release= ¯ BP & ­ bronchospasm
Trimethaphan
17.   Nonselectively binds N-r of the PS- and SNS
Pancurium
18.   More potent than tubocurium w/o histamine release
Succinylcholine
19.   Depol. Non competitive (-)r of muscle aciton
Succinylcholine
20.   Opens Na Ch.= fasciculations. Closes Na Ch.= paralysis. Continuous infusion.
a1 & Eye
21.   Mydriasis due to norepinephrine. Prazosin (-).
M-r & Eye
22.   Miosis due to Ach. Atropine (-).
Sympathetic
23.   Post ganglionic symapthetic fibers releases norepinephrine
Parasym.
24.   Post ganglionic parasympathetic fibers release Ach
M3-r & Eye
25.   Contracts sphincter = miosis. Contracts ciliary = accomodation.
M2-r & Heart
26.   Negative chronotropy: ¯ HR = vagal arrest
M2-r & Heart
27.   Negative inotropy: ¯ contractility
M3-r & Lung
28.   Bronchospasm ­secretions
M3-r & GI
29.   ­ motility (cramps & diarrhea). Involuntary defecation
Tacrine
30.   Acetylcholine esterase (-)r. Txt Alzheimer’s
Atropine
31.  DOC w/ vagal arrest
Glycoperrolate
32.   M-r(-). Antispasmodic. Txt peptic ulcers.
Pirenzepine
33.   M-r(-). Antispasmodic. Txt peptic ulcers.
Doxacurium
34.   Most potent competitive non-depol NMJ (-)r. No cardiovascular side effects. No Histamine release.
b bungarotoxin
35.   Prevent the releasal of Ach from vesicles @ the pre synaptic nerve ending
a bungarotoxin
36.   Irreversible N-r (-)r = ¯ action potentials
a1 & Eye
37.   Contracts radial muscle = mydriasis (pupil dilation)
a1 & Arterioles
38.   Constiction: ­TPR = ­ Diastolic pressure = ­ Afterload
a1 & Venules
39.   Constriction: ­ Venous return = ­ Preload
a1 & Sex Function
40.   Ejaculation
­ Diastolic
41.   ­ a1 = ­TPR
¯ Diastolic
42.   ­ b2; Direct acting vasodilators; (+)Cholinergics
b1 & Heart
43.   (+)chronotropism = ­HR.
b1 & Heart
44.   (+)inotropism = ­ contractility; ­SV; ­CO; ­O2 consumption.
b1 & Heart
45.   ­ conduction velocity
Phenylephrine
46.   a1 (+) Nasal decongestant.
b2(+) Asma Drugs
47.   Metaproterenol; Albuterol; Terbutaline; Ritodrine; Salmeterol
Ritodrine/Turbutaline
48.   Relaxes myometrium used in pre-mature labor pains
Phentolamine
49.   Epi reversal. Blocks a, vasodilation occurs. Pt goes from HyperTN to HypoTN.
Phentolamine
50.  Txt pheochromocytoma = ¯BP
Terazosin
51.  Txt BPH
Yohimbine
52.   ­ sympathetic outflow = a2 (-). Txt impotence.
Cardioselective NMJ
53.   Pancuronium = ­HR due to atropine-like anti muscarinic vagolytic effect & Gallamine (-)r
Ecothiophate
54.   Irreversible cholinesterase (-)r.
Pyridostigmine
55.   Cholinomimetic that ­s M & N-r effects. (-) acetylcholinesterase & plasma cholinesterase
Pyridostigmine
56.  DOC for the oral Txt of MG